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John Giacona, Ph.D.

John Giacona, Ph.D.

Titles and Appointments

Assistant Professor

Schools
School of Health Professions
Departments
Applied Clinical Research | Internal Medicine
  • Biography

    John Giacona, Ph.D., PA-C, is an Assistant Professor in the Applied Clinical Research Department at UT Southwestern Medical Center. He holds a secondary appointment in the Department of Internal Medicine. He is a board-certified Physician Assistant and certified Hypertension Specialist practicing at the Clinical Heart and Vascular Center as a member of the Hypertension Section in the Division of Cardiology.

    Dr. Giacona earned his Bachelor of Science and Arts in Biology from The University of Texas at Austin. He received his Master of Physician Assistant Studies and Doctor of Philosophy degrees from UT Southwestern Medical Center.

    His research focuses on the role of nutrition and exercise in the autonomic regulation of blood pressure, high-density lipoprotein metabolism, and skeletal muscle mitochondrial function, with a growing emphasis on cardiometabolic contributions to brain health and cognitive decline. He is funded by the North Texas Alzheimer’s Disease Research Center (ADRC) at UT Southwestern to investigate mechanisms linking hypertension and metabolic dysfunction to cerebrovascular outcomes.

    In addition to his research, Dr. Giacona contributes to medical education through the Departments of Physician Assistant Studies and Healthcare Sciences, where he leads the cardiovascular and endocrinology clinical medicine sections of the curriculum.

    Dr. Giacona currently serves as a board member of the Academy of Physician Associates in Cardiology as President-Elect and Chair of Preventive Cardiology, and is a member of several other professional organizations, including the American Academy of Physician Assistants, the American College of Cardiology, and the Texas Academy of Physician Assistants. He also serves as a member on the American Heart Association's Hypertension Professional/Public Education & Publications Committee for the Council on Hypertension.

  • Education
    Graduate School
    UT Southwestern Medical Center (2021), Physician Assistant
  • Research Interest
    • Clinical Lipidology
    • Mitochondrial Function
    • Neural Control of Blood Pressure
    • Primary Aldosteronism
    • Resistant Hypertension
    • Skeletal Muscle Energetics
  • Publications

    Star Featured Publications

    Featured Featured Featured Featured Featured Featured Featured Featured Featured
    Trends in Salt Substitute Use Among Adults in the United States from 2003 to 2020.
    Wei Y, Abraham J, Sandon L, Wang J, Price A, Giacona JM, Vongpatanasin W, Hypertension 2026 Mar 83 3 e26196
  • Books

    Featured 

  • Honors & Awards
    • ADRC Research Scholar
      North Texas Alzheimer's Disease Research Center (2026)
    • Stroke Council Award and Travel Grant
      American Heart Association (2024)
    • Outstanding Graduate Student Award in Honor of Jon Williamson, PhD
      UT Southwestern Applied Clinical Research Department (2023)
    • Student Excellency in Service Award in Honor of John Schermerhorn, MD
      UT Southwestern School of Health Professions (2023)
    • Capra Symposium Research Competition Winner
      UT Southwestern School of Health Professions (2022)
    • Student Excellency in Research Award in Honor of Raul Caetano, MD, PhD
      UT Southwestern School of Health Professions (2022)
    • Alpha Eta National Honor Society
      UT Southwestern School of Health Professions (2020)
    • Pi Alpha National Physician Assistant Honor Society
      UT Southwestern School of Health Professions (2020)
    • Student Excellency in Clinical Care Award in Honor of Gordon Green, MD
      UT Southwestern School of Health Professions (2020)
    • Student Excellency in Leadership Award in Honor of Ruth Guy, MD
      UT Southwestern School of Health Professions (2020)
  • Professional Associations/Affiliations
    • Academy of Physician Associates in Cardiology (2022)
    • American Academy of Physician Associates (2017)
    • American College of Cardiology (2021)
    • American Heart Association (2021)
    • American Physiological Society (2022)
    • Primary Aldosteronism Foundation (2024)