Biography

Dr. Rakheja did his medical schooling at All India Institute of Medical Sciences in New Delhi.  He completed pathology residencies at Maulana Azad Medical College (Delhi University) and UT Southwestern Medical Center. He trained in gastrointestinal pathology and neuropathology as a senior resident (fellow equivalent) at GB Pant Hospital (Delhi University) and completed a pediatric pathology fellowship at UT Southwestern/Children’s Medical Center.

Dr. Rakheja studies the genetics and metabolism of childhood cancer, particularly Wilms tumor, germ cell tumors, hepatoblastoma, brain tumors, and pediatric sarcomas of bone and soft tissue. He has specific interests in tumor tissue banking, establishing primary pediatric cancer cell lines, and developing laboratory assays for diagnostic, prognostic, and therapeutic targets in pediatric cancers. 

Education

Medical School
All India Institute of Medical Sciences, India (1993)
Residency
Maulana Azad Hospitals (1997), Pathology
Residency
G. B. Pant Hospital (1999), Pathology
Residency
UT Southwestern Medical Center (2003), Pathology
Fellowship
UT Southwestern/Children's Medical Center (2006), Pediatric Pathology

Research Interest

  • Cancer metabolism
  • Neuroblastoma
  • Pediatric brain cancers
  • Pediatric gentourinary cancers
  • Pediatric liver cancers
  • Pediatric sarcomas

Publications

Featured Publications LegendFeatured Publications

Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
Shelar S, Shim EH, Brinkley G, Kundu A, Carobbio F, Poston T, Tan J, Parekh V, Benson D, Crossman DK, Buckhaults PJ, Rakheja D, Kirkman R, Sato Y, Ogawa S, Dutta S, Velu SE, Emberley E, Pan A, Chen J, Huang T, Absher D, Becker A, Kunick C, Sudarshan S Clin. Cancer Res. 2018 Aug
Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes.
Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX Cell Rep 2018 Jul 24 1 238-251
ACTG2-Associated Visceral Myopathy With Chronic Intestinal Pseudoobstruction, Intestinal Malrotation, Hypertrophic Pyloric Stenosis, Choledochal Cyst, and a Novel Missense Mutation.
Collins RRJ, Barth B, Megison S, Pfeifer CM, Rice LM, Harris S, Timmons CF, Rakheja D Int. J. Surg. Pathol. 2018 Jul 1066896918786586
Myelodysplastic Syndrome and Sweet's Syndrome Are Associated with a Mutation in Isocitrate Dehydrogenase 1.
Snyder R, Libby T, Raciti P, Amin B, Jacobson M, Rakheja D, Fleming K, Bartenstein M, Zhu C, Goel S, Verma AK, Shastri A Anticancer Res. 2018 04 38 4 2201-2205
EGF Receptor and mTORC1 are novel therapeutic targets in nonseminomatous germ cell tumors.
Chen KS, Fustino NJ, Shukla AA, Stroup EK, Budhipramono A, Ateek C, Stuart SH, Yamaguchi K, Kapur P, Frazier AL, Lum L, Looijenga LHJ, Laetsch TW, Rakheja D, Amatruda JF Mol. Cancer Ther. 2018 Feb

Books

Featured Books Legend Featured Books

Cholesterol biosynthetic disorders: a review. In Focus on Cholesterol Research

Rakheja D, Rogers BB, Bennett MJ (2006). Hauppauge, NY, Nova Publications

The "fussy" neonate. In Tietz's Applied Laboratory Medicine

Jones PM, Rakheja D (2007). Hoboken, NJ, Wiley-Interscience, John Wiley & Sons Inc.

Quick Guide to Organic Acid Interpretation

Jones PM, Rakheja D (Ed.) (2011). Washington, DC, American Association for Clinical Chemistry Press

The "sleepy" neonate. In Tietz's Applied Laboratory Medicine

Rakheja D, Jones PM (2007). Hoboken, NJ, Wiley-Interscience, John Wiley & Sons Inc.

Glomerular diseases associated with nephritic syndrome and/or rapidly progressive glomerulonephritis. In Silva's Diagnostic Renal Pathology

Rogers T, Rakheja D, Zhou XJ (2009). New York, NY, Cambridge University Press

The aging kidney. In Silva's Diagnostic Renal Pathology

Zhou XJ, Rakheja D, Silva FG (2009). New York, NY, Cambridge University Press

Pathology of germ cell tumors. In Pediatric Germ Cell Tumors

Rakheja D, Teot L (2014). New York, NY, Springer

Honors & Awards

  • John Lawrence and Patsy Louise Goforth Distinguished Professorship in Pathology
    (2013)
  • Pediatric Pathology Visiting Scholar, Children’s Hospital Boston, Harvard Medical School
    (2006)
  • College of American Pathologists Foundation (CAPF) Scholar
    (2004)
  • Harry B. Neustein Memorial Award, Society for Pediatric Pathology
    (2004)
  • Travel Award for junior investigators, Society for Inherited Metabolic Disorders
    (2004)
  • F. Stephen Vogel Award, United States and Canadian Academy of Pathology
    (2003)
  • Dr. R. P. Mathur Memorial Award in Pathology, Maulana Azad Medical College (Delhi University)
    (1997)