Robert Collins, M.D. Professor Endowed Title H. Lloyd and Willye V. Skaggs Professorship in Medical Research; Sydney and J.L. Huffines Distinguished Chair in Cancer Research in Honor of Eugene Frenkel, M.D. School Medical School Department Internal Medicine You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Robert H. Collins Jr., M.D., FACP, is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of the Division of Hematology and Oncology. He serves as Director of the Hematologic Malignancies and Cellular Therapy Program and the Combined Adult/Pediatric Stem Cell Transplant Program. He holds the Sydney and J.L. Huffines Distinguished Chair in Cancer Research in Honor of Eugene Frenkel, M.D., and holds the H. Lloyd and Willye V. Skaggs Professorship in Medical Research. Originally from St. Louis, Dr. Collins earned his bachelor's degree and his medical degree from the University of Missouri-Kansas City School of Medicine. He completed his internal medicine residency at Baylor University Medical Center in Dallas. He received advanced training through a fellowship in hematology and oncology at the University of California-Los Angeles. Certified by the American Board of Internal Medicine in medical oncology, Dr. Collins has 35 years of experience in bone marrow transplantation and has participated in 3,000 autologous and allogeneic transplants. A recognized leader in the field of adoptive immunotherapy and molecular-targeted therapy, Dr. Collins specializes in hematologic malignancies, including leukemia, lymphoma, and myelodysplastic syndrome. Dr. Collins is a Fellow of the American College of Physicians and a member of numerous scientific and medical organizations, including the American Association for the Advancement of Science, the American Society of Hematology, the American Society of Clinical Oncology, and the American Society for Transplantation and Cellular Therapy. Dr. Collins has led studies of donor leukocyte infusions through an international network of more than 100 centers and has participated in several dozen clinical trials, phases one through three, investigating novel approaches to hematologic malignancies and blood and marrow transplantation. He has been published more than 150 times in leading journals, including The Lancet, JAMA, The New England Journal of Medicine, Blood, and the Journal of Clinical Oncology. Dr. Collins is an active clinician, focusing on hematologic malignancies. He also instructs medical students, residents, and fellows in these disciplines at UT Southwestern Medical School. Dr. Collins is a recipient of the John J. Kenny Award from the Leukemia & Lymphoma Society, the Lee Grubman Hero of the Year Award from the Lymphoma Research Foundation, and the Patricia and William L. Watson Jr., M.D. Award, UT Southwestern’s highest honor in clinical medicine. Personal Note During his free time, Dr. Collins enjoys reading, listening to music, and spending time with his family. He also enjoys outdoor activities. Education Medical School University of Missouri-Kansas City School of Medicine (1984) Residency Baylor University Medical Center (1987), Internal Medicine Fellowship UCLA (1989), Hematology Oncology Research Interest Adoptive immunotherapy Immunology of allogeneic hematopoietic cell transplantations Non-myeloablative stem cell transplantation Publications Featured Publications Crenolanib and Intensive Chemotherapy in Adults With Newly Diagnosed FLT3-Mutated AML. Wang ES, Goldberg AD, Tallman M, Walter RB, Karanes C, Sandhu K, Vigil CE, Collins R, Jain V, Stone RM, J Clin Oncol 2024 Feb JCO2301061 Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial. Burd A, Levine RL, Ruppert AS, Mims AS, Borate U, Stein EM, Patel P, Baer MR, Stock W, Deininger M, Blum W, Schiller G, Olin R, Litzow M, Foran J, Lin TL, Ball B, Boyiadzis M, Traer E, Odenike O, Arellano M, Walker A, Duong VH, Kovacsovics T, Collins R, Shoben AB, Heerema NA, Foster MC, Vergilio JA, Brennan T, Vietz C, Severson E, Miller M, Rosenberg L, Marcus S, Yocum A, Chen T, Stefanos M, Druker B, Byrd JC, Nat Med 2020 Dec 26 12 1852-1858 Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML. DiNardo CD, Stein EM, de Botton S, Roboz GJ, Altman JK, Mims AS, Swords R, Collins RH, Mannis GN, Pollyea DA, Donnellan W, Fathi AT, Pigneux A, Erba HP, Prince GT, Stein AS, Uy GL, Foran JM, Traer E, Stuart RK, Arellano ML, Slack JL, Sekeres MA, Willekens C, Choe S, Wang H, Zhang V, Yen KE, Kapsalis SM, Yang H, Dai D, Fan B, Goldwasser M, Liu H, Agresta S, Wu B, Attar EC, Tallman MS, Stone RM, Kantarjian HM N. Engl. J. Med. 2018 06 378 25 2386-2398 Identification and monitoring of graft-versus-host specific T-cell clone in stem cell transplantation. Michálek J, Collins RH, Hill BJ, Brenchley JM, Douek DC Lancet 2003 Apr 361 9364 1183-5 Definitive separation of graft-versus-leukemia- and graft-versus-host-specific CD4+ T cells by virtue of their receptor beta loci sequences. Michalek J, Collins RH, Durrani HP, Vaclavkova P, Ruff LE, Douek DC, Vitetta ES Proc. Natl. Acad. Sci. U.S.A. 2003 Feb 100 3 1180-4 Prospective trial of chemotherapy and donor leukocyte infusions for relapse of advanced myeloid malignancies after allogeneic stem-cell transplantation. Levine JE, Braun T, Penza SL, Beatty P, Cornetta K, Martino R, Drobyski WR, Barrett AJ, Porter DL, Giralt S, Leis J, Holmes HE, Johnson M, Horowitz M, Collins RH J. Clin. Oncol. 2002 Jan 20 2 405-12 Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution. Douek DC, Vescio RA, Betts MR, Brenchley JM, Hill BJ, Zhang L, Berenson JR, Collins RH, Koup RA Lancet 2000 May 355 9218 1875-81 Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation. Collins RH, Shpilberg O, Drobyski WR, Porter DL, Giralt S, Champlin R, Goodman SA, Wolff SN, Hu W, Verfaillie C, List A, Dalton W, Ognoskie N, Chetrit A, Antin JH, Nemunaitis J J. Clin. Oncol. 1997 Feb 15 2 433-44 Brief report: donor-derived long-term multilineage hematopoiesis in a liver-transplant recipient. Collins RH, Anastasi J, Terstappen LW, Nikaein A, Feng J, Fay JW, Klintmalm G, Stone MJ N. Engl. J. Med. 1993 Mar 328 11 762-5 Results 1-9 of 9 1 Honors & Awards Best Doctors Hall of FameD Magazine (2022) Top Doctor of 2022Castle Connolly (2022) Top DoctorsU.S. News & World Report (2013-2016) Top Doctors North TexasCastle Connolly (2011-2022) Dr. John J. Kenny AwardLeukemia & Lymphoma Society (2009) Super DoctorsTexas Monthly (2008-2022) The Best Doctors in AmericaBest Doctor (1998-2022) Best Doctors in DallasD Magazine (1994-2022) Basic Science AwardSt. Louis Friends of the UMKC School of Medicine (0) Curators' Scholarship for Academic ExcellenceUniversity of Missouri (0) Deans List for All Undergraduate SemestersUniversity of Missouri-Kansas City (0) FellowAmerican College of Physicians (0) Flarscheim Scholarship for Academic ExcellenceUniversity of Missouri-Kansas City (0) Outstanding Achievement in the College of Arts and SciencesUniversity of Missouri-Kansas City (0) The Best Doctors in America (0) Professional Associations/Affiliations American Association for the Advancement of Science American College of Physicians American Society for Blood and Marrow Transplantation American Society of Clinical Oncology American Society of Hematology Dallas County Medical Society International Society for Experimental Hematology Leukemia Association of North America Leukemia Society of America Texas Society of Medical Oncology
