Jeffrey Waugh, M.D., Ph.D. Titles and Appointments Associate Professor School Medical School Department Pediatrics | Neurology Graduate Programs Neuroscience You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Jeffrey Waugh, Ph.D., is an Assistant Professor in the Department of Pediatrics at UT Southwestern Medical Center. He joined the UT Southwestern faculty in 2017. Dr. Waugh earned his medical degree at UT Southwestern Medical School in 2007. Following a year-long internship at UT Southwestern, he completed a residency in pediatrics at UT Southwestern/Children’s Medical Center followed by a residency in pediatric neurology at Harvard Medical School/Boston Children’s Hospital. In 2014, Dr. Waugh completed a fellowship in pediatric movement disorders at Massachusetts General Hospital. Dr. Waugh’s research focuses on pediatric and adult movement disorders, with an emphasis on developing methods for brain imaging in inherited neurological diseases. One recent project involves developing an imaging tool for identifying the striosome and matrix compartments in living human. Education Medical School UT Southwestern Medical School (2007) Residency UT Southwestern/Children's Medical Center (2009), Pediatrics Residency Harvard Medical School/Boston Childrens Hospital (2012), Pediatric Neurology Fellowship Massachusetts General Hospital (2014), Pediatric Movement Disorders Research Interest Functional consequences of dystonia treatment, such as deep brain stimulation Neurophysiology of the neostraitum Structural basis of dystonia The striatal compartments, the striosome and matrix Publications The striatal matrix compartment is expanded in autism spectrum disorder Waugh JL, Hassan AO, Funk AT, Maldjian JA Journal of neurodevelopmental disorders 2025 Dec 17 Chronic Striatal Cholinergic Interneuron Excitation Causes Cerebral Palsy-Related Dystonic Behavior in Mice Gemperli K, Lu X, Chintalapati K, Rust A, Bajpai R, Suh N, Blackburn J, Gelineau-Morel R, Kruer MC, Mingbunjerdsuk D, O'Malley J, Tochen L, Waugh JL, Wu S, Feyma T, Perlmutter J, Mennerick S, McCall JG, Aravamuthan BR Annals of Neurology 2025 Oct 98 726-740 Globally Reduced Brain Volume in Rett Syndrome Dy-Hollins ME, Kapur K, Prohl AK, Sharma N, Yang E, Warfield SK, Waugh JL Pediatric Neurology 2025 Jul 168 60-66 The striatal compartments, striosome and matrix, are embedded in largely distinct resting-state functional networks Sadiq A, Funk AT, Waugh JL Frontiers in Neural Circuits 2025 19 Depression-associated reductions in putaminal volume are accompanied by a shift from matrix-like to striosome-like structural connectivity Tieu AN, Waugh JL Frontiers in Psychiatry 2025 16 Analysis of striatal connectivity corresponding to striosomes and matrix in de novo Parkinson’s disease and isolated REM behavior disorder Marecek S, Krajca T, Krupicka R, Sojka P, Nepozitek J, Varga Z, Mala C, Keller J, Waugh JL, Zogala D, Trnka J, Sonka K, Ruzicka E, Dusek P npj Parkinson's Disease 2024 Dec 10 Emerging Subspecialties: Pediatric Movement Disorders Neurology Kahlon S, Barton CR, Abu Libdeh A, O'Malley JA, Pearson T, Waugh JL, Wu SW, Zea Vera AG, Kruer MC Neurology 2024 Jan 102 In Humans, Insulo-striate Structural Connectivity is Largely Biased Toward Either Striosome-like or Matrix-like Striatal Compartments Funk AT, Hassan AA, Waugh JL Neuroscience Insights 2024 Jan 19 Cachexia, chorea, and pain in chronic nonbacterial osteitis and inflammatory bowel disease: a case report Agharokh L, Mamola K, Yu AG, Medina AL, Gurram B, Fuller J, Park JY, Chen W, Rajaram V, Hammer MR, Waugh JL Journal of Medical Case Reports 2023 Dec 17 Functional Neurological Disorder Among Sexual and Gender Minority People Lerario MP, Rosendale N, Waugh JL, Turban J, Maschi T Neurologic Clinics 2023 Nov 41 759-781 Results 1-10 of 61 1 2 3 4 5 Next Last Books Featured Books Ataxia. In Pediatric Infectious Diseases: Essentials for Practice, 2nd ed, Shah SS, Kemper AR, Ratner AJ, eds. De Gusmao CM, Waugh JL (2018). New York, NY, McGraw-Hill; 114-119 Honors & Awards CTSA-Pilot AwardThe Translational Pilot Program, part of the UTSW NIH-funded CTSA grant, is a funding mechanism for emerging investigators in the biomedical sciences (2022) The Golden Boots AwardSelected by Child Neurology residents as the best educator of the year (2022-2023) Early Stage Investigator AwardAwarded by the NeuroNEXT Network (2021-2022) Chair, Practice Committee, Child Neurology Society (2019) Career Development Award, American Academy of NeurologyThree year award with K-level support (2018-2023) Invited Member, Medical Economics and Management Committee, American Academy of Neurology (2013-2020) Member, Clinical Documentation Integrity Committee, Boston Children's Hospital (2013-2017) Resident Teacher of the Year, Harvard Medical School, Child NeurologyAs voted by Neurology residents (2012) Silverman Family Fellowship, Bachman-Strauss Dystonia Parkinson Foundation (2012-2014) Professional Associations/Affiliations American Academy of Neurology (2009) American Neuropsychiatric Association (2013) Child Neurology Society (2009) Collaborative Center for X-linked Dystonia Parkinsonism, invited member (2014) Functional Neurological Disorders Society (2021) International Child Neurology Association (2016) Movement Disorders Society (2011)
