Vanessa Nomellini, M.D., Ph.D.

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Vanessa Nomellini, MD, PhD is an Associate Professor in the Division of Burn, Trauma, Acute and Critical Care Surgery at UT Southwestern. Dr. Nomellini earned her MD from Loyola University, where she also earned a PhD in Cellular and Molecular Biochemistry. She completed her general surgery residency at the University of Wisconsin and her fellowship in Surgical Critical Care at the University of Pennsylvania. She joined the faculty at the University of Cincinnati in 2016, where she developed her research program focused on immune suppression in critically ill trauma and septic patients. She also developed an ICU Recovery Program, where the most complex ICU survivors are followed and managed long term. She was recently recruited to UT Southwestern in September to be the director of research for the division and as part of the leadership for CORT along with Drs. Levi and Carlson. She currently has an R35 from NIGMS focused on both animal studies of immune suppression, as well as a prospective observational human study characterizing the immune suppression in these patients.

Medical School

Loyola University Chicago Stritch School of Medicine (2010)

Residency

University of Wisconsin Hospital and Clinics (2015), General Surgery

Fellowship

University of Pennsylvania Health System (2016), Surgical Critical Care

• critical care
• emergency general surgery
• immune dysfunction in injury and infection
• post-ICU syndrome
• sepsis
• trauma

Featured Publications

Evaluating the Utility of High Sensitivity Troponin in Blunt Cardiac Injury.

Nathwani JN, Baucom MR, Salvator A, Makley AT, Tsuei BJ, Droege CA, Goodman MD, Nomellini V, J Surg Res 2022 Sep 281 104-111

Tracheostomy decreases continuous analgesia and sedation requirements.

Wallen TE, Elson NC, Singer KE, Hayes HV, Salvator A, Droege CA, Nomellini V, Pritts TA, Goodman MD, J Trauma Acute Care Surg 2022 May

Acute and Chronic Hematologic Implications of Emergency and Elective Splenectomy.

Singer KE, Bercz AP, Morris MC, Elson NC, Wallen TE, Hanseman D, Pritts TA, Nomellini V, Patel SH, Makley AT, Goodman MD, J Surg Res 2021 11 267 197-202

Hitting the Vasopressor Ceiling: Finding Norepinephrine Associated Mortality in the Critically Ill.

Singer KE, Sussman JE, Kodali RA, Winer LK, Heh V, Hanseman D, Nomellini V, Pritts TA, Droege CA, Goodman MD, J Surg Res 2021 09 265 139-146

Burn Injury Impairs Neutrophil Chemotaxis Through Increased Ceramide.

Beckmann N, Schumacher F, Kleuser B, Gulbins E, Nomellini V, Caldwell CC, Shock 2021 07 56 1 125-132

Lymphocyte Immunosuppression and Dysfunction Contributing to Persistent Inflammation, Immunosuppression, and Catabolism Syndrome (PICS).

Bergmann CB, Beckmann N, Salyer CE, Crisologo PA, Nomellini V, Caldwell CC, Shock 2021 06 55 6 723-741

Olfactomedin 4-Positive Neutrophils Are Upregulated after Hemorrhagic Shock.

Kassam AF, Levinsky NC, Mallela JP, Angel K, Opoka A, Lahni P, Sahay RD, Fei L, Nomellini V, Wong HR, Alder MN, Am J Respir Cell Mol Biol 2021 02 64 2 216-223

Staging and Personalized Intervention for Infection and Sepsis.

Beckmann N, Salyer CE, Crisologo PA, Nomellini V, Caldwell CC, Surg Infect (Larchmt) 2020 Nov 21 9 732-744

Immunotherapeutic options for inflammation in trauma.

Tobin JM, Gavitt BJ, Nomellini V, Dobson GP, Letson HL, Shackelford SA, J Trauma Acute Care Surg 2020 08 89 2S Suppl 2 S77-S82

Distinct Neutrophil Populations in the Spleen During PICS.

Sengupta S, Caldwell CC, Nomellini V, Front Immunol 2020 11 804

 Featured Books

Aging and Impairment of Innate Immunity. In Contributions to Microbiology: Trends in Innate Immunity

Nomellini V, Gomez C, and Kovacs EJ (2008). Basel, Switzerland, Karger AG

Sex hormones and immunosenescence. In Ageing, Immunity and Inflammation

Gomez CR, Nomellini V, and Kovacs EJ (2009). New York, NY, Springer Press

Modern Techniques for Protein Assessment. In Success in Academic Surgery: Basic Science

Nomellini V, Kennedy GD (2013). New York, NY, Springer Press

Conscious Sedation. In Mont Reid Handbook for General Surgery Residents

Johnson BL, Nomellini V (2016). Philadelphia, PA, Elsevier

Physiologic Response to Trauma. In The Trauma Manuel: Trauma and Acute Care Surgery

Nomellini V, Sims C. 2019 (2019). Philadelphia, PA, Wolters Kluwer

• Nominee for Cincinnati Business Courier’s Forty under 40 Award
  (2021)
• Faculty induction into Alpha Omega Alpha
  (2020)
• Nominee for Cincinnati Business Courier’s Forty under 40 Award
  (2019)
• Fellow of the American College of Surgeons
  (2018)
• Nominee for the Searle Scholars Program
  (2017)
• Hospital of the University of Pennsylvania Rhoads 5 Fellow of the Year
  (2016)
• Penn Presbyterian Trauma Surgical ICU Fellow of the Year
  (2016)
• Emergency Medicine Trauma Award
  (2014)
• Highest Junior Exam Score, American Board of Surgery In-Service Training Exam
  (2011)

• American College of Surgeons (2016)
• Association for Academic Surgery (2016)
• Eastern Association for the Surgery of Trauma (2016)
• Shock Society (2016)
• Society for University Surgeons (2021)
• Society of Critical Care Medicine (2015)
• Surgical Biology Club (2021)