Weina Chen, M.D., Ph.D.
Director, Hematopathology; Co-director, Flow Cytometry; Medical Director, Hematology and Hematopathology Lab, UT Southwestern University Hospitals
Professor

Medical School

Shanghai Medical University (1985)

Other Post Graduate Training

Shanghai Medical University (1988)

Graduate School

Shanghai Medical University (1988), Clinical Pharmacology

Other Post Graduate Training

Ecole Polytechnique (1993)

Graduate School

Ecole Polytechnique (1993), Biophysics

Fellowship

National Institute of Environmental Health Science (1995), Research

Fellowship

Duke University Medical Center (1998), Research

Residency

UT Southwestern Medical Center (2002), Anatomic & Clinical Pathology

Fellowship

UT Southwestern Medical Center (2004), Hematopathology

• Flow Cytometry
• Hematopathology (Leukemias and lymphomas)

Featured Publications

MYC protein expression does not correlate with MYC abnormalities detected by FISH but predicts an unfavorable prognosis in de novo acute myeloid leukemia.

Chen P, Redd L, Schmidt Y, Koduru P, Fuda F, Montgomery-Goecker C, Kumar K, Xu-Monette Z, Young K, Collins R, Chen W, Leuk Res 2021 Jul 106 106584

LILRB1: A Novel Diagnostic B-Cell Marker to Distinguish Neoplastic B Lymphoblasts From Hematogones

Saumell Tutusaus S, Pirruccello E, Fuda F, Churchill H, Chen D, Zhang CC, Chen W, Am J Clin Pathol 2021 Jun

PD1/PD-L1 Expressions in Plasmablastic Lymphoma with Clinicopathological Correlation.

Rosado FG, Coberly J, Gupta A, John G, Naina H, Koduru P, Chen W, Ann Clin Lab Sci 2021 Mar 51 2 174-181

Mixed Phenotype Acute Leukemia, B/Myeloid (Bilineal and Biphenotypic), With t(2;22)(q35;q12);EWSR1-FEV.

Montgomery-Goecker C, Koduru P, Botten G, Xu J, Ghisoli M, Goldman SC, Krueger J, Bhushan V, Fuda F, Chen W, J. Pediatr. Hematol. Oncol. 2020 Sep

Leukocyte immunoglobulin-like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic differentiation.

Churchill HRO, Fuda FS, Xu J, Deng M, Zhang CC, An Z, Zhang N, Chen P, Bergstrom C, Kansagra A, Collins R, John S, Koduru P, Chen W, Cytometry B Clin Cytom 2020 Sep

Myeloid diseases in the lung and pleura.

Khoury JD, Chen W, Semin Diagn Pathol 2020 Jun

Flow Cytometric Features in Double/Triple Hit Lymphomas: Dim CD45 Expression of Limited Diagnostic Utility.

Xu X, Fuda F, Alsuwaidan A, Jaso J, Chen W, Cytometry B Clin Cytom 2019 Jul 96 4 321-322

Bright CD38 Expression by Flow Cytometric Analysis Is a Biomarker for Double/Triple Hit Lymphomas with a Moderate Sensitivity and High Specificity.

Alsuwaidan A, Pirruccello E, Jaso J, Koduru P, Garcia R, Krueger J, Doucet M, Chaudhry R, Fuda F, Chen W Cytometry B Clin Cytom 2019 Feb

LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.

Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, Wu G, Yu C, John S, Hirayasu K, Nguyen N, Liu X, Huang F, Li L, Deng H, Tang H, Sadek AH, Zhang L, Huang T, Zou Y, Chen B, Zhu H, Arase H, Xia N, Jiang Y, Collins R, You MJ, Homsi J, Unni N, Lewis C, Chen GQ, Fu YX, Liao XC, An Z, Zheng J, Zhang N, Zhang CC Nature 2018 Oct 562 7728 605-609

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.

Agathocleous M, Meacham CE, Burgess RJ, Piskounova E, Zhao Z, Crane GM, Cowin BL, Bruner E, Murphy MM, Chen W, Spangrude GJ, Hu Z, DeBerardinis RJ, Morrison SJ Nature 2017 Aug

 Featured Books

Immunophenotyping by Flow Cytometry for Acute Myeloid Leukemia. In Methods and Protocols in Series Title: Methods in Molecular Biology

Weina Chen, Hung Luu (2016). New York 2016, Springer, Science+Business, LLC

• Dr. Janet Caldwell Memorial Award for Research in Pathology Fellowship (Faculty mentor/Senior author)
  (2016)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2014)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2009)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2008)
• Graduation with Highest Honor, Ph.D in Biophysics, Ecole Polytechnique, France
  (1993)
• Graduation with Honor, MD (ranked 2nd in a class of 300), Shanghai Medical University
  (1985)