Weina Chen, M.D., Ph.D.
Director, Hematopathology; Co-director, Flow Cytometry;
Professor
Department Pathology
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Education
- Medical School
- Shanghai Medical University (1985)
- Other Post Graduate Training
- Shanghai Medical University (1988)
- Graduate School
- Shanghai Medical University (1988), Clinical Pharmacology
- Other Post Graduate Training
- Ecole Polytechnique (1993)
- Graduate School
- Ecole Polytechnique (1993), Biophysics
- Fellowship
- National Institute of Environmental Health Science (1995), Research
- Fellowship
- Duke University Medical Center (1998), Research
- Residency
- UT Southwestern Medical Center (2002), Anatomic & Clinical Pathology
- Fellowship
- UT Southwestern Medical Center (2004), Hematopathology
Research Interest
- Flow Cytometry
- Hematopathology (Leukemias and lymphomas)
Publications
Featured Publications
- Adult mixed phenotype acute leukemia (MPAL): B/myeloid MPALisoMPO is distinct from other MPAL subtypes.
- Weinberg OK, Dennis J, Zia H, Chen P, Chu A, Koduru P, Luu HS, Fuda F, Chen W, Int J Lab Hematol 2022 Nov
- Monkeypox virus: A new etiology for reactive lymphocytes in peripheral blood.
- Neeley J, Glogowski S, Chen W, EJHaem 2022 Nov 3 4 1388-1389
- Distinct mutational and clinicopathologic profiles characterize acute myeloid leukemia with cup-like nuclei.
- Oertling E, Fuda F, Koduru P, Chen M, Weinberg O, Juntilla M, Jaso J, Vusirikala M, Chung S, Geethakumari PR, Madanat YF, Collins R, Gagan J, Chen W, Leuk Res 2022 Nov 124 106995
- Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance.
- Lyu J, Liu Y, Gong L, Chen M, Madanat YF, Zhang Y, Cai F, Gu Z, Cao H, Kaphle P, Kim YJ, Kalkan FN, Stephens H, Dickerson KE, Ni M, Chen W, Patel P, Mims AS, Borate U, Burd A, Cai SF, Yin CC, You MJ, Chung SS, Collins RH, DeBerardinis RJ, Liu X, Xu J, Cancer Discov 2022 Oct
- Genomic profile of TdTpositive MYC/BCL2 rearranged high-grade B-cell lymphoma supporting its diagnosis as mature aggressive lymphoma.
- Hamdan H, Luu L, Opsahl M, Weinberg O, Fuda F, Koduru P, Wilson K, Gagan J, Ramakrishnan Geethakumari P, Collins R, Chen W, Cytometry B Clin Cytom 2022 Sep
- The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms.
- Khoury JD, Solary E, Abla O, Akkari Y, Alaggio R, Apperley JF, Bejar R, Berti E, Busque L, Chan JKC, Chen W, Chen X, Chng WJ, Choi JK, Colmenero I, Coupland SE, Cross NCP, De Jong D, Elghetany MT, Takahashi E, Emile JF, Ferry J, Fogelstrand L, Fontenay M, Germing U, Gujral S, Haferlach T, Harrison C, Hodge JC, Hu S, Jansen JH, Kanagal-Shamanna R, Kantarjian HM, Kratz CP, Li XQ, Lim MS, Loeb K, Loghavi S, Marcogliese A, Meshinchi S, Michaels P, Naresh KN, Natkunam Y, Nejati R, Ott G, Padron E, Patel KP, Patkar N, Picarsic J, Platzbecker U, Roberts I, Schuh A, Sewell W, Siebert R, Tembhare P, Tyner J, Verstovsek S, Wang W, Wood B, Xiao W, Yeung C, Hochhaus A, Leukemia 2022 Jun
- A Combined Biomarker of Bright CD38 and MYC =55% Is Highly Predictive of Double-/Triple-Hit High-Grade B-Cell Lymphoma.
- Alsuwaidan A, Koduru P, Fuda F, Manuel Jaso J, Chen M, Rosado F, Luu HS, Sweed N, Garcia R, Doucet M, Desai NB, Kumar KA, Awan FT, Ramakrishnan Geethakumari P, Chen W, Am J Clin Pathol 2022 May
- SARS-CoV-2 Infection Associated with Aplastic Anemia and Pure Red Cell Aplasia.
- Lee NC, Patel BA, Etra AM, Bat T, Ibrahim IF, Vusirikala M, Chen M, Rosado F, Jaso JM, Young NS, Chen W, Blood Adv 2022 Apr
- Polar/villous lymphocytes in peripheral blood and exclusively intrasinusoidal lymphoma infiltrate in bone marrow: A clue to splenic diffuse red pulp lymphoma.
- Parmley M, Gagan J, Imam M, Chen W, Int J Lab Hematol 2022 Mar
- CSF3R T618I mutated chronic myelomonocytic leukemia: A proliferative subtype with a distinct mutational profile.
- Kwon A, Ibrahim I, Le T, Jaso JM, Weinberg O, Fuda F, Chen W, Leuk Res Rep 2022 17 100323
Books
Featured Books
Immunophenotyping by Flow Cytometry for Acute Myeloid Leukemia. In Methods and Protocols in Series Title: Methods in Molecular Biology
Weina Chen, Hung Luu (2016). New York 2016, Springer, Science+Business, LLC
Extrameullary myeloid sarcoma. In WHO Classification of Tumours Editorial Board. Head and neck tumours
Medeiros LJ, Chen W. (2022). Lyon (France), International Agency for Research on Cancer; 2022. (WHO classification of tumours series, 5th ed.; vol. 9). Available from: https://tumourclassification.iarc.who.int/chapters/52.
Myeloid Sarcoma. In WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print].
Chen W, Medeiros LJ. (2022). Lyon (France), Lyon (France): International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63.
Acute myeloid leukaemia with minimal differentiation. In WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print]
Chen W, Marcogliese AN, Davis KL, et al. (2022). Lyon (France), International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63.
Mixed-phenotype acute leukaemia, B/myeloid. In WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print].
Chen X, Chen W, Tembhare P, et al. (2022). Lyon (France), International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63.
Mixed-phenotype acute leukaemia, T/myeloid. In In: WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print].
Xiao EB, Chen W, Tembhare P, et al (2022). Lyon (France), International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63.
Acute leukaemia of ambiguous lineage with other defined genetic alterations. In WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print]
Xiao EB, Chen W, Chen X, et al (2022). Lyon (France), International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63.
Mixed-phenotype acute leukaemia, rare types. In WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print].
Chen W, Tembhare P, Orgel E, at al. (2022). Lyon (France), International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63
Acute leukaemia of ambiguous lineage, NOS. In WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print].
Chen W, Tembhare P. Chen X, et al (2022). Lyon (France), International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63.
Acute undifferentiated leukaemia. In WHO Classification of Tumours Editorial Board. Haematolymphoid tumours [Internet; beta version ahead of print].
Chen W, Tembhare P, Orgel E, at al. (2022). Lyon (France), International Agency for Research on Cancer; 2022 (WHO classification of tumours series, 5th ed.; vol. 11). Available from: https://tumourclassification.iarc.who.int/chapters/63.
Cutaneous involvement in myeloid neoplasms, including myeloid sarcoma. In WHO Classification of Tumours Editorial Board. Skin tumours [Internet; beta version ahead of print].
Chen W, Medeiros LJ, Venkataraman G, Battistella M. (2023). Lyon (France), International Agency for Research on Cancer; 2023 (WHO classification of tumours series, 5th ed.; vol. 12). Available from: https://tumourclassification.iarc.who.int/chapters/64.
Honors & Awards
- Dr. Janet Caldwell Memorial Award for Research in Pathology Fellowship (Faculty mentor/Senior author)
(2016) - Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
(2014) - Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
(2009) - Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
(2008) - Graduation with Highest Honor, Ph.D in Biophysics, Ecole Polytechnique, France
(1993) - Graduation with Honor, MD (ranked 2nd in a class of 300), Shanghai Medical University
(1985)