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Patrick Leavey, M.D.

Patrick Leavey, M.D.

Titles and Appointments

Associate Vice Chair of Research Operations

Professor

Schools
Medical School
Departments
Pediatrics

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Patrick Leavey graduated from the Royal College of Surgeons in Ireland in 1986. He spent 4 years in Ireland as a junior house officer (Internal Medicine and Pediatrics), 2 years at Princess Margaret Hospital in Perth, Western Australia as a pediatric registrar and then came to the US to do his pediatric hematology/oncology fellowship at The Children’s Hospital Denver and University of Colorado Health Sciences Center in 1992. Dr. Leavey worked in the lab of Daniel Ambruso, M.D. for 4 years on projects related to the influence of G-CSF on granulocyte function and the exploration and identification of a novel neutrophil cytosolic protein.

    Dr. Leavey joined the pediatric faculty at UT Southwestern Medical Center in 1998 where he is currently a Professor of Pediatrics and a Pediatric Oncologist at Children’s Health, Children’s Medical Center Dallas and Plano.

    During his years of training Dr. Leavey became a member of the Royal College of Physicians of Ireland, a Fellow of the Royal Australasian College of Physicians and a Diplomate of Child Health from the National University of Ireland. He was granted a Doctorate in Medicine from the National University of Ireland, based on his work in the Ambruso laboratory. He is subspecialty board certified in Pediatric Hematology/Oncology by the American Board of Pediatrics.

    Currently Dr. Leavey holds several leadership positions both regionally and nationally. He is the Associate Vice Chair for Research Operations at the Department of Pediatrics, and the Associate Director for Clinical research for the Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center Dallas. Dr. Leavey is the Immediate Past President of the Active Medical / Dental Staff at Children's Medical Center Dallas and past President of the American Society of Pediatric Hematology/Oncology. At the Children’s Oncology Group (COG), Dr. Leavey was a long-standing member of the Bone Sarcoma Steering Committee up to 2023. Dr. Leavey continues to serve on medical advisory boards for the Children’s Cancer Fund and The Clayton Dabney Foundation. 

    Dr. Leavey hold several key positions in clinical and translational research. He is the co-chair for the COG study AOST2031, a co-investigator for a CPRIT funded study of whole slide imaging in pediatric rhabdomyosarcoma and the principal investigator for a Team Connor Foundation award to study machine learning tools in osteosarcoma. Dr. Leavey is also the site PI for an American Society of Hematology Award, establishing the North Texas Sickle Cell Disease Clinical Trial Unit.

  • Education
    Medical School
    Royal College of Surgeons (1986)
    Internship
    Beaumont Hospital (1987), General Surgery
    Residency
    St. Vincents Hospital - Dublin Ireland (1989), Internal Medicine
    Fellowship
    University of Colorado Health Sciences Center (1996), Pediatric Hematology/oncology
    Residency
    Children's Hospital of Denver (1998), Pediatrics
  • Research Interest
    • Development of advances in therapy for children with sarcoma
    • Development of novel biomarkers for patients with bone and soft tissue sarcoma using advanced imaging, digital histology and automated learning tools
  • Publications
    Molecular Characterization Informs Prognosis in Patients With Localized Ewing Sarcoma: A Report From the Children's Oncology Group
    Gillani R, Shulman DS, DelRocco NJ, Klega K, Han R, Krailo MD, Slack JC, Tanhaemami M, Ward A, Bainer V, Ricker C, Sparks J, Bailey KM, Reed DR, DuBois SG, Leavey P, Mascarenhas L, Grohar PJ, Church AJ, Crompton BD, Janeway KA Journal of Clinical Oncology 2025 Dec 43 3750-3759
    Preoperative Radiotherapy in Patients With Localized Ewing Sarcoma Enrolled on AEWS1031: A Report From the Children's Oncology Group
    Indelicato DJ, Callan AK, Ahmed SK, Krailo M, DelRocco N, Buxton AB, Binitie OT, Christ AB, Kessell S, Chuba PJ, Nadel HR, Pawel BR, Gorlick R, Reed DR, DuBois SG, Janeway KA, Leavey P, Mascarenhas L, Laack NN Pediatric Blood and Cancer 2025 Aug 72
    Factors Associated With Primary Site Local Therapy in Patients With Nonmetastatic Ewing Sarcoma Treated With Interval-Compressed Chemotherapy: A Report From the Children’s Oncology Group
    Ahmed SK, Binitie O, Krailo M, Indelicato DJ, Callan AK, DelRocco N, Buxton A, Chuba P, Christ A, Randall RL, Nadel H, Pawel B, Reed DR, Gorlick RG, DuBois SG, Janeway KA, Leavey PJ, Mascarenhas L, Laack NN International Journal of Radiation Oncology Biology Physics 2025 125 521-529
    COVID-19 mRNA vaccination responses in individuals with sickle cell disease: An ASH RC Sickle Cell Research Network Study
    Anderson AR, Strouse JJ, Manwani D, Brandow AM, Vichinsky E, Campbell A, Leavey PJ, Nero A, Ibrahim IF, Field JJ, Baer A, Soto-Calderon H, Vincent L, Zhao Y, Santos JJ, Hensley SE, Mortier N, Lanzkron S, Neuberg D, Abrams CS, Andemariam B, Brandow A, Cohen A, Darbari D, Rassi FE, Field J, Fung E, Gee B, Ibrahim I, Idowu M, Kanter J, Klings ES, King A, Kutlar A, Lebensburger JD, Leavey P, Liem RI, Narang S, Pace B, Quinn CT, Rivlin K, Thompson AA, Tubman VN, Walters M Blood Advances 2024 Sep 8 4549-4553
    Machine Learning for Rhabdomyosarcoma Whole Slide Images Sub-type Classification
    Yadav A, Daescu O, Leavey P, Rudzinski E 2023 Jul 192-196
    Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research
    Yang DM, Zhou Q, Furman-Cline L, Cheng X, Luo D, Lai H, Li Y, Jin KW, Yao B, Leavey PJ, Rakheja D, Lo T, Hall D, Barkauskas DA, Shulman DS, Janeway K, Khanna C, Gorlick R, Menzies C, Zhan X, Xiao G, Skapek SX, Xu L, Klesse LJ, Crompton BD, Xie Y JCO Clinical Cancer Informatics 2023 7
    An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma
    Shulman DS, Whittle SB, Surdez D, Bailey KM, de Álava E, Yustein JT, Shlien A, Hayashi M, Bishop AJ, Crompton BD, DuBois SG, Shukla N, Leavey PJ, Lessnick SL, Kovar H, Delattre O, Grünewald TG, Antonescu CR, Roberts RD, Toretsky JA, Tirode F, Gorlick R, Janeway KA, Reed D, Lawlor ER, Grohar PJ npj Precision Oncology 2022 Dec 6
    Enhancing access to and diversity in cancer clinical trials through a financial reimbursement program: Protocol to evaluate a novel program
    Gerber DE, Tiro JA, McNeill LH, Williams EL, Zhu H, Lee SJ, Leavey PJ, Sadeghi N, Kapinos KA, Dornsife DL, Nguyen V, Wileyto EP, Guerra CE Contemporary Clinical Trials 2022 Oct 121
    Deep Learning of Rhabdomyosarcoma Pathology Images for Classification and Survival Outcome Prediction
    Zhang X, Wang S, Rudzinski ER, Agarwal S, Rong R, Barkauskas DA, Daescu O, Furman Cline L, Venkatramani R, Xie Y, Xiao G, Leavey P American Journal of Pathology 2022 Jun 192 917-925
    Reply to J.-G. Wang et al
    Leavey PJ, Krailo MD, Dubois SG, Reed DR, Janeway KA, Mascarenhas L Journal of Clinical Oncology 2022 May 40 1507-1508
  • Books

    Featured 

  • Honors & Awards
    • UT Southwestern Annual Leaders in Clinical Excellence, Program Development Award (nominee)
      (2021-2022)
    • DFWHC Foundation, Dallas Physician of the Year (nominee)
      Sponsored by Children's Health, Children's Medical Center Dallas (2020)
    • Physician of the Year
      Children's Health, Children's Medical Center Dallas (2020)
    • Best Pediatric Specialists/Doctors in Dallas
      D Magazine (2010-2023)
    • Faculty Teaching Award
      UT Southwestern and Children's Medical Center (2009)
    • Medical Achievement Award
      Little Mo Award - awarded by Wipe out Kids Cancer (2008)
    • Elected to the Society for Pediatric Research
      (2006)
    • Achievement Award
      Gift of Giving Back Award; first such award given by the Clayton Dabney Foundation for Kids with Cancer (2005)
  • Professional Associations/Affiliations
    • American Society of Clinical Oncology (2012)
    • American Society of Pediatric Hematology/Oncology (2004)
    • Children's Oncology Group (2002)
    • Connective Tissue Oncology Society
    • Dallas County Medical Society and Texas Medical Association
    • Society for Pediatric Research (2006)