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Yu-Guang He, M.D.

Yu-Guang He, M.D.

Titles and Appointments

Professor

Endowed Title
Josephine Long Biddle Chair in Age-Related Macular Degeneration Research; Zora Meagher Macular Degeneration Research Professorship
School
Medical School
Department
Ophthalmology

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  • Biography

    Dr. Yu-Guang He joined the Department of Ophthalmology as an Assistant Professor in 2001. In 2006, he became the first holder of the Zora Meagher Macular Degeneration Research Professoship in the Department of Ophthalmology and in 2011 he was named the Josephine Long Biddle Chair in Age-Related Macular Degeneration Research.

    Prior to joining UT Southwestern, he completed a vitro-retinal surgery fellowship at the University of Washington School of Medicine in Seattle. He attended medical school at Tongi Medical University in Wuhan, China, and did his residency at UT Southwestern. His research interests are ocular-epithelial cell transplantation and ocular immunology. Dr. He received first place for his scientific paper presentation at the 1992 CLAO Annual Meeting. In 1999 and 2001, he received the Resident and Fellow Research Forum Presenter Award from the Association of University Professors of Ophthalmologists. In addition, he received the James A.Shannon Directors Award from the National Institutes of Health in 1995.

  • Education
    Medical School
    Tongji Medical University (1982)
    Residency
    Tongii Medical University (1988), Ophthalmology
    Fellowship
    UT Southwestern Medical School (1990), Cornea Service
    Internship
    UT Southwestern Medical School (1996), Transitional Year
    Residency
    UT Southwestern Medical School (1999), Ophthalmology
    Fellowship
    University of Washington Affiliated Hospitals (2001), Vitreoretinal
  • Research Interest
    • Ocular cell biology
    • Ocular immunology
    • Transplantation of RPE cells
  • Publications
    Outcomes and Need for Additional Interventions after Intravitreal Bevacizumab for Retinopathy of Prematurity
    Sun AJ, Garcia BY, Patrick H, He YG, Wang AL Ophthalmology Retina 2025 Jun 9 564-569
    Landmark trials in retinal vein occlusion
    Zhou B, He Y 2025 Feb 247-266
    Nonredundant Role of Leishmanolysin-Like (Lmln) Zinc-Metallopeptidase in Retinal Homeostasis
    Ufret-Vincenty RL, Kirman DC, Ulker-Yilmazer G, Aredo B, Shrestha S, Turpin E, Yuksel S, Zegeye Y, Ludwig S, Moresco EM, He YG, Beutler B American journal of ophthalmology 2025 Jan 269 147-160
    E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration
    Zegeye Y, Aredo B, Yuksel S, Kirman DC, Kumar A, Chen B, Turpin E, Shresta S, He YG, Gautron L, Tang M, Li X, DiCesare SM, Hulleman JD, Xing C, Ludwig S, Moresco EM, Beutler BA, Ufret-Vincenty RL Scientific reports 2024 Dec 14
    Atypical Central Serous Chorioretinopathy Masquerading as Vogt-Koyanagi-Harada Disease: A Case Report
    Duran M, Shieh D, Choi P, He YG, Ufret-Vincenty RL Case Reports in Ophthalmology 2024 May 15 441-450
    Impact of COVID-19-related lifestyle changes on diabetic macular edema
    Johnson BP, He YG, Robertson ZM, Wang A, Ufret-Vincenty RL International Journal of Ophthalmology 2023 Jan 17 97-106
    Comparison of Surgical Outcomes for Uncomplicated Primary Retinal Detachment Repair
    Heydinger S, Wang AL, Ufret-Vincenty R, Robertson ZM, He YG Clinical Ophthalmology 2023 17 907-915
    Guideline for the treatment of no light perception eyes induced by mechanical ocular trauma
    Yan H, Yang K, Ma Z, Kuhn F, Zhang W, Wang ZJ, Hu Y, Lu H, Shigeo Y, Sobaci G, Ozdek S, Forlini M, Huang B, Hui Y, Zhang M, Xu G, Wei W, Jiang Y, Park DH, Fernandes RA, He Y, Rousselot A, Hoskin A, Sundar G, Liu Y, Wang Y, Shen L, Chen H, Chen H, Han G, Jiang R, Jin X, Lin J, Luo J, Wang Z, Wei Y, Wen Y, Xie Z, Wang Y, Yang X, Yu W, Zheng Z, Sun X, Liang J, Liu Q, Yu J, Wei S, Li Z, Chen L, Wang X, Wei L, Zhang H, Chen S, Liu Y, Guo X, Liu S, Xu X, Tao Y, Chen Y, Chen Y Journal of Evidence-Based Medicine 2022 Sep 15 302-314
    Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial
    Author Collaboration ft, Adams-Chapman I, Watterberg KL, Nolen TL, Hirsch S, Cole CA, Cotten CM, Oh W, Poindexter BB, Zaterka-Baxter KM, Das A, Lacy CB, Scorsone AM, Duncan AF, DeMauro SB, Goldstein RF, Colaizy TT, Wilson-Costello DE, Purdy IB, Hintz SR, Heyne RJ, Myers GJ, Fuller J, Merhar S, Harmon HM, Peralta-Carcelen M, Kilbride HW, Maitre NL, Vohr BR, Natarajan G, Mintz-Hittner H, Quinn GE, Wallace DK, Olson RJ, Orge FH, Tsui I, Gaynon M, Hutchinson AK, He YG, Winter TW, Yang MB, Haider KM, Cogen MS, Hug D, Bremer DL, Donahue JP, Lucas WR, Phelps DL, Sánchez PJ, Wyckoff MH, Brion LP Journal of Perinatology 2021 Aug 41 2072-2087
    Retinal Hemorrhages During Examination for Retinopathy of Prematurity: A Form of Ocular Decompression Retinopathy
    Matei VM, He YG Journal of VitreoRetinal Diseases 2021 Jan 5 72-76
  • Honors & Awards
    • Texas Monthly Magazine
      Super Doctors (2014)
    • D Magazine
      Best Doctors in Dallas (2013)
    • Endowed Chair
      Josephine Lond Biddle Chair in Age-Related Macular Degeneration Research (2011)
    • Small Business Innovation Research Award (NEI/NIH)
      Validation of a Novel Vision Assessment System (2010)
  • Professional Associations/Affiliations
    • AAO (American Academy of Ophthalmology)
    • ARVO (Assn. for Research in Vision & Ophthalmology)
    • ASRS (American Society of Retina Specialists)
    • TMA (Texas Medical Association)