Dr. Liang received his BS in Biochemistry from Peking University in 1991, and his PhD in Biochemistry from The Ohio state University in 1997. Dr. Liang did postdoctoral research in the laboratory of Drs. Michael Brown and Joseph Goldstein at UT Southwestern and worked as a senior scientist at Eli Lilly. In 2005, Dr. Liang returned to UT Southwestern as an assistant professor in the Department of Molecular Genetics.

Dr. Liang is currently professor in Department of Molecular Genetics and Center for Human Nutrition.



Peking University (1991)
Graduate School
Ohio State University-Main Cam (1997)

Research Interest

  • Cholesterol homeostasis
  • Metabolic diseases such as obesity and diabetes
  • Transcriptional regulation


Featured Publications LegendFeatured Publications

Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver.
Kuriyama H, Liang G, Engelking LJ, Horton JD, Goldstein JL, Brown MS. Cell Metab January 2005 1(1) 41-51
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c.
Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS. J Biol Chem. March 2002 277(11) 9520-8
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta.
Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, Shan B, Brown MS, Goldstein JL, Mangelsdorf DJ. Genes Dev. November 2000 14(22) 2819-30.

Honors & Awards

  • The Hartwell Individual Biomedical Research Award
  • University Fellowship, Ohio State University