Janko Gospocic, Ph.D. Titles and Appointments Assistant Professor Endowed Title Southwestern Medical Foundation Scholar in Biomedical Research School Graduate School Department Psychiatry | Cecil H. and Ida Green Center for Reproductive Biology Sciences Graduate Programs Genetics, Development and Disease, Neuroscience Biography Dr. Janko Gospocic graduated with a M.S. in Molecular Biology from the University of Zagreb. He then received his Ph.D. in Developmental Biology and Genetics at the European Molecular Biology Laboratory (EMBL), where he studied the role of the imprinted genes in cardiac development. Dr. Gospocic then conducted his postdoctoral training at the University of Pennsylvania’s Epigenetics Institute. His postdoctoral work involved dissecting the molecular mechanisms behind the social transitions in Harpegnathos saltator ants. He joined the Department of Psychiatry in 2023 as an Endowed Scholar. Research Interest Epigenetics, chromatin biology, gene regulation, social behavior, aging, neurodegeneration Publications Featured Publications Hormonal gatekeeping via the blood-brain barrier governs caste-specific behavior in ants. Ju L, Glastad KM, Sheng L, Gospocic J, Kingwell CJ, Davidson SM, Kocher SD, Bonasio R, Berger SL, Cell 2023 Sep 186 20 4289-4309.e23 Long ant life span is maintained by a unique heat shock factor. Glastad KM, Roessler J, Gospocic J, Bonasio R, Berger SL, Genes Dev 2023 May 37 9-10 398-417 Ensheathing glia promote increased lifespan and healthy brain aging. Sheng L, Shields EJ, Gospocic J, Sorida M, Ju L, Byrns CN, Carranza F, Berger SL, Bonini N, Bonasio R, Aging Cell 2023 May 22 5 e13803 Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones. Gospocic J, Glastad KM, Sheng L, Shields EJ, Berger SL, Bonasio R, Cell 2021 Nov 184 23 5807-5823.e14 Correct dosage of X chromosome transcription is controlled by a nuclear pore component. Aleman JR, Kuhn TM, Pascual-Garcia P, Gospocic J, Lan Y, Bonasio R, Little SC, Capelson M, Cell Rep 2021 Jun 35 11 109236 Social reprogramming in ants induces longevity-associated glia remodeling. Sheng L, Shields EJ, Gospocic J, Glastad KM, Ratchasanmuang P, Berger SL, Raj A, Little S, Bonasio R, Sci Adv 2020 Aug 6 34 eaba9869 Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH. Torre E, Dueck H, Shaffer S, Gospocic J, Gupte R, Bonasio R, Kim J, Murray J, Raj A, Cell Syst 2018 Feb 6 2 171-179.e5 The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants. Gospocic J, Shields EJ, Glastad KM, Lin Y, Penick CA, Yan H, Mikheyev AS, Linksvayer TA, Garcia BA, Berger SL, Liebig J, Reinberg D, Bonasio R, Cell 2017 Aug 170 4 748-759.e12 An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. Pinto AR, Paolicelli R, Salimova E, Gospocic J, Slonimsky E, Bilbao-Cortes D, Godwin JW, Rosenthal NA, PLoS One 2012 7 5 e36814 Results 1-9 of 9 1
