Dr. DeBose-Boyd was born and raised in a small rural southeastern Oklahoma community (population 700) where he graduated from Boswell High School, Boswell, Oklahoma in 1989. Soon thereafter, he began undergraduate studies at Southeastern Oklahoma State University (SOSU) in Durant, OK, where he participated in the Minority Biomedical Research Support program.Dr. DeBose-Boyd obtained a Bachelor of Science degree in Chemistry with minors in Mathematics and Biology in 1993.
Upon completion of undergraduate studies, he was accepted into the Department of Biochemistry and Molecular Biology at the University of Oklahoma Health Sciences Center, and joined the laboratory of Richard D. Cummings, PhD. In 1998, he successfully defended his thesis, entitled "Identification, characterization, and molecular cloning of alpha 1,3 fucosyltransferases in parasitic and non-parasitic helminths."
Following his defense, Dr. DeBose-Boyd joined the laboratory of Joseph L. Goldstein, M.D. and Michael S. Brown, M.D. at UT Southwestern as a fellow of the Jane Coffin Childs Memorial Fund for Medical Research. Dr. DeBose-Boyd is married to Gwendolyn and has two sons, Reginald and Ryan.
- Southeastern Oklahoma St Univ (1993), Chemistry
- Graduate School
- Uni of Oklahoma-Hlth Sci Ctr (1998), Biochemistry
- Cell Regulation
- Cholesterol homeostasis
- Endoplasmic Reticulum Associated Degradation
- Multivalent feedback regulation of HMG CoA reductase
- Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.
- Nguyen AD, Lee SH, DeBose-Boyd RA J. Biol. Chem. 2009 Sep 284 39 26778-88
Honors & Awards
- Early Career Scientist Award, Howard Hughes Medical Institute
- W.M. Keck Distinguished Young Scholar in Medical Research
- David L. Williams Memorial Lectureship Award
- Established Investigator of American Heart Association
- Fellow of The Jane Coffin Childs Memorial Fund for Medical Research