Mark Agostini, M.D.

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Mark Agostini, M.D., is a Professor of Neurology at UT Southwestern Medical Center. He specializes in the care of patients with epilepsy. 

Dr. Agostini received his medical degree at Harvard Medical School and completed his neurology residency at Massachusetts General Hospital, a teaching affiliate of Harvard Medical School. He completed a fellowship in neurology at the UCLA School of Medicine. He has been a member of the U.T. Southwestern's Department of Neurology since 1997. He is certified by the American Board of Psychiatry & Neurology in Neurology and Epilepsy. Since 2014 he has been the Medical Director for the Parkland Memorial Hospital EMU and EEG Laboratory 

Dr. Agostini is active in clinical research, patient care and the education of medical students, neurology residents and neurology fellows. He is the Principal Investigator (PI) of an ongoing study of the clinical effects of an intracranial neurostimulator, used in the treatment of patients with difficult to control epilepsy. He is also active in the research regarding the outcomes of patients presented to the Parkland Hospital ED with seizures, the assessment of bedside seizure testing by nurses, the occurrence of missed seizures in an EMU, the clinical significance of perodic EEG patterns and various aspects of using intracranial EEG in the presurgical evaluation of patients with intractable epilepsy. 

Dr. Agostini has received many awards for education including the A.B. Baker Teacher Recognition Certificate from the American Academy of Neurology and The University of Texas Regents' Outstanding Teaching Award. He, along with Dr. Richard Dewey, Jr., initiated the U.T. Southwestern core clerkship in Neurology in 2005 and served as the clerkship director until 2018. He continues to work as an assistant clerkship director. He created  and continues to manage the "D2L-Desire To Learn", online teaching website for neurology core clerkship students. 

Medical School

Harvard Medical School (1989)

Internship

Massachusetts General Hospital (1990), Medicine

Residency

Massachusetts General Hospital (1993), Neurology

Fellowship

Instituto Scientifico San Raffaela Hospital (1995), Neurophysiology

Fellowship

UCLA (1997), Epilepsy/eeg

• Clinical Correlates of Periodic EEG Patterns
• Emergency Department Treatment and Outcomes In Patients Presenting With Seizures
• Evaluation of Bedside Seizure Testing By Nursing Staff
• Evaluation of Missed Seizures In An EMU

Featured Publications

Emergency department visits and readmissions in patients with psychogenic nonepileptic seizures (PNES) at a safety net hospital.

Ramamurthy S, Steven Brown L, Agostini M, Alick Lindstorm S, Dave H, Dieppa M, Ding K, Doyle A, Hays R, Harvey J, Perven G, Podkorytova I, Zepeda R, Das RR, Epilepsy Behav 2021 Aug 122 108225

Emergent Admissions to the Epilepsy Monitoring Unit in the Setting of COVID-19 Pandemic-related, State-mandated Restrictions: Clinical Decision Making and Outcomes.

Zepeda R, Lee Y, Agostini M, Alick Lindstrom S, Dave H, Dieppa M, Ding K, Doyle A, Harvey J, Hays R, Perven G, Podkorytova I, Das RR, Neurodiagn J 2021 Jun 61 2 95-103

Physical activity status and quality of life in patients with epilepsy - Survey from level four epilepsy monitoring units.

Green R, Abe C, Denney DA, Zhang R, Doyle A, Gadelmola K, Cullum CM, Simon J, Neaves S, Perven G, Dieppa M, Hays R, Agostini M, Ding K, Epilepsy Res 2021 Apr 173 106639

Non-lesional mesial temporal lobe epilepsy requires bilateral invasive evaluation.

Perven G, Podkorytova I, Ding K, Agostini M, Alick S, Das R, Dave H, Dieppa M, Doyle A, Harvey J, Lega B, Zepeda R, Hays R, Epilepsy Behav Rep 2021 15 100441

Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy.

Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ, Neurology 2020 Jul

Invasion of microglia/macrophages and granulocytes into the Mauthner axon myelin sheath following spinal cord injury of the adult goldfish, Carassius auratus.

Koganti L, Liu J, DeMajewski A, Agostini MA, Wong TW, Faber DS, Zottoli SJ, J. Morphol. 2019 Nov

Comparison of psychiatric comorbidities and impact on quality of life in patients with epilepsy or psychogenic nonepileptic spells.

Abe C, Denney D, Doyle A, Cullum M, Adams J, Perven G, Dave H, Dieppa M, Hays R, Agostini M, Ding K, Epilepsy Behav 2019 Nov 102 106649

Treatment of drug-resistant epilepsy in patients with periventricular nodular heterotopia using RNS® System: Efficacy and description of chronic electrophysiological recordings.

Nune G, Arcot Desai S, Razavi B, Agostini MA, Bergey GK, Herekar AA, Hirsch LJ, Lee RW, Rutecki PA, Srinivasan S, Van Ness PC, Tcheng TK, Morrell MJ, Clin Neurophysiol 2019 May 130 8 1196-1207

Diagnostic Yield of 2-Hour EEG Is Similar With 30-Minute EEG in Patients With a Normal 30-Minute EEG.

Mahuwala Z, Ahmadi S, Bozoky Z, Hays R, Agostini M, Ding K, J Clin Neurophysiol 2019 Feb

Neurological Autoantibody Prevalence in Epilepsy of Unknown Etiology.

Dubey D, Alqallaf A, Hays R, Freeman M, Chen K, Ding K, Agostini M, Vernino S JAMA Neurol 2017 Feb

 Featured Books

Noninvasive Monitoring. In Neurotrauma and Critical Care of the Brain

Rubin M, Agostini MA, Madden CJ. (2009). New York, N.Y., Thieme Medical Publishers, Inc.

• Graduation Marshall
  Selected by the UTSW graduating class (2018)
• Graduation Marshall
  Selected by the UTSW graduating class (2017)
• Selected as Keynote Speaker, Class of 2017 Senior Banquet
  U.T. Southwestern Medical Center (2017)
• Graduation Marshall
  Selected by the UTSW graduating class (2016)
• Alpha Omega Alpha Honor Medical Society
  In recognition of medical student teaching. U.T. Southwestern Medical Center (2015)
• Graduation Marshall
  Selected by the UTSW graduating class (2015)
• Designated as a Distinguished Teaching Professor
  U.T. Southwestern Medical Center (2014)
• Regents' Outstanding Teaching Award
  Medical student teaching award given by the University of Texas (2014)
• Graduation Marshall
  Selected by the UTSW graduating class (2013)
• Outstanding Teaching Award. MS2 Class
  Medical Student Teaching Award. U.T. Southwestern Medical Center (2010)
• Outstanding Adult Neurology Faculty Teaching Award
  Clinical Neurology Teaching Award. UTSW Department of Neurology & Neurotherapeutics (2009)
• Outstanding Adult Neurology Faculty Teaching Award
  Selected by Pediatric Residents. Department of Neurology & Neurotherapeutics (2009)
• A.B. Baker Teacher Recognition Certificate. American Academy of Neurology
  In recognition of outstanding teachers in neurology (2008)
• Socrates Award. Class of 2007 and 2008
  Medical Student Teaching Award. U.T. Southwestern Medical Center (2007)
• Clinical Teaching Award. Neurology Clerkship Class of 2006
  Medical Student Teaching Award. U.T. Southwestern Medical Center (2006)
• Oustanding Adult Neurology Faculty Teaching Award
  Clinical Neurology Teaching Award. UTSW Department of Neurology & Neurotherapeutics (2005)
• Pre-Clinical Teaching Award Class of 2009
  Medical Student Teaching Award. U.T. Southwestern School of Medicine (2005)
• PreClinical Teaching Award. Class of 2009
  Medical Student Teaching Award. U.T. Southwestern Medical Center (2005)
• Outstanding Faculty Teaching Award
  Clinical Teaching Award. UTSW Department of Neurology & Neurotherapeutics (2000)
• Outstanding Resident Teaching Award
  Clinical Teaching Award. U.C.L.A. Department of Neurology (1997)
• Glaxo Young Investigator Award
  (1996)
• Topscholar Award
  (1996)
• Merritt-Putnam Award
  (1995)
• Phi Beta Kappa
  Amherst College (1980)

• American Academy of Neurology (1997)
• Department of Neurology & Neurotherapeutics, U.T. Southwestern Medical Center (1997)
• Parkland Memorial Hospital (1997)
• Professional Advisory Board Epilepsy Foundation, Greater North Texas (1997)
• Zale Lipshy University Hospital (1997)