Dr. Liang was born in a small farming village of LeiYang (Hunan, P.R. China). He graduated from the second middle school of LeiYang in 1987 and attended Peking University. After graduating with a BS in Biochemistry in July 1991, he came to the US to study at Ohio State University, where he obtained his PhD in Biochemistry in December 1997.

From 1998 to 2002, Dr. Liang did postdoctoral research in the laboratory of Drs. Michael Brown and Joseph Goldstein at UT Southwestern. From July 2002 to September 2004, he worked as a research assistant professor at Molecular Genetics Department at UT Southwestern. From September 2004 to June 2005, he did drug-discovery research as a senior scientist at Eli Lilly.

Since July 2005, he has been an assistant professor in the Department of Molecular Genetics.


Peking University (1991)
Graduate School
Ohio State University-Main Cam (1997)

Research Interest

  • Cholesterol homeostasis
  • Metabolic diseases such as obesity and diabetes
  • Transcriptional regulation


Featured Publications LegendFeatured Publications

Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice.
Guan,H.P., Goldstein, J.L., Brown, M.S., and Liang, G. J. Biol. Chem. September 2009 284 24644-52
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone.
Yang, J., Brown, M.S., Liang, G., Grishin, N.V., Goldstein, J.L. Cell 2008 132 387-396
Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin
Engelking, L.J., Evers, B.M., Richardson, J.A., Goldstein, J.L., Brown, M.S. and Liang, G. J. Clin. Invest. September 2006 116 2356-2365
Schoenheimer effect explained - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS. J Clin Invest September 2005 115 (9) 2489-2498
Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver.
Kuriyama H, Liang G, Engelking LJ, Horton JD, Goldstein JL, Brown MS. Cell Metab January 2005 1(1) 41-51

Honors & Awards

  • The Hartwell Individual Biomedical Research Award
  • University Fellowship, Ohio State University