Education

Undergraduate
University of Indianapolis (2002)
Graduate School
Indiana Univ Purdue Univ Sch M (2007)

Research Interest

  • Chromatin and transcription regulation
  • Friedreich's ataxia
  • Modeling neurodegenerative diseases using induced pluripotent stem cells (iPSCs)
  • Post-translational regulatory mechanisms
  • Trinucleotide repeat expansions

Publications

Featured Publications LegendFeatured Publications

Selected Histone Deacetylase Inhibitors Reverse the Frataxin Transcriptional Defect in a Novel Friedreich's Ataxia Induced Pluripotent Stem Cell-Derived Neuronal Reporter System.
Schreiber AM, Li Y, Chen YH, Napierala JS, Napierala M, Front Neurosci 2022 16 836476
Reverse Phase Protein Array Reveals Correlation of Retinoic Acid Metabolism With Cardiomyopathy in Friedreich's Ataxia.
Napierala JS, Rajapakshe K, Clark A, Chen YY, Huang S, Mesaros C, Xu P, Blair IA, Hauser LA, Farmer J, Lynch DR, Edwards DP, Coarfa C, Napierala M, Mol Cell Proteomics 2021 20 100094
A CRISPR-Cas9, Cre-lox, and Flp-FRT Cascade Strategy for the Precise and Efficient Integration of Exogenous DNA into Cellular Genomes.
Li J, Li Y, Pawlik KM, Napierala JS, Napierala M, CRISPR J 2020 12 3 6 470-486
Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy.
Li J, Li Y, Wang J, Gonzalez TJ, Asokan A, Napierala JS, Napierala M, Hum Gene Ther 2020 08 31 15-16 839-851

Honors & Awards

  • Aspen Cancer Conference Fellow (2012)
  • Research Training Fellowship in Ataxia (2017)
    American Academy of Neurology, National Ataxia Foundation and American Brain Foundation
  • Young Investigator Award (2017)
    National Ataxia Foundation

Professional Associations/Affiliations

  • American Academy of Neurology (2016)