Justin Rousseau, M.D. Titles and Appointments Deputy Chief Medical Informatics Officer for Neurosciences Associate Professor School Medical School Department Neurology | Peter O'Donnell Jr. Brain Institute You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Joined UT Southwestern: 2023 Justin Rousseau, MD, MMSc, is an Associate Professor in the Department of Neurology and the Peter O’Donnell Jr. Brain Institute at UT Southwestern. He is a member of the Clinical Informatics Center, serves as Deputy Chief Medical Informatics Officer for Neurosciences, and is a member of the Informatics Core of the UT Southwestern Clinical Translational Science Award (CTSA) Program. He is board-certified in neurology and clinical informatics. Research: Dr. Rousseau seeks to advance brain health research and care through the secondary use of electronic health record (EHR) data. His research and development interests to achieve this include developing and applying biomedical informatics methods including natural language processing (NLP), information extraction, standard ontologies and terminologies, computable phenotyping, and data warehousing to identify, harvest, and make accessible pertinent biomedical and health care data to support evidence-based clinical decisions, information sharing through transitions of care, and health research. Dr. Rousseau leads clinical research informatics efforts to collect, manage, analyze, and warehouse health data to support the development of learning health systems and clinical research networks. Example projects include: (1) the Early Psychosis Intervention Network of Texas (EPINET-TX); (2) the Texas Childhood Trauma Research Network (TX-CTRN), and (3) the Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) study. During his time at Dell Medical School at UT Austin, Dr. Rousseau co-founded and co-directed the Data Core, which was adopted as part of Dell Medical School Enterprise Data Intelligence, a central resource for investigators accessing, managing, and analyzing clinical and non-clinical health-related data serving research and quality improvement activities through development of computable phenotypes to define patient cohorts, extraction of clinical data, and integration with other sources of data. Background: Built on foundational education in systems engineering, Dr. Rousseau obtained his medical degree from the University of Oklahoma Health Sciences Center. He completed his neurology residency at UC San Diego, where he was chief resident. He then completed an NIH National Library of Medicine fellowship and Master of Medical Sciences in Biomedical Informatics at Harvard Medical School and Brigham and Women’s Hospital with the Center for Evidence-based Imaging. He joined UT Southwestern after seven years with the Departments of Population Health and Neurology at Dell Medical School at UT Austin. Education Medical School UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE (2010) Internship St. Mary Medical Center (2011), Internal Medicine Residency University of California San Diego (2014), Neurology Other Post Graduate Training Harvard Medical School (2016) Research Interest Biomedical Informatics Clinical Informatics Computable Phenotypes Electronic Health Records Natural Language Processing Secondary Use of Electronic Health Records Publications Validity of the PHQ-9A as a self-report screener for major depressive disorder in youth ages 10–12 years Stewart SM, Sanei S, Abu-Samaha A, Emslie GJ, Rathouz PJ, Belford A, Garrett A, Shotwell J, Taylor LK, Rousseau JF, Shahidullah JD, Newport J, Wagner KD, Nemeroff CB Journal of affective disorders 2026 Jan 392 Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients Author Collaboration IN, Pickering H, Schaenman J, Phan HV, Maguire C, Tsitsiklis A, Rouphael N, Higuita NI, Atkinson MA, Brakenridge S, Fung M, Messer W, Seyfert-Margolis V, Rahman A, Wong K, Michelotti G, Hutton SR, Overton JA, Nagle C, Sheidy J, Schearer P, Ulring K, Mege N, Rogowski B, Tegos GP, McLin R, Furukawa S, Bell MR, Semenza NC, Croen B, Martens M, Smith CM, Simmons B, Goonewardene IM, Kim JN, Powell DL, Melnyk N, Lin E, Lee E, Edwards C, Joyner D, Woloszczuk K, Connors J, Cusimano G, Bernui M, Kutzler MA, Haddad EK, Cairns CB, Ribeiro SP, Tribout H, Rousseau JF Nature communications 2025 Dec 16 Dissecting clinical features of COVID-19 in a cohort of 21,312 acute care patients Maguire C, Soloveichik E, Blinchevsky N, Miller J, Morrison R, Busch J, Michael Brode W, Wylie D, Rousseau J, Melamed E Communications Medicine 2025 Dec 5 SARS-CoV-2 humoral immune responses in convalescent individuals over 12 months reveal severity-dependent antibody dynamics Siles Alvarado N, Schuler M, Maguire C, Amengor DA, Nguyen AW, Wilen RE, Rogers J, Bazzi S, Caslin B, DiPasquale C, Abigania M, Olson E, Creaturo J, Hurley K, Triplett TA, Rousseau JF, Strakowski SM, Wylie D, Maynard JA, Ehrlich LI, Melamed E Communications Medicine 2025 Dec 5 Leveraging long context in retrieval augmented language models for medical question answering Zhang G, Xu Z, Jin Q, Chen F, Fang Y, Liu Y, Rousseau JF, Xu Z, Lu Z, Weng C, Peng Y npj Digital Medicine 2025 Dec 8 Type 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort Author Collaboration IN, Jayavelu ND, Qi J, Milliren CE, Ozonoff A, Liu S, Levy O, Baden LR, Melamed E, McComsey GA, Cairns CB, Schaenman J, Shaw AC, Hafler DA, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Agudelo Higuita NI, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Geng LN, Sesma AF, Simon V, Krammer F, Bime C, Calfee CS, Bosinger SE, Eckalbar W, Steen H, Maecker HT, Becker PM, Augustine AD, Holland SM, Rosen LB, Lee S, Vaysman T, Ozonoff A, Diray-Arce J, Chen J, Kho A, Milliren CE, Hoch A, Chang AC, McEnaney K, Barton B, Rousseau JF Journal of Allergy and Clinical Immunology: Global 2025 Nov 4 The structure of posttraumatic stress symptoms in youth with and without obsessive-compulsive disorder: New insights using factor and network analysis Pinciotti CM, Cervin M, Drummond KN, Shahidullah JD, Rousseau JF, Dodd CG, Ramirez M, Hettema JM, Richmond R, Taylor LK, Monnat L, Proch L, Teng F, Goodman WK, Storch EA, Guzick AG, Newport DJ, Wagner KD, Nemeroff CB Journal of Mood and Anxiety Disorders 2025 Sep 11 Development and validation of natural language processing algorithms in the national ENACT network Wang Y, Hilsman J, Li C, Morris M, Heider PM, Fu S, Kwak MJ, Wen A, Applegate JR, Wang L, Bernstam E, Liu H, Chang J, Harris DR, Corbeau A, Henderson D, Osborne J, Kennedy RE, Garduno-Rapp NE, Rousseau JF, Yan C, Chen Y, Patel MB, Murphy TJ, Malin BA, Park CM, Fan JW, Sohn S, Pagali S, Peng Y, Pathak A, Wu Y, Xia Z, Loguercio S, Reis SE, Visweswaran S Journal of Clinical and Translational Science 2025 Aug 9 Clinical characteristics and longitudinal associations with obsessive-compulsive disorder in youth exposed to trauma Pinciotti CM, Rathouz PJ, Guzick AG, Shahidullah JD, Bivins EJ, Riddle DB, Onyeka O“, Storch EA, Goodman WK, Franco K, Rousseau JF, Newport DJ, Wagner KD, Nemeroff CB Journal of Mood and Anxiety Disorders 2025 Jun 10 Longitudinal Effects of Negative Ethnic-Racial Identity Affect on Internalizing Symptoms in Youth of Latiné Background Exposed to Interpersonal Trauma Stewart SM, Aksan N, Bancroft A, Shahidullah JD, Krantz SM, Guerra M, Sandoval J, Garza C, Viana AG, Morgan M, DeVargas C, Rousseau JF, Newport DJ, Wagner KD, Nemeroff CB The Journal of clinical psychiatry 2025 Mar 86 Results 1-10 of 66 1 2 3 4 5 Next Last