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Lina Chalak, M.D.

Lina Chalak, M.D.

Chief, Division of Neonatal-perinatal Medicine

Professor & Division Chief

Endowed Title
The William Buchanan Chair in Pediatrics
School
Medical School
Department
Pediatrics | Psychiatry

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Lina Chalak, M.D., M.S.C.S., is a Professor in the Departments of Pediatrics and Psychiatry at UT Southwestern Medical Center. She is the founding director of the Neurointensive Care program and of the Fetal Neonatal Neurology Fellowship Program. Board certified in general pediatrics, general pediatrics recertification, neonatal-perinatal medicine, and neonatal-perinatal recertification, Dr. Chalak joined the UT Southwestern faculty in 2008. 

    Dr. Chalak earned her medical degree and completed a residency in pediatrics at American University of Beirut. She subsequently completed fellowships in both neonatal-perinatal medicine and pediatrics at UT Southwestern/Children’s Health Dallas. In 2011, she received a Master of Clinical Science Distinction from UT Southwestern’s Graduate School of Biomedical Sciences.  

    An active physician-scientist, Dr. Chalak’s research focuses on asphyxia, hypothermia, and neonatal brain injury. The recipient of multiple federally funded awards, her current projects include: cerebrovascular autoregulation and neuronal biomarkers in HIE, as well as neuronal and inflammatory biomarkers involved in neuronal injury pathways. She has led the PRIME mild asphyxia collaborative study and pioneered a “Neurovascular bundle” for a critical real time evaluation of the coupling of cerebral blood flow and neuronal activity in newborns with asphyxia She leads a multi-science research team of physiologists, biomedical engineers with a novel neurovascular bundle for evaluation of the coupling of cerebral blood flow and neuronal activity. She serves on NIH sections, American Pediatric Society (APS) and society of pediatric research SPR executive council. 

     

  • Education
    Medical School
    American University - Beirut (1995)
    Internship
    American University of Beruit (1996), Pediatrics
    Residency
    American University of Beruit (1998), Pediatrics
    Fellowship
    UT Southwestern Medical Center (2001), Neonatal-perinatal Medicine
    Internship
    Children's Medical Center Dallas (2002), Pediatrics
    Residency
    Children's Medical Center Dallas (2004), Pediatrics
    Other Post Graduate Training
    UT Southwestern Medical Center (2011)
    Graduate School
    UT Southwestern Medical Center (2011)
  • Research Interest
    • Asphyxia
    • Hypothermia
    • Neonatal brain injury
  • Publications
    Moving the Needle in Perinatal Asphyxia
    Chalak LF Clinics in Perinatology 2024 Sep 51 xxi-xxiii
    Reverse Therapy: Impact of Hyperthermia and Rewarming on Newborn Outcomes
    Chalak LF, Davidson JO, Gunn AJ Clinics in Perinatology 2024 Sep 51 565-572
    Key Inflammatory Biomarkers in Perinatal Asphyxia: A Comprehensive Review
    Bitar L, Stonestreet BS, Chalak LF Clinics in Perinatology 2024 Sep 51 617-628
    Prognostic value of quantitative EEG in early hours of life for neonatal encephalopathy and neurodevelopmental outcomes
    Kota S, Kang S, Liu YL, Liu H, Montazeri S, Vanhatalo S, Chalak LF Pediatric Research 2024 Aug 96 685-694
    Perinatal asphyxia impact on networks of cortical activity
    Kota S, Chalak L Pediatric Research 2024 Jul 96 17-18
    Postnatal Cerebral Hemodynamics and Placental Vascular Malperfusion Lesions in Neonates With Congenital Heart Disease
    Leon RL, Bitar L, Sharma K, Mir IN, Chalak LF Pediatric Neurology 2024 Jul 156 72-78
    Association between decreased cord blood inter-alpha inhibitor levels and neonatal encephalopathy at birth
    Bitar L, Stonestreet BS, Lim YP, Qiu J, Chen X, Mir IN, Chalak LF Early Human Development 2024 Jun 193
    Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial
    Author Collaboration HT, Mietzsch U, Kolnik SE, Wood TR, Natarajan N, Gonzalez FF, Glass H, Mayock DE, Bonifacio SL, Van Meurs K, Comstock BA, Heagerty PJ, Wu TW, Wu YW, Juul SE, Ahmad KA, Baserga M, Bendel-Stenzel E, Benninger KL, Chalak L, Chang T, Flibotte J, Lampland AL, Maitre NL, Mathur AM, Merhar S, Poindexter BB, Rao R, Riley D, Smyser CD, Sokol GM, Weitkamp JH, Yanowitz T Archives of Disease in Childhood: Fetal and Neonatal Edition 2024 May 109 308-316
    Development of neonatal connectome dynamics and its prediction for cognitive and language outcomes at age 2
    Xu Y, Liao X, Lei T, Cao M, Zhao J, Zhang J, Zhao T, Li Q, Jeon T, Ouyang M, Chalak L, Rollins N, Huang H, He Y Cerebral Cortex 2024 May 34
    Genetic and Congenital Anomalies in Infants With Hypoxic-Ischemic Encephalopathy
    Morell AS, Monsell SE, Cornet MC, Wisnowski JL, McKinstry RC, Mathur AM, Li Y, Glass HC, Gonzalez FF, Mayock DE, Benninger KL, Van Meurs KP, Lampland AL, Wu TW, Riley D, Mietzsch U, Chalak L, Flibotte J, Weitkamp JH, Ahmad KA, Yanowitz TD, Baserga M, Merhar S, Rao R, Sokol GM, Comstock BA, Heagerty PJ, Juul SE, Wu YW Pediatric Neurology 2024 May 154 44-50
  • Honors & Awards
    • Executive Leadership
      Executive Leadership in Academic Medicine (2023)
    • Executive Council Society of Pediatric Research
      (2020)
    • Program Development Award Nomination Fetal/Neonatal Neurological Program
      UT Southwestern Medical Center-Leaders in Clinical Excellence (2020)
    • Acarin Award for Outstanding Presentation
      10th Hershey Conference Equivilly, France (2016)
    • Elected member, International Perinatal Collegium
      (2015)
    • Elected member, The Perinatal Research Society
      (2014)
    • Elected member, Society of Pediatric Research
      (2011)
    • PRS Young Research Investigator Award
      Perinatal Research Society (2010)
    • Dean's Teaching Award for Education
      Department of Pediatrics at the University of Arkansas, Little Rock, AR (2007-2008)
    • Best Teacher Award
      Department of Pediatrics at the University of Arkansas, Little Rock, AR (2006-2007)
    • Educator of the Year
      Department of Pediatrics at the University of Arkansas, Little Rock, AR (2005-2006)
    • AAP Young Investigator Award
      AAP (2004)
  • Professional Associations/Affiliations
    • American Pediatric Society (2019)
    • International Perinatal Collegium (2015)
    • Newborn Brain Society (2019)
    • Perinatal Research Society (2014)
    • Society for Pediatric Research (2011)
    • SPR Executive Council-Lead for Education and Scientific Programs (2020)