Anthony Davis, Ph.D.

Anthony Davis, Ph.D., is an Associate Professor of Radiation Oncology at UT Southwestern Medical Center. He is part of the Department of Radiation Oncology’s Section of Molecular Medicine.

Dr. Davis earned a Bachelor of Science in Biochemistry and a Bachelor of Science in Microbiology from the University of Oklahoma in 1999. He attended graduate school at UT Southwestern Medical Center and received a Ph.D. in cell and molecular biology under the mentorship of Marc Mumby, Ph.D., in the Department of Pharmacology. His graduate research focused on the role of protein phosphatase 2A in regulating the early steps of DNA replication.

Dr. Davis subsequently completed his postdoctoral research under the guidance of David J. Chen, Ph.D., in the Department of Radiation Oncology at UTSW. There, he investigated the cellular response to DNA double-strand breaks (DSBs). In particular, he focused on examining the role that the DNA-dependent protein kinase complex plays in modulating DSB repair pathway choice.

Since 2016, Dr. Davis has led a lab investigating cellular responses to DSBs. Further, his group focuses on understanding aberrant DSB repair and signaling, as well as mechanisms underlying cancer cell resistance to chemotherapy and radiation. Specifically, they explore how cancer cells activate neomorphic pathways to manage DNA replication stress and damage, aiming to identify and target these pathways to combat therapy resistance.