Dr. Yazdani received his Bachelor of Science from Punjab University in Lahore, Pakistan in 1994 and his medical degree from King Edward Medical University in Lahore, Pakistan in 1997. After a postdoctoral fellowship at the University of Texas Southwestern Medical Center Dallas from 1999-2005. Dr. Yazdani held a faculty appointment in the Department of Neuroscience at UT Southwestern from 2005-10.
His scientific interests included understanding the mechanisms responsible for neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease using human brain tissue and serum samples along with using animal models. His work also involved seeking blood biomarkers for Parkinson’s disease and Autism spectrum disorder. Blood samples from patients with these diseases were analyzed to identify potential antibody and protein biomarkers that could be used to diagnose the diseases, and possibly identify these diseases before onset of symptoms. He has authored multiple peer reviewed journal publications over the years.
Dr. Yazdani joined the faculty of the Department of Neurology and Neurotherapeutics for Movement Disorders at UT Southwestern in December 2019.
- University of the Punjab (1994), Science
- Medical School
- King Edward Medical University (1997), Medicine
- Blood biomarkers for neurodegenerative diseases.
- Mechanisms of neurodegenerative diseases.
- Neuromodulation network, quality improvement study in Deep Brain Stimulation for Movement Disorders.
- Comparison of Globus Pallidus Interna and Subthalamic Nucleus in Deep Brain Stimulation for Parkinson Disease: An Institutional Experience and Review.
- Mirza S, Yazdani U, Dewey Iii R, Patel N, Dewey RB, Miocinovic S, Chitnis S, Parkinsons Dis 2017 2017 3410820
- Blood biomarker for Parkinson disease: peptoids.
- Yazdani U, Zaman S, Hynan LS, Brown LS, Dewey RB, Karp D, German DC, NPJ Parkinsons Dis 2016 2
- Rat model of Parkinson's disease: chronic central delivery of 1-methyl-4-phenylpyridinium (MPP+).
- Yazdani U, German DC, Liang CL, Manzino L, Sonsalla PK, Zeevalk GD, Exp. Neurol. 2006 Jul 200 1 172-83
- Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions.
- Chandra S, Fornai F, Kwon HB, Yazdani U, Atasoy D, Liu X, Hammer RE, Battaglia G, German DC, Castillo PE, Südhof TC, Proc. Natl. Acad. Sci. U.S.A. 2004 Oct 101 41 14966-71
- Serum thyroid-stimulating hormone and interleukin-8 levels in boys with autism spectrum disorder.
- Singh S, Yazdani U, Gadad B, Zaman S, Hynan LS, Roatch N, Schutte C, Marti CN, Hewitson L, German DC, J Neuroinflammation 2017 06 14 1 113
- A Search for Blood Biomarkers for Autism: Peptoids.
- Zaman S, Yazdani U, Deng Y, Li W, Gadad BS, Hynan L, Karp D, Roatch N, Schutte C, Nathan Marti C, Hewitson L, German DC, Sci Rep 2016 Jan 6 19164
- Administration of thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology.
- Gadad BS, Li W, Yazdani U, Grady S, Johnson T, Hammond J, Gunn H, Curtis B, English C, Yutuc V, Ferrier C, Sackett GP, Marti CN, Young K, Hewitson L, German DC, Proc. Natl. Acad. Sci. U.S.A. 2015 Oct 112 40 12498-503
- Inducible neuronal inactivation of Sim1 in adult mice causes hyperphagic obesity.
- Tolson KP, Gemelli T, Meyer D, Yazdani U, Kozlitina J, Zinn AR, Endocrinology 2014 Jul 155 7 2436-44
- Mical links semaphorins to F-actin disassembly.
- Hung RJ, Yazdani U, Yoon J, Wu H, Yang T, Gupta N, Huang Z, van Berkel WJ, Terman JR, Nature 2010 Feb 463 7282 823-7
- The glucose transporter (GLUT4) enhancer factor is required for normal wing positioning in Drosophila.
- Yazdani U, Huang Z, Terman JR, Genetics 2008 Feb 178 2 919-29
Candidate selection for Deep Brain Stimulation in Essential tremor. In Deep Brain Stimulation: a Case-based Approach.
Shilpa Chitnis, Pravin Khemani, and Michael S. Okun (2020). Oxford University Press
Honors & Awards
- Postdoctoral Research Fellowship Award
UT Southwestern (2004)
- American Academy of Neurology (2015)
- Movement Disorder Society (2015)