Research Interest

  • Multidrug resistance, Gram-negative infections, Pharmacokinetics, Pharmacodynamics, Beta-lactamase inhibitors

Publications

Featured Publications LegendFeatured Publications

Humanized Exposures of a ß-Lactam-ß-Lactamase Inhibitor, Tazobactam, versus Non-ß-Lactam-ß-Lactamase Inhibitor, Avibactam, with or without Colistin, against Acinetobacter baumannii in Murine Thigh and Lung Infection Models.
Monogue ML, Sakoulas G, Nizet V, Nicolau DP Pharmacology 2018 101 5-6 255-261
Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa.
Ghazi IM, Monogue ML, Tsuji M, Nicolau DP Pharmacology 2018 101 5-6 278-284
Microdialysis.
Stainton SM, Monogue ML, Baummer-Carr A, Shepard AK, Nugent JF, Kuti JL, Nicolau DP Antimicrob. Agents Chemother. 2018 01 62 1
Pharmacokinetics and Tissue Penetration of Ceftolozane-Tazobactam in Diabetic Patients with Lower Limb Infections and Healthy Adult Volunteers.
Monogue ML, Stainton SM, Baummer-Carr A, Shepard AK, Nugent JF, Kuti JL, Nicolau DP Antimicrob. Agents Chemother. 2017 12 61 12
Translational Efficacy of Humanized Exposures of Cefepime, Ertapenem, and Levofloxacin against Extended-Spectrum-ß-Lactamase-Producing Escherichia coli in a Murine Model of Complicated Urinary Tract Infection.
Monogue ML, Nicolau DP Antimicrob. Agents Chemother. 2017 11 61 11
Efficacy of Humanized Exposures of Cefiderocol (S-649266) against a Diverse Population of Gram-Negative Bacteria in a Murine Thigh Infection Model.
Monogue ML, Tsuji M, Yamano Y, Echols R, Nicolau DP Antimicrob. Agents Chemother. 2017 11 61 11
Discordance with Humanized Piperacillin-Tazobactam Exposures against Piperacillin-Tazobactam-Resistant/Pan-ß-Lactam-Susceptible Klebsiella pneumoniae Strains.
Stainton SM, Monogue ML, Nicolau DP Antimicrob. Agents Chemother. 2017 07 61 7
Activity: Humanized Exposures of Ceftazidime-Avibactam, Aztreonam, and Tigecycline Alone and in Combination against New Delhi Metallo-ß-Lactamase-Producing Klebsiella pneumoniae in a Murine Lung Infection Model.
Monogue ML, Abbo LM, Rosa R, Camargo JF, Martinez O, Bonomo RA, Nicolau DP Antimicrob. Agents Chemother. 2017 07 61 7
Detection of Piperacillin-Tazobactam-Resistant/Pan-ß-Lactam-Susceptible Escherichia coli with Current Automated Susceptibility Test Systems.
Monogue ML, Tanner LK, Brecher SM, Aslanzadeh J, Nicolau DP Infect Control Hosp Epidemiol 2017 03 38 3 379-380
In Vitro-In Vivo Discordance with Humanized Piperacillin-Tazobactam Exposures against Piperacillin-Tazobactam-Resistant/Pan-ß-Lactam-Susceptible Escherichia coli.
Monogue ML, Nicolau DP Antimicrob. Agents Chemother. 2016 12 60 12 7527-7529