Weina Chen, M.D., Ph.D.
Director, Hematopathology; Co-director, Flow Cytometry; Medical Director, Hematology and Hematopathology Lab, UT Southwestern University Hospitals
Professor

Medical School

Shanghai Medical University (1985)

Graduate School

Shanghai Medical University (1988), Clinical Pharmacology

Graduate School

Ecole Polytechnique (1993), Biophysics

Fellowship

National Institute of Environmental Health Science (1995), Research

Fellowship

Duke University Medical Center (1998), Research

Residency

UT Southwestern Medical Center (2002), Anatomic & Clinical Pathology

Fellowship

UT Southwestern Medical Center (2004), Hematopathology

• Flow Cytometry
• Hematopathology (Leukemias and lymphomas)

Featured Publications

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.

Agathocleous M, Meacham CE, Burgess RJ, Piskounova E, Zhao Z, Crane GM, Cowin BL, Bruner E, Murphy MM, Chen W, Spangrude GJ, Hu Z, DeBerardinis RJ, Morrison SJ Nature 2017 Aug

Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.

Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC Nat. Med. 2016 Dec

CD25 Expression in B Lymphoblastic Leukemia/Lymphoma Predicts t(9;22)(q34;q11)/Philadelphia Chromosome Translocation (Ph) and Is Associated With Residual Disease in Ph-Negative Patients.

Chen P, Chu A, Zia H, Koduru P, Collins R, Winick N, Fuda F, Chen W Am. J. Clin. Pathol. 2016 Nov 146 5 632-638

Blastic plasmacytoid dendritic cell neoplasm with t(11;19)(q23;p13.3);KMT2A(MLL) rearranged: a diagnostic challenge.

Gehlbach D, Koduru P, John G, Fuda F, Frankel AE, Chen W Br. J. Haematol. 2016 Oct

Increased plasma d-2-hydroxyglutarate in isocitrate dehydrogenase 2-mutated blastic plasmacytoid dendritic cell neoplasm.

Rakheja D, Fuda F, Vandergriff T, Boriack R, Medeiros BC, Frankel AE, Chen W Hum. Pathol. 2015 Feb 46 2 322-6

Immunophenotypic characteristics of breast implant-associated anaplastic large-cell lymphoma by flow cytometry.

Montgomery-Goecker C, Fuda F, Krueger JE, Chen W Cytometry B Clin Cytom 2015 Jan

Acute megakaryoblastic leukemia associated with trisomy 21 demonstrates a distinct immunophenotype.

Wang L, Peters JM, Fuda F, Li L, Karandikar NJ, Koduru P, Wang HY, Chen W Cytometry B Clin Cytom 2014 Oct

The emerging role of d-2-hydroxyglutarate as an oncometabolite in hematolymphoid and central nervous system neoplasms.

Rakheja D, Medeiros LJ, Bevan S, Chen W Front Oncol 2013 3 169

IDH mutations in acute myeloid leukemia.

Rakheja D, Konoplev S, Medeiros LJ, Chen W Hum. Pathol. 2012 Oct 43 10 1541-51

Distinct immunophenotype of early T-cell progenitors in T lymphoblastic leukemia/lymphoma may predict FMS-like tyrosine kinase 3 mutations.

Zaremba CM, Oliver D, Cavalier M, Fuda F, Karandikar NJ, Chen W Ann Diagn Pathol 2012 Jan 16 1 16-20

 Featured Books

Immunophenotyping by Flow Cytometry for Acute Myeloid Leukemia. In Methods and Protocols in Series Title: Methods in Molecular Biology

Weina Chen, Hung Luu (2016). New York 2016, Springer, Science+Business, LLC

• Dr. Janet Caldwell Memorial Award for Research in Pathology Fellowship (Faculty mentor/Senior author)
  (2016)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2014)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2009)
• Dr. Arthur Weinberg UTSW Pathology Resident Research Article Award (Faculty mentor/Senior author)
  (2008)
• Graduation with Highest Honor, Ph.D in Biophysics, Ecole Polytechnique, France
  (1993)
• Graduation with Honor, MD (ranked 2nd in a class of 300), Shanghai Medical University
  (1985)