Education

Medical School
American University - Beirut (1995)
Internship
American University of Beruit (1996), Pediatrics
Residency
American University of Beruit (1998), Pediatrics
Fellowship
UT Southwestern Medical Center (2001), Neonatal-perinatal Medicine
Internship
Children's Health Dallas (2002), Pediatrics
Residency
Children's Health Dallas (2004), Pediatrics

Research Interest

  • neonatal brain injury, asphyxia, hypothermia

Publications

Featured Publications LegendFeatured Publications

Impairment of cerebral autoregulation in pediatric extracorporeal membrane oxygenation associated with neuroimaging abnormalities.
Tian F, Morriss MC, Chalak L, Venkataraman R, Ahn C, Liu H, Raman L Neurophotonics 2017 Oct 4 4 041410
Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
Laptook AR, Shankaran S, Tyson JE, Munoz B, Bell EF, Goldberg RN, Parikh NA, Ambalavanan N, Pedroza C, Pappas A, Das A, Chaudhary AS, Ehrenkranz RA, Hensman AM, Van Meurs KP, Chalak LF, Hamrick SEG, Sokol GM, Walsh MC, Poindexter BB, Faix RG, Watterberg KL, Frantz ID, Guillet R, Devaskar U, Truog WE, Chock VY, Wyckoff MH, McGowan EC, Carlton DP, Harmon HM, Brumbaugh JE, Cotten CM, Sánchez PJ, Hibbs AM, Higgins RD JAMA 2017 10 318 16 1550-1560
Effect of Depth and Duration of Cooling on Death or Disability at Age 18 Months Among Neonates With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Huitema CMP, Grisby C, Devaskar U, Ehrenkranz RA, Harmon HM, Chalak LF, DeMauro SB, Garg M, Hartley-McAndrew ME, Khan AM, Walsh MC, Ambalavanan N, Brumbaugh JE, Watterberg KL, Shepherd EG, Hamrick SEG, Barks J, Cotten CM, Kilbride HW, Higgins RD JAMA 2017 Jul 318 1 57-67
Novel Wavelet Real Time Analysis of Neurovascular Coupling in Neonatal Encephalopathy.
Chalak LF, Tian F, Adams-Huet B, Vasil D, Laptook A, Tarumi T, Zhang R Sci Rep 2017 Apr 7 45958
New Wavelet Neurovascular Bundle for Bedside Evaluation of Cerebral Autoregulation and Neurovascular Coupling in Newborns with Hypoxic-Ischemic Encephalopathy.
Chalak LF, Zhang R Dev. Neurosci. 2017 Mar
Heterogeneous increases of regional cerebral blood flow during preterm brain development: Preliminary assessment with pseudo-continuous arterial spin labeled perfusion MRI.
Ouyang M, Liu P, Jeon T, Chalak L, Heyne R, Rollins NK, Licht DJ, Detre JA, Roberts TP, Lu H, Huang H Neuroimage 2016 Dec 147 233-242
Inflammatory Biomarkers of Birth Asphyxia.
Chalak LF Clin Perinatol 2016 Sep 43 3 501-10
Genetic diversity in barley landraces (Hordeum vulgare L. subsp.vulgare) originated from Crescent Fertile region as detected by seed storage proteins.
Mzid R, Chibani F, Ayed RB, Hanana M, Breidi J, Kabalan R, El-Hajj S, Machlab H, Rebai A, Chalak L J. Genet. 2016 Sep 95 3 733-9
Hypothermia for neonatal hypoxic-ischemic encephalopathy: NICHD Neonatal Research Network contribution to the field.
Shankaran S, Natarajan G, Chalak L, Pappas A, McDonald SA, Laptook AR Semin. Perinatol. 2016 Jun
Early Development of Functional Network Segregation Revealed by Connectomic Analysis of the Preterm Human Brain.
Cao M, He Y, Dai Z, Liao X, Jeon T, Ouyang M, Chalak L, Bi Y, Rollins N, Dong Q, Huang H Cereb. Cortex 2016 Mar

Honors & Awards

  • Elected member, Society of Pediatric Research
    (2011)
  • PRS Young Research Investigator Award
    Perinatal Research Society (2010)

Professional Associations/Affiliations

  • International Perinatal Collegium (2015)
  • Perinatal Research Society (2014)
  • Society for Pediatric Research (2011)