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Sukh Makhnoon, Ph.D.

Sukh Makhnoon, Ph.D.

Assistant Professor

School
School of Public Health
Department
Public Health | Harold C. Simmons Comprehensive Cancer Center
  • Biography

    Dr. Sukh Makhnoon, PhD, MS, is an Assistant Professor in the O’Donnell School of Public Health at UT Southwestern Medical Center, with a secondary appointment at the Simmons Comprehensive Cancer Center. Dr. Makhnoon is a public health geneticist who focuses on implementation science and the translation of genomic applications into clinical practice.

    As an interdisciplinary researcher, Dr. Makhnoon has developed a research program to improve utilization of cancer prevention and control innovations across the cancer continuum, with a focus on uncertain and reclassified genetic test results. Her research interests include uncertainty related to genomic sequencing, genomic variant reclassification, and patients’ experiences with genomic sequencing. She leads a range of empirical projects focused on clinical genomics and precision medicine including cascade genetic testing, family communication of genomic information, and the ethical, legal and social implications (or ELSI) of genomics.

    Dr. Makhnoon’s research if funded primarily by the National Institutes of Health, and she is the principal investigator of a 5-year K99/R00 grant from NCI focused on multilevel investigation of uncertain and reclassified genomic variants in clinical oncology (R00CA256216). She has authored 2 textbook chapters, published numerous academic articles, and served on scientific review panels of the National Institutes of Health.

    Prior to joining UTSW in 2022, Dr. Makhnoon was a postdoctoral fellow at UT MD Anderson Cancer Center in the Division of Cancer Prevention and Population Sciences (CPRIT RP170259). She received her PhD in Public Health Genetics from the University of Washington, a MS in Genetic Epidemiology also from the University of Washington, and a BS in Biochemistry and Biotechnology from North South University.

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    Personal Note

    When she is not working, Dr. Makhnoon enjoys making science themed pottery, hiking, and travelling.

  • Research Interest
    • Cancer prevention
    • Genetic testing
    • Implementation Science
    • Public health genetics
  • Publications

    Star Featured Publications

    Are beliefs about the importance of genetics for cancer prevention and early detection associated with high risk cancer genetic testing in the U.S. Population?
    Makhnoon S, Maki KG, Yu R, Peterson SK, Shete S, Prev Med Rep 2022 Jun 27 101781
    Increasing referral of at-risk women for genetic counseling and BRCA testing using a screening tool in a community breast imaging center.
    Arun BK, Peterson SK, Sweeney LE, Bluebond RD, Tidwell RSS, Makhnoon S, Kushwaha AC, Cancer 2022 Jan 128 1 94-102
    Uptake of cancer risk management strategies among women who undergo cascade genetic testing for breast cancer susceptibility genes.
    Makhnoon S, Tran G, Levin B, Mattie KD, Dreyer B, Volk RJ, Grana G, Arun BK, Peterson SK, Cancer 2021 10 127 19 3605-3613
    Clinical management among individuals with variant of uncertain significance in hereditary cancer: A systematic review and meta-analysis.
    Makhnoon S, Bednar EM, Krause KJ, Peterson SK, Lopez-Olivo MA, Clin Genet 2021 08 100 2 119-131
    Disclosure of familial implications of pathogenic variants in breast-cancer genes to patients: Opportunity for prompting family communication.
    Makhnoon S, Smith HS, Bednar EM, Bhatt A, Turner L, Arun B, Volk RJ, Peterson SK, J Community Genet 2021 Jul 12 3 439-447
    Impact of a Genetic Evaluation Initiative to Increase Access to Genetic Services for Adolescent and Young Adults at a Tertiary Cancer Hospital.
    Makhnoon S, Corredor J, Arun B, Bell D, Yarbrough A, Livingston JA, Peterson SK, Roth M, J Adolesc Young Adult Oncol 2021 06 10 3 296-302
    The FamilyTalk randomized controlled trial: patient-reported outcomes in clinical genetic sequencing for colorectal cancer.
    Makhnoon S, Bowen DJ, Shirts BH, Fullerton SM, Larson EB, Ralston JD, Leppig KA, Crosslin DR, Veenstra D, Jarvik GP, Cancer Causes Control 2021 May 32 5 483-492
    Relationship between genetic knowledge and familial communication of CRC risk and intent to communicate CRCP genetic information: insights from FamilyTalk eMERGE III.
    Makhnoon S, Bowen DJ, Shirts BH, Fullerton SM, Meischke HW, Larson EB, Ralston JD, Leppig K, Crosslin DR, Veenstra D, Jarvik GP, Transl Behav Med 2021 03 11 2 563-572
    Factors Influencing Discussion of Cancer Genetic Testing with Health-Care Providers in a Population-Based Survey.
    Makhnoon S, Yu R, Cunningham SA, Peterson SK, Shete S, Public Health Genomics 2021 24 3-4 160-170
    Perceptions of provider's epistemic authority in response to variant of uncertain significance-related recommendations.
    Makhnoon S, Mork M, Arun B, Volk RJ, Peterson SK, J Genet Couns 2020 Oct