
Wen-Hong Li, Ph.D.
Associate Professor
Endowed Title Southwestern Medical Foundation Scholar in Medical Research
Department Cell Biology | Biochemistry | Biomedical Engineering
Graduate Programs Biological Chemistry, Biomedical Engineering
Education
- Undergraduate
- Univ of Sci and Tech of China
- Undergraduate
- University of Science Technolo
- Graduate School
- University of California-San D (1993)
- Graduate School
- University of California-San D (1996)
Research Interest
- Cell biology of diabetes and insulin release in islet beta cells
- Functional analysis of microRNAs
- Probe engineering and chemical biology
Publications
Featured Publications
- Temporal and Spatial Regulation of MicroRNA Activity with Photoactivatable Cantimirs.
- Zheng G, Cochella L, Liu J, Hobert O, Li WH ACS Chem. Biol. 2011 Dec 6 12 1332-8
- Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR).
- Li D, Chen S, Bellomo EA, Tarasov AI, Kaut C, Rutter GA, Li WH Proceedings of the National Academy of Sciences of the United States of America 2011 Dec
- Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent.
- Zheng G, Ambros V, Li WH Silence 2010 1 1 9
- Imaging dynamic cell-cell junctional coupling in vivo using Trojan-LAMP
- Yan-Ming Guo, Shiuhwei Chen, Premnath Shetty, Genhua Zheng, Rueyling Lin, Wen-hong Li Nature Methods 2008 5 835-841
- LAMP, A New Imaging Assay of Gap Junctional Communication Unveils That Ca2+ Influx Inhibits Cell Coupling
- Kenneth Dakin, YuRui Zhao & Wen-hong Li Nature Methods 2005 2 55-62 (News & Views, 12-14)
- Photoactivatable and Water Soluble FRET Dyes with High Uncaging Cross Section
- Genghua Zheng, Yan-Ming Guo & Wen-hong Li J. Am. Chem. Soc. 2007 129 10616-10617
- Cell Membrane Permeable Esters of D-myo-Inositol 1,4,5-Trisphosphate
- Kenneth Dakin & Wen-hong Li Cell Calcium 2007 42 291-301
- Infrared LAMP, Two-Photon Uncaging and Imaging of Gap Junctional Communication in Three Dimensions
- Kenneth Dakin & Wen-hong Li Nature Methods 2006 3 959
- Local Ca2+ Rise Near Store Operated Ca2+ Channels Inhibits Cell Coupling During Capacitative Ca2+ Influx
- Kenneth Dakin & Wen-hong Li Cell Commun. Adhes. 2006 13 29-39
- A New Class of Macrocyclic Lanthanide Complexes for Cell Labeling and Magnetic Resonance Imaging Applications
- Quan Zheng, Houquan Dai, Matthew E. Merritt, Craig Malloy, CaiYuan Pan & Wen-hong Li J . Am. Chem. Soc. 2005 127 16178-16188
Honors & Awards
- Junior Investigator Award
American Cancer Society (2002) - Career Development Award
American Diabetes Association (2001) - Martin D. Karmen Prize
In recognition of the excellence of Ph.D. thesis, UCSD (1997) - Jane Hart Memorial Award
Department of Chemistry and Biochemistry, University of California, San Diego (1994)
Professional Associations/Affiliations
- The American Chemical Society
- The American Diabetes Association (2006)
- The American Society for Cell Biology