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Justin Rousseau, M.D.

Justin Rousseau, M.D.

Deputy Chief Medical Informatics Officer for Neurosciences

Associate Professor

School
Medical School
Department
Neurology | Peter O'Donnell Jr. Brain Institute

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Joined UT Southwestern: 2023

    Justin Rousseau, MD, MMSc, is an Associate Professor in the Department of Neurology and the Peter O’Donnell Jr. Brain Institute at UT Southwestern. He is a member of the Clinical Informatics Center, serves as Deputy Chief Medical Informatics Officer for Neurosciences, and is a member of the Informatics Core of the UT Southwestern Clinical Translational Science Award (CTSA) Program. He is board-certified in neurology and clinical informatics. 

    Research: Dr. Rousseau seeks to advance brain health research and care through the secondary use of electronic health record (EHR) data. His research and development interests to achieve this include developing and applying biomedical informatics methods including natural language processing (NLP), information extraction, standard ontologies and terminologies, computable phenotyping, and data warehousing to identify, harvest, and make accessible pertinent biomedical and health care data to support evidence-based clinical decisions, information sharing through transitions of care, and health research.

    Dr. Rousseau leads clinical research informatics efforts to collect, manage, analyze, and warehouse health data to support the development of learning health systems and clinical research networks. Example projects include: (1) the Early Psychosis Intervention Network of Texas (EPINET-TX); (2) the Texas Childhood Trauma Research Network (TX-CTRN), and (3) the Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) study. During his time at Dell Medical School at UT Austin, Dr. Rousseau co-founded and co-directed the Data Core, which was adopted as part of Dell Medical School Enterprise Data Intelligence, a central resource for investigators accessing, managing, and analyzing clinical and non-clinical health-related data serving research and quality improvement activities through development of computable phenotypes to define patient cohorts, extraction of clinical data, and integration with other sources of data.

    Background: Built on foundational education in systems engineering, Dr. Rousseau obtained his medical degree from the University of Oklahoma Health Sciences Center. He completed his neurology residency at UC San Diego, where he was chief resident. He then completed an NIH National Library of Medicine fellowship and Master of Medical Sciences in Biomedical Informatics at Harvard Medical School and Brigham and Women’s Hospital with the Center for Evidence-based Imaging. He joined UT Southwestern after seven years with the Departments of Population Health and Neurology at Dell Medical School at UT Austin.

  • Education
    Medical School
    UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE (2010)
    Internship
    St. Mary Medical Center (2011), Internal Medicine
    Residency
    University of California San Diego (2014), Neurology
  • Research Interest
    • Biomedical Informatics
    • Clinical Informatics
    • Computable Phenotypes
    • Electronic Health Records
    • Natural Language Processing
    • Secondary Use of Electronic Health Records
  • Publications
    IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition
    Author Collaboration ID, Author Collaboration IS, Author Collaboration IC, Author Collaboration IC, Author Collaboration IN, Author Collaboration IS, Author Collaboration C&, Haslund-Gourley BS, Woloszczuk K, Hou J, Connors J, Cusimano G, Bell M, Taramangalam B, Fourati S, Mege N, Bernui M, Altman MC, Krammer F, van Bakel H, Maecker HT, Rouphael N, Diray-Arce J, Wigdah B, Kutzler MA, Cairns CB, Haddad EK, Comunale MA, Ozonoff A, Ehrlich LI, Melamed E, Sesma AF, Simon V, Pulendran B, Nadeau KC, Davis MM, McCoey GA, Sekaly R, Baden LR, Levy O, Schaenman J, Reed EF, Shaw AC, Hafler DA, Montgomery RR, Kleinstein SH, Becker PM, Augustine AD, Calfee CS, Erle DJ, Debakey ME, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Agudelo Higuita NI, Rousseau JF Nature communications 2024 Dec 15
    Hidden flaws behind expert-level accuracy of multimodal GPT-4 vision in medicine
    Jin Q, Chen F, Zhou Y, Xu Z, Cheung JM, Chen R, Summers RM, Rousseau JF, Ni P, Landsman MJ, Baxter SL, Al’Aref SJ, Li Y, Chen A, Brejt JA, Chiang MF, Peng Y, Lu Z npj Digital Medicine 2024 Dec 7
    Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
    Author Collaboration IN, Author Collaboration IS, Author Collaboration C&, Author Collaboration ID, Author Collaboration IS, Author Collaboration IC, Author Collaboration IC, Ozonoff A, Jayavelu ND, Liu S, Melamed E, Milliren CE, Qi J, Geng LN, McComsey GA, Cairns CB, Baden LR, Schaenman J, Shaw AC, Samaha H, Seyfert-Margolis V, Krammer F, Rosen LB, Steen H, Syphurs C, Dandekar R, Shannon CP, Sekaly RP, Ehrlich LI, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Agudelo Higuita NI, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Sesma AF, Simon V, van Bakel H, Kim-Schulze S, Hafler DA, Levy O, Kraft M, Bime C, Haddad EK, Calfee CS, Erle DJ, Langelier CR, Eckalbar W, Bosinger SE, Peters B, Kleinstein SH, Rousseau JF Nature communications 2024 Dec 15
    Beyond bias: Aggregate approaches to conflicts of interest research and policy in biomedical research
    Graham SS, Harrison KR, Edward JC, Majdik ZP, Barbour JB, Rousseau JF World Medical and Health Policy 2024 Sep 16 489-505
    Patient Characteristics, Management, and Outcomes in a Novel Cohort of Primary Hyperparathyroidism
    Sant VR, Elnakieb Y, Lehmann C, Rousseau JF, Maalouf NM Journal of the Endocrine Society 2024 Aug 8
    Comparing diagnostic criteria for posttraumatic stress disorder in a diverse sample of trauma-exposed youth
    Dodd CG, Kirk CL, Rathouz PJ, Custer J, Garrett AS, Taylor L, Rousseau JF, Claasen C, Morgan MM, Newport DJ, Wagner KD, Nemeroff CB Journal of Traumatic Stress 2024 Aug 37 606-616
    The role of resilience in the development of depression, anxiety, and post-traumatic stress disorder after trauma in children and adolescents
    Srivastava AV, Brown R, Newport DJ, Rousseau JF, Wagner KD, Guzick A, Devargas C, Claassen C, Ugalde IT, Garrett A, Gushanas K, Liberzon I, Cisler JM, Nemeroff CB Psychiatry research 2024 Apr 334
    Comparative effectiveness of dexamethasone in treatment of hospitalized COVID-19 patients in the United States during the first year of the pandemic: Findings from the National COVID Cohort Collaborative (N3C) data repository
    Zhou R, Johnson KE, Rousseau JF, Rathouz PJ, Wilcox AB, Lee AM, Graves A, Anzalone A, Manna A, Saha A, Olex A, Zhou A, Williams AE, Southerland A, Girvin AT, Walden A, Sharathkumar AA, Amor B, Bates B, Hendricks B, Patel B, Alexander C, Bramante C, Ward-Caviness C, Madlock-Brown C, Suver C, Chute C, Dillon C, Wu C, Schmitt C, Takemoto C, Housman D, Gabriel D, Eichmann DA, Mazzotti D, Brown D, Boudreau E, Hill E, Zampino E, Carlson Marti E, Pfaff ER, French E, Koraishy FM, Mariona F, Prior F, Sokos G, Martin G, Lehmann H, Spratt H, Mehta H, Liu H, Sidky H, Hayanga JW, Pincavitch J, Clark J, Harper JR, Islam J, Ge J, Gagnier J, Saltz JH, Saltz J, Loomba J, Buse J, Mathew J, Rutter JL, McMurry JA, Guinney J, Starren J, Crowley K, Bradwell KR, Walters KM, Wilkins K, Gersing KR, Cato KD, Murray K, Kostka K, Northington L, Pyles LA, Misquitta L, Cottrell L, Portilla L, Deacy M, Bissell MM, Clark M, Emmett M, Saltz MM, Palchuk MB, Haendel MA, Adams M, Temple-O'Connor M, Kurilla MG, Morris M, Qureshi N, Safdar N, Garbarini N, Sharafeldin N, Sadan O, Francis PA, Burgoon PW, Robinson P, Payne PR, Fuentes R, Jawa R, Erwin-Cohen R, Patel R, Moffitt RA, Zhu RL, Kamaleswaran R, Hurley R, Miller RT, Pyarajan S, Michael SG, Bozzette S, Mallipattu S, Vedula S, Chapman S, O'Neil ST, Setoguchi S, Hong SS, Johnson S, Bennett TD, Callahan T, Topaloglu U, Sheikh U, Gordon V, Subbian V, Kibbe WA, Hernandez W, Beasley W, Cooper W, Hillegass W, Tanner Zhang X PloS one 2024 Mar 19
    The risk and burden of thromboembolic and hemorrhagic events in patients with malignant gliomas receiving bevacizumab
    Dasgupta P, Ou A, Lin H, Gregory T, Alfaro-Munoz KD, Yuan Y, Afshar-Khargan V, Kamiya-Matsuoka C, Rousseau JF, Majd NK Journal of Neuro-Oncology 2024 Mar 167 181-188
    Clinical and molecular determinants of bleeding-related adverse outcomes in high-grade glioma
    Dasgupta P, Rousseau JF Journal of Neuro-Oncology 2024 Feb 166 569-574