Weina Chen, M.D., Ph.D.
Director, Hematopathology; Co-director, Flow Cytometry; Medical Director, Hematology and Hematopathology Lab, UT Southwestern University Hospitals
Professor

Medical School

Shanghai Medical University (1985)

Graduate School

Shanghai Medical University (1988), Clinical Pharmacology

Graduate School

Ecole Polytechnique (1993), Biophysics

Fellowship

National Institute of Environmental Health Science (1995), Research

Fellowship

Duke University Medical Center (1998), Research

Residency

UT Southwestern Medical Center (2002), Anatomic & Clinical Pathology

Fellowship

UT Southwestern Medical Center (2004), Hematopathology

• Flow Cytometry
• Hematopathology (Leukemias and lymphomas)

Featured Publications

Minimal/Measurable Residual Disease Detection in Acute Leukemias by Multiparameter Flow Cytometry.

Fuda F, Chen W Curr Hematol Malig Rep 2018 Nov

LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.

Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L, Chen Y, Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, Wu G, Yu C, John S, Hirayasu K, Nguyen N, Liu X, Huang F, Li L, Deng H, Tang H, Sadek AH, Zhang L, Huang T, Zou Y, Chen B, Zhu H, Arase H, Xia N, Jiang Y, Collins R, You MJ, Homsi J, Unni N, Lewis C, Chen GQ, Fu YX, Liao XC, An Z, Zheng J, Zhang N, Zhang CC Nature 2018 Oct 562 7728 605-609

A Novel Anti-LILRB4 CAR-T Cell for the Treatment of Monocytic AML.

John S, Chen H, Deng M, Gui X, Wu G, Chen W, Li Z, Zhang N, An Z, Zhang CC Mol. Ther. 2018 Aug

Cytokeratin-positive primary effusion lymphoma: a diagnostic challenge.

Yamani F, Chen W Br. J. Haematol. 2017 Sep

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.

Agathocleous M, Meacham CE, Burgess RJ, Piskounova E, Zhao Z, Crane GM, Cowin BL, Bruner E, Murphy MM, Chen W, Spangrude GJ, Hu Z, DeBerardinis RJ, Morrison SJ Nature 2017 Aug

Immunophenotyping by Multiparameter Flow Cytometry.

Chen W, Luu HS Methods Mol. Biol. 2017 1633 51-73

Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.

Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC Nat. Med. 2016 Dec

CD25 Expression in B Lymphoblastic Leukemia/Lymphoma Predicts t(9;22)(q34;q11)/Philadelphia Chromosome Translocation (Ph) and Is Associated With Residual Disease in Ph-Negative Patients.

Chen P, Chu A, Zia H, Koduru P, Collins R, Winick N, Fuda F, Chen W Am. J. Clin. Pathol. 2016 Nov 146 5 632-638

Blastic plasmacytoid dendritic cell neoplasm with t(11;19)(q23;p13.3);KMT2A(MLL) rearranged: a diagnostic challenge.

Gehlbach D, Koduru P, John G, Fuda F, Frankel AE, Chen W Br. J. Haematol. 2016 Oct

Increased plasma d-2-hydroxyglutarate in isocitrate dehydrogenase 2-mutated blastic plasmacytoid dendritic cell neoplasm.

Rakheja D, Fuda F, Vandergriff T, Boriack R, Medeiros BC, Frankel AE, Chen W Hum. Pathol. 2015 Feb 46 2 322-6

 Featured Books

Immunophenotyping by Flow Cytometry for Acute Myeloid Leukemia. In Methods and Protocols in Series Title: Methods in Molecular Biology

Weina Chen, Hung Luu (2016). New York 2016, Springer, Science+Business, LLC

• Dr. Janet Caldwell Memorial Award for Research in Pathology Fellowship (Faculty mentor/Senior author)
  (2016)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2014)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2009)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2008)
• Graduation with Highest Honor, Ph.D in Biophysics, Ecole Polytechnique, France
  (1993)
• Graduation with Honor, MD (ranked 2nd in a class of 300), Shanghai Medical University
  (1985)