Lance Terada, M.D. Professor & Division Chief Endowed Title Dr. Carey G. King, Jr. and Dr. Henry M. Winans, Sr. Chair in Internal Medicine School Medical School Department Internal Medicine | Surgery Graduate Programs Cell and Molecular Biology You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Lance Terada, M.D., is a Professor of Internal Medicine at UT Southwestern Medical Center, Chief of its Division of Pulmonary and Critical Care Medicine, and holder of the Dr. Carey G. King, Jr. and Dr. Henry M. Winans, Sr. Chair in Internal Medicine. His clinical interests include general pulmonology and pulmonary disorders. Originally from Honolulu, Dr. Terada received his bachelor’s degree in biophysics from Amherst College in Massachusetts, and his medical degree from the University of Hawaii. His clinical training in internal medicine was at Case Western Reserve University in Cleveland, followed by both clinical and research fellowships in pulmonary sciences at the University of Colorado in Denver, where he also served as a faculty member. He is certified by the American Board of Internal Medicine in internal medicine (1986), pulmonary medicine (1988), and critical care medicine (2010). He joined UT Southwestern in 1999.Dr. Terada’s research focuses on several areas of cellular signaling which control basic mechanical and cell fate decision programs. He is a member of several professional organizations, including the American Federation for Medical Research, American Psychological Society, American Society for Biochemistry and Molecular Biology, and the American Thoracic Society. Dr. Terada’s awards and honors include an Established Investigator Award from the American Heart Association, an Individual Investigator Award from the Cancer Prevention and Research Institute of Texas, membership in the Sigma Xi Scientific Research Honor Society, and the Faculty Teaching Excellence Award from UTSW’s Pulmonary and Critical Care Fellowship. He has been named a Texas Super Doctor by Texas Monthly every year since 2012. Education Medical School University of Hawaii John A. Burns School of Medicine (1983) Residency University Hospitals of Cleveland (1986), Internal Medicine Fellowship University of Colorado Health Sciences Center (1989), Pulmonary Diseases & Critical Care Medicine Research Interest Anchorage sensing and anoikis Oxidant Biochemistry Signal Transduction Vascular Biology Publications Featured Publications Aiolos Promotes Anchorage Independence by Silencing p66(Shc) Transcription in Cancer Cells. Li X, Xu Z, Du W, Zhang Z, Wei Y, Wang H, Zhu Z, Qin L, Wang L, Niu Q, Zhao X, Girard L, Gong Y, Ma Z, Sun B, Yao Z, Minna JD, Terada LS, Liu Z Cancer Cell 2014 May 25 5 575-89 Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation. Wu RF, Ma Z, Liu Z, Terada LS Mol. Cell. Biol. 2010 Jul 30 14 3553-68 Specificity in reactive oxidant signaling: think globally, act locally. Terada LS J. Cell Biol. 2006 Aug 174 5 615-23 Subcellular targeting of oxidants during endothelial cell migration. Wu RF, Xu YC, Ma Z, Nwariaku FE, Sarosi GA, Terada LS J. Cell Biol. 2005 Dec 171 5 893-904 p66Shc restrains Ras hyperactivation and suppresses metastatic behavior. Ma, Z., Z. Liu, R.F. Wu, and L.S. Terada. Oncogene 2010 29 5559-5567 HIV-1 Tat activates dual Nox pathways leading to independent activation of ERK and JNK MAP kinases. Wu RF, Ma Z, Myers DP, Terada LS J. Biol. Chem. 2007 Dec 282 52 37412-9 p66Shc mediates anoikis through RhoA Ma, Z., D.P. Myers, R.F. Wu, F.E. Nwariaku, and L.S. Terada. J. Cell Biol. 2007 179 23 HIV1 Tat activates dual Nox pathways leading to independent activation of ERK and JNK MAP kinases. Wu, R.F., Z. Ma, D.P. Myers, and L.S. Terada. J. Biol. Chem. 2007 282 37412 Endothelial progenitor cell mobilization after percutaneous coronary intervention Banerjee, S., E. Brilakis, S. Zhang, M. Roesle, J. Lindsey, B. Philips, C.G. Blewett, and L.S. Terada Atherosclerosis 2006 189 70-75 p47phox participates in activation of RelA in endothelial cells. Gu, Y., Y.C. Xu, R.F. Wu, F.E. Nwariaku, R.F. Souza, S.C. Flores, and L.S. Terada. J. Biol. Chem. 2003 278 17210-17217 Results 1-10 of 12 1 2 Next Last Honors & Awards American Heart AssociationEstablished Investigator Award (1996) Will Rogers Research Fellow (1988) Research Competition Award - Case Western Research Univ (1986) Alpha Omega Alpha (1982) Professional Associations/Affiliations American Federation for Medical Research American Physiological Society American Society for Biochemistry and Molecular Biology American Thoracic Society
