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Alexander Tatara, M.D.,  Ph.D.

Alexander Tatara, M.D., Ph.D.

Titles and Appointments

Assistant Professor

School
Medical School
Department
Internal Medicine | Biomedical Engineering
Graduate Programs
Biomedical Engineering, Molecular Microbiology

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Alexander Tatara, M.D., PhD., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern and a member of its Division of Infectious Diseases and Geographic Medicine. He also has a secondary appointment in the Department of Biomedical Engineering. His clinical interests include preventing and treating musculoskeletal infections.

    Originally from Illinois, Dr. Tatara holds a bachelor’s degree in biomedical engineering from Washington University in St. Louis. He received his Ph.D. in bioengineering at Rice University in Houston and his medical degree from Baylor College of Medicine in Houston. He completed internal medicine residency training at Massachusetts General Hospital and infectious diseases fellowship training at Massachusetts General Hospital and Brigham and Women’s Hospital in Boston. He completed his post-doctoral fellowship training at the Harvard University Wyss Institute for Biologically Inspired Engineering and the Harvard School of Engineering and Applied Sciences.

    Certified by the American Board of Internal Medicine in Internal Medicine and Infectious Diseases, he joined the UT Southwestern Faculty in 2024.

    Dr. Tatara’s research interests include the design of new biomaterials, tissue engineering strategies, mechanisms of pathogen virulence, and immunoengineering to prevent and treat infection. To date, his work has resulted in 41 peer-reviewed publications, five book chapters, and one patent. He is also the author of the clinical textbook "The Infectious Diseases Consult Handbook," published by Springer Nature (2023).

    He has been recognized with numerous national and international awards, including the Young Investigator Award from the Wake Forest Institute for Regenerative Medicine (2016), Milton Huppert Graduate Student Award from the Medical Mycological Society of the Americas (2016), Outstanding Research Award by the Society for Biomaterials (2019), and the Maxwell Finland Research Award from the Massachusetts Infectious Diseases Society (2022). He is an NIH NIAID K08 reciepient (2024-2029).

  • Education
    Undergraduate School
    Washington University in St. Louis School of Medicine (2010), Biomedical Engineering
    Graduate School
    Rice University (2017)
    Medical School
    Baylor College of Medicine (2018)
    Residency
    Massachusetts General Hospital (2020), Internal Medicine
    Fellowship
    Massachusetts General Hospital (2024), Infectious Diseases
  • Research Interest
    • Bacterial pathogenesis
    • Biomaterials science
    • Device Infection
    • Host immunity
    • Orthopedic immunology
    • Tissue engineering
  • Publications

    Star Featured Publications

    Fishy story: paradoxical reaction associated with Mycobacterium marinum.
    Tatara AM, Basgoz N, Nelson SB, BMJ Case Rep 2024 Aug 17 8
    Preventability of Hospital Deaths in Patients with Non-Ventilator Hospital-Acquired Pneumonia.
    Tatara AM, Apostolopoulou A, Agan AA, DelloStritto L, Rhee C, Klompas M, Clin Infect Dis 2024 Aug
    Rates and Outcomes of Periprosthetic Joint Infection in Persons Who Inject Drugs.
    Humphrey TJ, Tatara AM, Bedair HS, Alpaugh K, Melnic CM, Nelson SB, J Arthroplasty 2023 Jan 38 1 152-157
    Repair of complex ovine segmental mandibulectomy utilizing customized tissue engineered bony flaps.
    Watson E, Pearce HA, Hogan KJ, van Dijk NWM, Smoak MM, Barrios S, Smith BT, Tatara AM, Woernley TC, Shum J, Pearl CB, Melville JC, Ho T, Hanna IA, Demian N, van den Beucken JJJP, Jansen JA, Wong ME, Mikos AG, PLoS One 2023 18 2 e0280481
    Antiplatelet therapy for Staphylococcus aureus bacteremia: Will it stick?
    Tatara AM, Gandhi RG, Mooney DJ, Nelson SB, PLoS Pathog 2022 Feb 18 2 e1010240
    Antibiotic Prophylaxis for Total Joint Arthroplasty.
    Tatara AM, Nelson SB, Instr Course Lect 2022 71 107-116
    Protocol for fungal infection following the induction of epithelial cell loss in larval zebrafish.
    Wurster S, Ruiz OE, Tatara AM, Kontoyiannis DP, Eisenhoffer GT, STAR Protoc 2021 Dec 2 4 100963
    EGF-mediated suppression of cell extrusion during mucosal damage attenuates opportunistic fungal invasion.
    Wurster S, Ruiz OE, Samms KM, Tatara AM, Albert ND, Kahan PH, Nguyen AT, Mikos AG, Kontoyiannis DP, Eisenhoffer GT, Cell Rep 2021 Mar 34 12 108896
    Localized mandibular infection affects remote in vivo bioreactor bone generation.
    Watson E, Smith BT, Smoak MM, Tatara AM, Shah SR, Pearce HA, Hogan KJ, Shum J, Melville JC, Hanna IA, Demian N, Wenke JC, Bennett GN, van den Beucken JJJP, Jansen JA, Wong ME, Mikos AG, Biomaterials 2020 Oct 256 120185
    An Ovine Model of In Vivo Bioreactor-Based Bone Generation.
    Watson E, Tatara AM, van den Beucken JJJP, Jansen JA, Wong ME, Mikos AG, Tissue Eng Part C Methods 2020 Jul 26 7 384-396
  • Books

    Featured 

  • Honors & Awards
    • NIH NIAID Mentored Clinical Scientist Research Career Development Award (K08)
      (2024)
    • Harvard Medical School KL2/Catalyst Medical Research Investigator Training Awardee
      (2022-2024)
    • Maxwell Finland Research Award, the Massachusetts Infectious Diseases Society
      (2022)
    • Harvard University T32 (AI007061-41) Trainee
      (2021-2022)
    • Society for Biomaterials Outstanding Research by a Hospital Intern Award
      (2019)
    • The Musher Prize in Adult Infectious Diseases
      (2018)
    • Elected to the Alpha Omega Alpha Honor Medical Society
      (2017)
    • Richard R. Dickason Outstanding Physician Scientist Award
      (2017)
    • Medical Mycological Society of the Americas Milton Huppert Graduate Student Award
      (2016)
    • Wake Forest Institute for Regenerative Medicine Young Investigator Award
      (2016)
    • Kathy Crawford Service Award
      (2014)
    • Rice University Department of Biomedical Engineering Outstanding Teaching Assistant Award
      (2014)
    • Armed Forces Institute of Regenerative Medicine Fellow Travel Award
      (2013)
  • Professional Associations/Affiliations
    • Dallas County Medical Society (2024)
    • Infectious Diseases Society of America (2017)
    • Texas Medical Association (2024)