Washington State University (1983), Chemistry
Graduate School
Uni of Wisconsin-Madison (1990), Chemistry

Research Interest

  • Molecular mechanisms of neurotransmitter release, as studied by x-ray crystallography.
  • Structure and function of lipoproteins from the bacterium T. pallidum, the causative agent of syphilis.
  • Structure and mechanism of enzymes and metalloenzymes.
  • Structure of proteins involved in cell signaling and division.


Featured Publications LegendFeatured Publications

SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Bae SJ, Ni L, Osinski A, Tomchick DR, Brautigam CA, Luo X Elife 2017 Oct 6
Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Voleti R, Tomchick DR, S├╝dhof TC, Rizo J Proc. Natl. Acad. Sci. U.S.A. 2017 Sep
Functional clues from the crystal structure of an orphan periplasmic ligand-binding protein from Treponema pallidum.
Brautigam CA, Deka RK, Liu WZ, Tomchick DR, Norgard MV Protein Sci. 2017 Feb

Honors & Awards

  • American Heart Association Postdoctoral Fellowship
  • National Merit Scholar
    Washington State University (1979-1983)

Professional Associations/Affiliations

  • American Association for the Advancement of Science (1989-2018)
  • American Chemical Society (1986-2018)
  • American Crystallographic Association (1986-2018)
  • American Society for Microbiology (2003-2018)