Biography

Dr. Mammen received his Bachelor in Science and Engineering in Bioengineering at the University of Pennsylvania and his Medical Doctorate at the University of Wisconsin-Madison. He completed an Internal Medicine Residency at the University of Iowa Hospitals & Clinics. In 1998 he arrived at UT Southwestern Medical Center where he completed Fellowships in General Clinical Cardiology, Molecular Cardiology, and Clinical Heart Failure/Cardiac Transplantation. Dr. Mammen’s clinical and scientific focus revolves around heart failure/transplantation.

Education

Medical School
University of Wisconsin School of Medicine (1995)
Internship
University of Iowa Hospitals and Clinics (1996), Internal Medicine
Residency
University of Iowa Hospitals and Clinics (1998), Internal Medicine
Fellowship
UT Southwestern Medical Center (2001), Cardiology
Fellowship
UT Southwestern Medical Center (2004), Molecular Cardiology
Fellowship
UT Southwestern Medical Center (2004), Heart Failure/cardiac Transplant

Research Interest

  • Cardiac energetics
  • Modulation of the metabolic and redox states with stressed cardiomyocytes
  • Oxidative stress
  • Oxygen and nitric oxide metabolism in the heart
  • Regenerative Medicine

Publications

Featured Publications LegendFeatured Publications

Hypoxia-induced left ventricular dysfunction in myoglobin-deficient mice.
Mammen PP, Kanatous SB, Yuhanna IS, Shaul PW, Garry MG, Balaban RS, Garry DJ Am. J. Physiol. Heart Circ. Physiol. 2003 Nov 285 5 H2132-41
Role of the exercise pressor reflex in rats with dilated cardiomyopathy.
Smith SA, Mammen PP, Mitchell JH, Garry MG Circulation 2003 Sep 108 9 1126-32
Neuroprotection and the role of neuroglobin.
Garry DJ, Mammen PP Lancet 2003 Aug 362 9381 342-3
Emerging roles for myoglobin in the heart.
Garry DJ, Kanatous SB, Mammen PP Trends Cardiovasc. Med. 2003 Apr 13 3 111-6
Hypoxia-induced left ventricular dysfunction in myoglobin deficient mice.
Mammen P.P.A., S.B. Kanatous, I. Yuhanna, P. W. Shaul, R.S. Balaban, M.G. Garry, and D.J. Garry Am J Physiol: Heart and Circulatory Physiology 2003 285 H2132-2141
Emerging roles of myoglobin in the heart.
Garry D.J., S.B. Kanatous, and P.P.A. Mammen Trends in Cardiovascular Medicine 2003 13 111-116
Neuroglobin, a novel member of the globin family, is expressed in focal regions of the brain.
Mammen PP, Shelton JM, Goetsch SC, Williams SC, Richardson JA, Garry MG, Garry DJ J. Histochem. Cytochem. 2002 Dec 50 12 1591-8
Adaptive mechanisms that preserve cardiac function in mice without myoglobin.
Meeson AP, Radford N, Shelton JM, Mammen PP, DiMaio JM, Hutcheson K, Kong Y, Elterman J, Williams RS, Garry DJ Circ. Res. 2001 Apr 88 7 713-20
Myocyte-enriched calcineurin interacting protein, MCIP1, inhibits cardiac hypertrophy.
Rothermel B.A., T.A. McKinsey, R.B. Vega, R.L.Nicol, P. Mammen, J. Yang, C. Antos, J.M. Shelton, R. Bassel-Duby, E.N. Olson, and R.S. Williams. Proceedings of the National Academy of Sciences USA 2001 98 3328-3333
Adaptive mechanisms that preserve cardiac function in mice without myoglobin.
Meeson A., N. Radford, J.M. Shelton, P.P.A. Mammen, Y.Kong, J.M. DiMaio, K. Hutcheson, J. Elterman, R.S. Williams, and D.J. Garry Circulation Research 2001 88 713-720

Books

Featured Books Legend Featured Books

Honors & Awards

  • UTSW Leadership Emerging in Academic Departments (LEAD) Program (Class of 2013)
    Only 30 out of 100 UTSW faculty members were chosen to enter the Class of 2013 based on their future leadership potential. (2013-2013)
  • Recipient of a NIH-NHLBI R01 Research Grant
    (2012-2017)
  • Induction as a Fellow into the American Heart Association (Council on Basic Cardiovascular Sciences)
    (2011)
  • Mentor to Diana Canseco PhD, recipient of an AHA Postdoctoral Research Award
    (2011-2013)
  • Diplomate in Advanced Heart Failure/Transplant Cardiology (American Board of Internal Medicine)
    (2010)
  • Postdoctoral Mentor to Sarvjeet Singh, PhD, a Finalist for the Louis N. and Arnold M. Katz Basic Science Research Award
    Highest basic science award given to a junior investigator. The award is sponsored by the American Heart Association (2010)
  • Mentor to Sarvjeet Singh PhD, recipient of an AHA Postdoctoral Research Award
    (2009-2012)
  • Recipient of a AHA Grant-in-Aid Award
    (2009-2012)
  • 2nd Place, Northwestern University Feinberg School of Medicine Cardiovascular Young Investigators’ Forum
    Outstanding research as a junior faculty member (2006)
  • Finalist: Northwestern University Feinberg School of Medicine Cardiovascular Young InvestigatorsÂ’ Forum
    Outstanding research as a cardiology fellow (2005)
  • GlaxoSmithKline Competitive Grant Award for Young Investigators
    One of four cardiovascular investigators in the nation to receive this competitive grant. (2005)
  • Induction as a Fellow into the American College of Cardiology
    (2005)
  • Recipient of a NIH Clinician Scientist Development Award
    (2005-2011)
  • Finalist: AstraZeneca Cardiovascular Young InvestigatorsÂ’ Forum
    (2004)
  • Recipient of the Dr. Madhukar Deshmukh Award (Sponsored by the American Association of Cardiologists of Indian Origin)
    (2004)
  • 3rd Place: Basic Science Research at the Young Investigators Molecular Cardiovascular Forum: Pathways to Cardiac Development and Regeneration (Sponsored by UT Southwestern Medical Center)
    (2003)
  • Diplomate in Cardiovascular Medicine (American Board of Internal Medicine)
    (2002)
  • Above and Beyond the Call of Duty Award
    Recognition for compassionate care (U. of Iowa Hospitals & Clinics) (1998)
  • Diplomate in Internal Medicine (American Board of Internal Medicine)
    (1998)
  • Ernest O. Theilen Award
    Outstanding Cardiac Care Unit Resident of the Year (U. of Iowa Hospitals & Clinics) (1998)

Professional Associations/Affiliations

  • American Society for Biochemistry and Molecular Biology (2008)
  • Central Society for Clinical Research (2008)
  • American College of Cardiology (2004)
  • American College of Physicians (2004)
  • American Heart Association (2004)
  • Dallas County Medical Society (2004)
  • Heart Failure Society of America (2004)
  • International Society of Heart and Lung Transplantation (2004)
  • Texas Medical Association (2004)