Medical School
American University - Beirut (1995)
American University of Beruit (1996), Pediatrics
American University of Beruit (1998), Pediatrics
UT Southwestern Medical Center (2001), Neonatal-perinatal Medicine
Children's Health Dallas (2002), Pediatrics
Children's Health Dallas (2004), Pediatrics
Graduate School
UT Southwestern Medical Center (2011)
Other Post Graduate Training
UT Southwestern Medical Center (2011)

Research Interest

  • Asphyxia
  • Hypothermia
  • Neonatal brain injury


Featured Publications LegendFeatured Publications

Structural network maturation of the preterm human brain.
Zhao T, Mishra V, Jeon T, Ouyang M, Peng Q, Chalak L, Wisnowski JL, Heyne R, Rollins N, Shu N, Huang H, Neuroimage 2019 01 185 699-710
Brain imaging in preterm infants <32 weeks gestation: a clinical review and algorithm for the use of cranial ultrasound and qualitative brain MRI.
Ibrahim J, Mir I, Chalak L Pediatr. Res. 2018 Oct
Prospective research in infants with mild encephalopathy identified in the first six hours of life: neurodevelopmental outcomes at 18-22 months.
Chalak LF, Nguyen KA, Prempunpong C, Heyne R, Thayyil S, Shankaran S, Laptook AR, Rollins N, Pappas A, Koclas L, Shah B, Montaldo P, Techasaensiri B, Sánchez PJ, Sant'Anna G Pediatr. Res. 2018 Sep
Fetal-placental crosstalk occurs through fetal cytokine synthesis and placental clearance.
Mir IN, Chalak LF, Liao J, Johnson-Welch S, Brown LS, Longoria C, Savani RC, Rosenfeld CR Placenta 2018 Sep 69 1-8
Lenticulostriate vasculopathy in preterm infants: a new classification, clinical associations and neurodevelopmental outcome.
Sisman J, Chalak L, Heyne R, Pritchard M, Weakley D, Brown LS, Rosenfeld CR J Perinatol 2018 Aug
Age-specific gray and white matter DTI atlas for human brain at 33, 36 and 39 postmenstrual weeks.
Feng L, Li H, Oishi K, Mishra V, Song L, Peng Q, Ouyang M, Wang J, Slinger M, Jeon T, Lee L, Heyne R, Chalak L, Peng Y, Liu S, Huang H Neuroimage 2018 Jun
A review of the conundrum of mild hypoxic-ischemic encephalopathy: Current challenges and moving forward.
Chalak L, Latremouille S, Mir I, Sánchez PJ, Sant'Anna G, Early Hum. Dev. 2018 05 120 88-94
Future alternative therapies in the pipeline for mild neonatal encephalopathy: Review of evidence of neuroprotection with erythropoiesis stimulating agents.
DuPont T, Chalak L, Early Hum. Dev. 2018 05 120 95-98
Best practice guidelines on management of mild neonatal encephalopathy: Is it really mild?
Chalak LF Early Hum. Dev. 2018 Feb
Prospective research on infants with mild encephalopathy: the PRIME study.
Prempunpong C, Chalak LF, Garfinkle J, Shah B, Kalra V, Rollins N, Boyle R, Nguyen KA, Mir I, Pappas A, Montaldo P, Thayyil S, Sánchez PJ, Shankaran S, Laptook AR, Sant'Anna G J Perinatol 2017 Nov

Honors & Awards

  • Elected member, Society of Pediatric Research
  • PRS Young Research Investigator Award
    Perinatal Research Society (2010)

Professional Associations/Affiliations

  • International Perinatal Collegium (2015)
  • Perinatal Research Society (2014)
  • Society for Pediatric Research (2011)