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Henry De Belly, Ph.D.

Henry De Belly, Ph.D.

Titles and Appointments

Assistant Professor

School
Medical School
Department
Children's Medical Center Research Institute at UT Southwestern | Pediatrics
  • Biography

    Henry De Belly, Ph.D., received a bachelor’s in immunology from the University of Montpellier in France and a master’s in biophysics from Université Paris Diderot. He completed his Ph.D. in stem cell biophysics at University College London, where he investigated the role of mechanical forces in regulating cell fate.

    In 2020, Dr. De Belly joined the laboratory of Orion Weiner, Ph.D., at the University of California, San Francisco. There, he combined cell biology, biophysics, and computational modeling to uncover how mechanical cues act as long-range coordinators to signal and guide immune cell migration. During his training, he received several fellowships, including a Marie Skłodowska-Curie PhD Fellowship, a European Molecular Biology Organization Postdoctoral Fellowship, and the NIH Pathway to Independence Award (K99/R00).

    Dr. De Belly joined the faculty of Children’s Medical Center Research Institute at UT Southwestern in January 2026.

  • Publications

    Star Featured Publications

    Long range mutual activation establishes Rho and Rac polarity during cell migration.
    De Belly H, Gallen AF, Strickland E, Estrada DC, Zager PJ, Nagy TL, Burkhardt JK, Turlier H, Weiner OD, bioRxiv 2025 May
    Cell protrusions and contractions generate long-range membrane tension propagation.
    De Belly H, Yan S, Borja da Rocha H, Ichbiah S, Town JP, Zager PJ, Estrada DC, Meyer K, Turlier H, Bustamante C, Weiner OD, Cell 2023 Jul 186 14 3049-3061.e15
    Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate.
    De Belly H, Stubb A, Yanagida A, Labouesse C, Jones PH, Paluch EK, Chalut KJ, Cell Stem Cell 2021 Feb 28 2 273-284.e6
  • Honors & Awards
    • European Molecular Biology Organization Postdoctoral Fellowship
    • Marie Sklodowska-Curie PhD Fellowship
    • NIH Pathway to Independence Award (K99/R00)