
Andrew Wang, M.D.
Vice Chair, Translational Research & Commercialization
Professor
Endowed Title A. Kenneth Pye Professorship in Cancer Research
School Medical School
Department Radiation Oncology
Graduate Programs Biomedical Engineering
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Biography
Andrew Z. Wang, M.D., Professor (Tenure), holds the A. Kenneth Pye Professorship in Cancer Research and is the Vice Chair for Translational Research and Commercialization in the Department of Radiation Oncology.
Dr. Wang earned two Bachelor of Science degrees in Biochemistry and Biology and a Bachelor of Arts degree in Mathematics from Indiana University with highest distinction. He obtained his medical degree from the Harvard-MIT Health Sciences and Technology (HST) program at Harvard Medical School. After an internship in internal medicine at St. Luke’s Roosevelt Hospital in New York, he completed clinical training in radiation oncology in the Harvard Radiation Oncology Program. During residency, he also completed a postdoctoral fellowship at Massachusetts Institutes of Technology under the mentorship of Dr. Robert Langer. Following residency, Dr. Wang joined the faculty of University of North Carolina as Assistant Professor in the Department of Radiation Oncology in 2009, where he rose to the rank of Tenured Professor. Dr. Wang joined UTSW faculty in 08/2021.
Dr. Wang’s research program is focused on the application of biomedical engineering to cancer research. His group aims to develop novel cancer diagnostics and therapeutics to improve cancer treatment. His work is high impact and highly innovative and has resulted in 38 patents/patent applications and three biotechnology startup companies. His work has been published in high impact journals such as Nature Nanotechnology, Advanced Materials, and Nature Biotechnology. Because of his research accomplishments, Dr. Wang has been elected as a member of the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows and the American Society for Clinical Investigation (ASCI).
Clinically, Dr. Wang specializes in the treatment of genitourinary and gastrointestinal cancers. He is familiar with different radiation techniques, including IMRT, IGRT, linac-based SRS, SBRT, and intraoperative radiotherapy and interstitial brachytherapy.
Education
- Medical School
- Harvard Medical School (2004)
- Internship
- Columbia University/St. Luke's - Roosevelt Hospital Center (2005), Internal Medicine
- Residency
- Harvard/Brigham and Women's Hospital/Massachusetts General Hospital (2009)
Research Interest
- Application of biomedical engineering to cancer research
- cancer metastasis
- Developing novel cancer diagnostics and therapeutics to improve cancer treatment
- nanomedicine
Publications
- Outcomes of surgical resection and intraoperative electron radiotherapy for patients with para-aortic recurrences of gastrointestinal and gynecologic malignancies
- Hall J, Wilson J, Shumway J, Yanagihara TK, Tepper J, Calvo B, Wang AZ, Pearlstein K, Wang K, Kim HJ Radiation Oncology 2023 Dec 18
- The role of immune cells in therapeutic angiogenesis: Concepts in tissue engineering
- Azari Z, Gorgani S, Hosseini SA, Wang AZ, Kim HW, Kargozar S Current Opinion in Biomedical Engineering 2023 Dec 28
- Nanostructured bioactive glasses: A bird's eye view on cancer therapy
- Kargozar S, Moghanian A, Rashvand A, Miri AK, Hamzehlou S, Baino F, Mozafari M, Wang AZ Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2023 Nov 15
- Chemotherapy-induced nanovaccines implement immunogenicity equivalence for improving cancer chemoimmunotherapy
- Li R, Hao Y, Roche K, Chen G, Pan W, Wang AZ, Min Y Biomaterials 2023 Oct 301
- Preliminary Evaluation of PTV Margins for Online Adaptive Radiation Therapy of the Prostatic Fossa
- Morgan HE, Wang K, Yan Y, Desai N, Hannan R, Chambers E, Cai B, Lin MH, Sher DJ, Wang J, Wang AZ, Jiang S, Timmerman R, Park C“, Garant A Practical Radiation Oncology 2023 Jul 13 e345-e353
- Effects of Bioactive Glasses (BGs) on Exosome Production and Secretion: A Critical Review
- Gorgani S, Hosseini SA, Wang AZ, Baino F, Kargozar S Materials 2023 Jun 16
- Circulating tumor cell abundance in head and neck squamous cell carcinoma decreases with successful chemoradiation and cetuximab treatment
- Poellmann MJ, Bu J, Kim DW, Iida M, Hong H, Wang AZ, Wheeler DL, Kimple RJ, Hong S Cancer Letters 2023 May 562
- Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients
- Poellmann MJ, Bu J, Liu S, Wang AZ, Seyedin SN, Chandrasekharan C, Hong H, Kim YS, Caster JM, Hong S Biosensors and Bioelectronics 2023 Apr 226
- Dynamic Cross-Task Representation Adaptation for Clinical Targets Co-Segmentation in CT Image-Guided Post-Prostatectomy Radiotherapy
- Wang F, Xu X, Yang D, Chen RC, Royce TJ, Wang A, Lian J, Lian C IEEE Transactions on Medical Imaging 2023 Apr 42 1046-1055
- Post-irradiation intratumoral heterogeneity modulates response to immune checkpoint inhibition therapy in a murine melanoma model
- Wang J, Sud S, Qu Y, Li L, Zhang J, Marron D, Knape NM, Kim IJ, Wagner KT, Zhang T, Zhao Y, Guo G, Wang AZ Neoplasia (United States) 2023 Feb 36
Books
Featured Books
Cancer Nanotherapeutics Administered by Non-Conventional Routes. In Nanotheranostics for cancer applications
Roche KC, Medik YB, Rodgers Z, Warner S, Wang AZ (2019). Springer Nature
Nanotechnology Approaches to Improving Cancer Immunotherapy. In Cancer Nanotechnology
Hagan CT 4th, Medik YB, Wang AZ (2018). Elsevier
Cancer nanotechnology in Radiation Oncology. In Precision Radiation Oncology
4. Caster JM, Zhang T, Patel AN, Newman NJ, Wang AZ (2018). Rutgers Press
Local and locally advanced rectal cancer. In Multidisciplinary Management of Gastrointestinal Cancers
O?Neil BH, Fajardo AD, Wang AZ, Shahda S (2018). World Scientific
Definitions of Biochemical Failure. In Prostate Cancer: A Comprehensive Perspective.
Zhang T, Wang AZ. (2013). Springer
Radioisotopes and Nanomedicine. In Radioisotopes: Application in Bio-medical Science
Sheets NC, Wang AZ. (2011). InTech
Nanoparticles for Cancer Diagnosis and Therapy. In Safety of Nanoparticles: From manufacturing to medical applications
Wang AZ, Gu FX, Farokhzad OC (2009). Springer
Biologically Targeted Nanoparticles as Cancer Therapeutics. In Bio-inspired Nanotechnology and Nanomaterials
Wang AZ, Radovic-Moreno AF, Farokhzad OC (2009). Nova Science Publishers
Underground Clinical Vignettes USMLE Step 2: Surgery. (4th Edition).
Kim, S.I., Swanson, T.A., Wang, AZ (Ed.) (2007). Lippincott Williams & Wilkins/Wolters Kluwer Health
Honors & Awards
- America's Top Doctors by Castle Connolly
(2020) - Elected Member of the American Society for Clinical Investigation (ASCI)
(2020) - American Institute for Medical and Biological Engineering (AIMBE) College of Fellows
(2019) - ASCO Leadership Development Program
(2019) - Associate Scientific Advisor, Science Translational Medicine
(2016-2016) - UNC Health Care and Faculty Physicians Award for Carolina Care Excellence
(2016-2021) - ASTRO Biology Basic Science Research Abstract Award
- ASTRO Junior Faculty Basic Science Research Abstract Award
- Betty and Doris Barrett Scholarship, Harvard Medical School
- Howard Hughes Medical Institute Research Fellowship for Medical Students
Professional Associations/Affiliations
- American Association for Cancer Research (AACR) (2007)
- American Society for Radiation Oncology (ASTRO) (2006)
- American Society of Clinical Oncology (ASCO) (2009)
- Associate Editor, BMC Cancer (2018)
- Journal of the National Cancer Institute, Member, Editorial Board (2017)
- Nanomedicine: Nanotechnology, Biology, and Medicine, Associate Editor (2015)
- The American Institute for Medical and Biological Engineering (AIMBE) (2019)
- The American Society for Clinical Investigation (2020)