Alyssa Hasty, Ph.D. Vice Provost Sr Assoc Dean Faculty Affs and Career Dev Professor Endowed Title George A. and Nancy P. Shutt Professorship in Medical Science School Medical School Department Office of the Provost | Internal Medicine Graduate Programs Cell and Molecular Biology Biography In her leadership role as Vice Provost and Senior Associate Dean for Faculty Affairs and Career Development, Dr. Alyssa Hasty and her team assist departments with procedures related to faculty recruiting, hiring, and promotions. In addition, they work to elevate the faculty experience by identifying needs, researching approaches taken by others, implementing new programs, and evaluating results. Throughout her career, Dr. Hasty has focused on excellence as a scientist, mentor, and leader. She enjoys connecting people to resources that promote their professional development and creating new resources as the needs of faculty evolve. Dr. Hasty joined the UT Southwestern faculty in August of 2024, and in addition to her vice provost role is a Professor of Internal Medicine and a member of the Touchstone Diabetes Center. She received her doctoral degree from Vanderbilt University in pathology where she emerged as a leader in the field of immunometabolism, determining the role of the immune system in obesity-accelerated diseases. She completed a postdoctoral fellowship at Tokyo University. Her research has been continuously funded by agencies including the National Institutes of Health, the Veterans Affairs, and American Diabetes Association, the American heart Association, and the Mark Foundation for Cancer Research. She has published over 120 original papers. Education Undergraduate Tennessee Technological Univ (1994), Cell Biology Graduate School Vanderbilt University (1999), Pathology Publications Featured Publications Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease. Robertson KV, Rodriguez AS, Cartailler JP, Shrestha S, Schleh MW, Schroeder KR, Valenti AM, Kramer AT, Harrison FE, Hasty AH, J Neuroinflammation 2024 Sep 21 1 238 Adiposity, immunity, and inflammation: interrelationships in health and disease: a report from 24th Annual Harvard Nutrition Obesity Symposium, June 2023. Burak MF, Stanley TL, Lawson EA, Campbell SL, Lynch L, Hasty AH, Domingos AI, Dixit VD, Hotamisligil GS, Sheedy FJ, Dixon AE, Brinkley TE, Hill JA, Donath MY, Grinspoon SK, Am J Clin Nutr 2024 Jul 120 1 257-268 Knockdown of microglial iron import gene, DMT1, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer's disease. Robertson KV, Rodriguez AS, Cartailler JP, Shrestha S, Schroeder KR, Valenti AM, Harrison FE, Hasty AH, Res Sq 2024 Jun Deficiency of the hemoglobin-haptoglobin receptor, CD163, worsens insulin sensitivity in obese male mice. Schleh MW, Ameka M, Rodriguez A, Hasty AH, bioRxiv 2024 Jun Insulin at the intersection of thermoregulation and glucose homeostasis. Winn NC, Schleh MW, Garcia JN, Lantier L, McGuinness OP, Blair JA, Hasty AH, Wasserman DH, Mol Metab 2024 Mar 81 101901 Microglial-specific knockdown of iron import gene, Slc11a2, blunts LPS-induced neuroinflammatory responses in a sex-specific manner. Volk Robertson K, Schleh MW, Harrison FE, Hasty AH, Brain Behav Immun 2024 Feb 116 370-384 Obesity induces PD-1 on macrophages to suppress anti-tumour immunity Bader JE, Wolf MM, Lupica-Tondo GL, Madden MZ, Reinfeld BI, Arner EN, Hathaway ES, Steiner KK, Needle GA, Hatem Z, Landis MD, Faneuff EE, Blackman A, Wolf EM, Cottam MA, Ye X, Bates ME, Smart K, Wang W, Pinheiro LV, Christofides A, Smith D, Boussiotis VA, Haake SM, Beckermann KE, Wellen KE, Reinhart-King CA, Serezani CH, Lee CH, Aubrey C, Chen H, Rathmell WK, Hasty AH, Rathmell JC. 2024 Bovine Serum Albumin Elicits IL-33-Dependent Adipose Tissue Eosinophilia: Potential Relevance to Ovalbumin-induced Models of Allergic Disease. Caslin HL, Bolus WR, Thomas C, Toki S, Norlander AE, Peebles RS, Hasty AH, Immunohorizons 2023 Dec 7 12 842-852 Metaflammation in obesity and its therapeutic targeting. Schleh MW, Caslin HL, Garcia JN, Mashayekhi M, Srivastava G, Bradley AB, Hasty AH, Sci Transl Med 2023 Nov 15 723 eadf9382 Single cell RNA-sequencing suggests a novel lipid associated mast cell population following weight cycling. Caslin HL, Cottam MA, Betjemann AM, Mashayekhi M, Silver HJ, Hasty AH, bioRxiv 2023 Nov Results 1-10 of 132 1 2 3 4 5 Next Last Books Featured Books Apolipoprotein E and Reverse Cholesterol Transport: The Role of Recycling in Plasma and Intracellular Lipid Trafficking, pp.55-87.. In High Density Lipoproteins, Apolipoprotein E and Reverse Cholesterol Transport: The Role of Recycling in Plasma and Intracellular Lipid Trafficking, pp.55-87. LL Swift, AH Hasty, MF Linton, S Fazio (2007). Wiley-VCH Publishers Honors & Awards Kroc Lectureship at University of Chicago Endocrine GroupUniversity of Chicago (2024) Wendell-Griffith Lectureship in the Edward A. Doisy Department of Biochemistry and Molecular BiologySaint Louis University (student invited to recognize exceptional research and mentorship) (2024) Physiologist in Training Distinguished LectureUniversity of Mississippi (2023) VA Research Career ScientistVeteran Affairs (2021) Cornelius Vanderbilt Endowed ChairVanderbilt University (2017) AHA Established Investigator AwardAmerican Heart Association (2012) Featured in ADA Forefront magazineAmerican Diabetes Association (2010) MPB Department Graduate Education Service AwardVanderbilt University (2010) Abstract Selected for the Obesity Society's Annual Scientific MeetingPlenary Oral Abstract Presentation Session (only 7 of 1000 submitted abstracts chosen) (2008) NIH Workshop on the Establishment, Maintenance, and Turnover of Fat Depots travel awardNational Institutes of Health (2008) ADA Career Development AwardAmerican Diabetes Association (2007) Vanderbilt Digestive Diseases Research Center Young Investigator AwardVanderbilt University (2006) ADA Junior Faculty AwardAmerican Diabetes Association (2004) AHA Scientist Development GrantAmerican Heart Association (2003) Vanderbilt Clinical Nutrition Research Unit Young Investigator AwardVanderbilt University (2002) Professional Associations/Affiliations Fellow, American Heart Association (2008-2024) Member, American Association of Immunologists (2014-2024) Member, American Diabetes Association (2003-2024) Member, American Heart Association, Atherosclerosis Thrombosis and Vascular Biology Council (2002-2024) Member, American Physiological Society (2007-2024) Member, American Society for Nutrition (2016-2018) Member, Association of American Medical Colleges Group on Faculty Affairs (GFA) (2017-2024) Member, Digestive Diseases Research Center, VUMC (2006-2024) Member, International BioIron Society (2019-2024) Member, Society for Leukocyte Biology (2008-2011) Member, The Obesity Society (2008-2024) Member, Vanderbilt Center for Immunobiology (2018-2024) Member, Vanderbilt Diabetes Center, VUMC (2002-2024)
