Yong Du, Ph.D. Titles and Appointments Professor Schools Medical School | Graduate School Departments Radiology | Biomedical Engineering Graduate Programs Biomedical Engineering Biography Dr. Du is a Professor of Radiology in the Medical Physics Division at UT Southwestern Medical Center. He is a certified Nuclear Medicine Physicist by the American Board of Radiology. Dr. Du earned his undergraduate and master's degrees in Biophysics from Nankai University, followed by a master's degree in Applied Physics from East Carolina University. He completed his Ph.D. in Biomedical Engineering at the University of North Carolina at Chapel Hill and went on to complete a postdoctoral fellowship at Johns Hopkins University. Prior to joining UT Southwestern, Dr. Du was a Professor in the Department of Radiology and Radiological Science at the Johns Hopkins University School of Medicine, where he also held a joint appointment at the Sidney Kimmel Comprehensive Cancer Center. As an educator, Dr. Du was one of the founders of the Joint Medical Physics Education Program at Johns Hopkins University and served as the co-director of the Master’s Program in Medical Physics till 2026. Dr. Du’s research focuses on advancing medical imaging physics, with specialized expertise in SPECT and PET imaging, image reconstruction, photon transport simulation and modeling, quantitative image biomarkers, and tracer kinetic modeling. Research Interest Nuclear Medicine Imaging (SPECT and PET) Physics, Reconstruction, and Modeling Quantitative Imaging Biomarkers Radiopharmaceutical Therapy and Image Guided Dosimetry Publications Featured Publications Quantitative Reconstructions for Renal Sestamibi SPECT/CT: A Modeled Comparison of 360-Degree Versus 180-Degree Acquisitions. Oldan JD, Schroeder JA, Jeyasingam M, Solnes LB, Mondragon EL, Benefield T, Allaf ME, Tulchinsky M, Gorin MA, Du Y, Rowe SP, Nuklearmedizin 2026 Aug Beyond the LUMIR challenge: The pathway to foundational registration models. Chen J, Wei S, Honkamaa J, Marttinen P, Zhang H, Liu M, Zhou Y, Tan Z, Wang Z, Wang Y, Zhou H, Hu S, Zhang Y, Tao Q, Förner L, Wendler T, Jian B, Wiestler B, Hable T, Kim J, Ruan D, Madesta F, Sentker T, Heyer W, Zuo L, Dai Y, Wu J, Prince JL, Bai H, Du Y, Liu Y, Hering A, Dorent R, Hansen L, Heinrich MP, Carass A, Med Image Anal 2026 Jun 113 104175 Unsupervised learning of spatially varying regularization for diffeomorphic image registration. Chen J, Wei S, Liu Y, Bian Z, He Y, Carass A, Bai H, Du Y, Med Image Anal 2026 Feb 108 103887 Fluorine-18-labeled PET radiotracers for imaging the macrophage colony-stimulating factor 1 receptor (CSF1R). Das D, Cha H, Naik R, Holt DP, Fan H, Hall A, Lesniak WG, Du Y, Minn I, Dannals RF, Pomper MG, Horti AG, EJNMMI Radiopharm Chem 2026 Jan Deep learning-derived arterial input function for dynamic brain PET. Chen J, Jiang Z, Coughlin JM, Cheong I, Mills KA, Pomper MG, Du Y, Neuroimage 2025 Nov 121609 Artificial intelligence-based lesion characterization and outcome prediction of prostate cancer on [18F]DCFPyL PSMA imaging. Zhao L, Imami MR, Wang Y, Mao Y, Hsu WC, Chen R, Mena E, Li Y, Tang J, Wu J, Voter AF, Amindarolzarbi A, Kargilis D, Afyouni S, Gafita A, Chen J, Chin BB, Leal JP, Du Y, Lin G, Jiao Z, Choyke PL, Rowe SP, Pomper MG, Liao W, Bai HX, Radiother Oncol 2025 Nov 214 111265 A survey on deep learning in medical image registration: New technologies, uncertainty, evaluation metrics, and beyond. Chen J, Liu Y, Wei S, Bian Z, Subramanian S, Carass A, Prince JL, Du Y, Med Image Anal 2025 Feb 100 103385 An Automated Deep Learning-Based Framework for Uptake Segmentation and Classification on PSMA PET/CT Imaging of Patients with Prostate Cancer. Li Y, Imami MR, Zhao L, Amindarolzarbi A, Mena E, Leal J, Chen J, Gafita A, Voter AF, Li X, Du Y, Zhu C, Choyke PL, Zou B, Jiao Z, Rowe SP, Pomper MG, Bai HX, J Imaging Inform Med 2024 Oct 37 5 2206-2215 A radioligand for in vitro autoradiography of CSF1R in post-mortem CNS tissues. Foss CA, Naik R, Das D, Cha H, Minn I, Hall A, Finley P, Wu SJ, Du Y, Dannals RF, Pomper MG, Horti AG, EJNMMI Res 2024 Aug 14 1 76 Hippocampal Availability of the α7 Nicotinic Acetylcholine Receptor in Recent-Onset Psychosis. Wong NR, Rubin LH, Harrington CK, Jenkins KR, Shinehouse LK, Yoon M, Kilgore JJ, Soule AR, Lesniak WG, Rowe SP, Horti AG, Kamath V, Dannals RF, Du Y, Pomper MG, Coughlin JM, JAMA Netw Open 2024 Aug 7 8 e2427163 Results 1-10 of 88 1 2 3 4 5 Next Last Professional Associations/Affiliations American Association of Physicists in Medicine Institute of Electrical and Electronics Engineers Society of Nuclear Medicine and Molecular Imaging
