Dominika Borek, Ph.D. Titles and Appointments Professor Schools Medical School | Graduate School Departments Biophysics | Biochemistry Graduate Programs Biomedical Engineering, Molecular Biophysics Biography Dr. Dominika Borek received her M.Sc. in Chemistry and Ph.D. in Physical Chemistry from Adam Mickiewicz University in Poland and completed postdoctoral training at UT Southwestern. Her work integrates X-ray crystallography, cryo-EM, electron tomography, and computational analysis to study challenging macromolecular systems and advance structural biology methods. Education Graduate School Adam Mickiewicz University-Pol (1997), Chemistry Graduate School Adam Mickiewicz University-Pol (2001), Physical Chemistry Graduate School Univ of London-Uni College (2001), Structural Biology Research Interest chromatin structure evolution next generation sequencing structural biology Publications Featured Publications Analysis of the heterogenous structural states of the hexameric ATPase PilU of the type IV pili from Vibrio cholerae. Guo Y, Shukla S, Minasov G, Inniss NL, Klose T, Tokars VL, Mondragón A, Otwinowski Z, Borek D, Satchell KJF, Protein Sci 2026 Jun 35 6 e70609 The distinct trimeric structure of the immunodominant chlamydial antigen Major Outer Membrane Protein. Guo Y, Shelby ML, D'haeseleer P, Pal S, Slepenkin A, Robinson BV, Otwinowski Z, Segelke BW, Coleman MA, Borek D, de la Maza LM, Nat Commun 2026 Jun 17 1 Cryo-electron tomography reveals OmpB is required for the Rickettsia parkeri S-layer. Bacher MC, Serwas D, Han Y, Borek D, Welch MD, MicroPubl Biol 2026 2026 Validation of 3D cryoEM single-particle reconstruction correctness and handedness with Ewald's sphere correction. Bromberg R, Guo Y, Borek D, Otwinowski Z, Struct Dyn 2025 Sep 12 5 054301 Solvent organization in the ultrahigh-resolution crystal structure of crambin at room temperature. Chen JCH, Gilski M, Chang C, Borek D, Rosenbaum G, Lavens A, Otwinowski Z, Kubicki M, Dauter Z, Jaskolski M, Joachimiak A, IUCrJ 2024 Sep 11 Pt 5 649-663 CryoEM single particle reconstruction with a complex-valued particle stack. Bromberg R, Guo Y, Borek D, Otwinowski Z, J Struct Biol 2023 Jun 215 2 107945 Monomer and dimer structures of cytochrome bo3 ubiquinol oxidase from Escherichia coli. Guo Y, Karimullina E, Emde T, Otwinowski Z, Borek D, Savchenko A, Protein Sci 2023 Apr 32 4 e4616 High-resolution cryo-EM reconstructions in the presence of substantial aberrations. Bromberg R, Guo Y, Borek D, Otwinowski Z, IUCrJ 2020 May 7 Pt 3 445-452 Real-space analysis of radiation-induced specific changes with independent component analysis. Borek D, Bromberg R, Hattne J, Otwinowski Z J Synchrotron Radiat 2018 Mar 25 Pt 2 451-467 Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses. Chatterjee S, Luthra P, Esaulova E, Agapov E, Yen BC, Borek DM, Edwards MR, Mittal A, Jordan DS, Ramanan P, Moore ML, Pappu RV, Holtzman MJ, Artyomov MN, Basler CF, Amarasinghe GK, Leung DW Nat Microbiol 2017 Jun 2 17101 Results 1-10 of 75 1 2 3 4 5 Next Last Honors & Awards NARSAD Young Investigator Award (2005) Professional Associations/Affiliations American Crystallographic Association
