Andrew Wang, M.D.

Andrew Z. Wang, M.D., Professor (Tenure), holds the A. Kenneth Pye Professorship in Cancer Research and is the Vice Chair for Translational Research and Commercialization in the Department of Radiation Oncology.

Dr. Wang earned two Bachelor of Science degrees in Biochemistry and Biology and a Bachelor of Arts degree in Mathematics from Indiana University with highest distinction. He obtained his medical degree from the Harvard-MIT Health Sciences and Technology (HST) program at Harvard Medical School. After an internship in internal medicine at St. Luke’s Roosevelt Hospital in New York, he completed clinical training in radiation oncology in the Harvard Radiation Oncology Program. During residency, he also completed a postdoctoral fellowship  at Massachusetts Institutes of Technology under the mentorship of Dr. Robert Langer. Following residency, Dr. Wang joined the faculty of University of North Carolina as Assistant Professor in the Department of Radiation Oncology in 2009, where he rose to the rank of Tenured Professor. Dr. Wang joined UTSW faculty in 08/2021.

Dr. Wang’s research program is focused on the application of biomedical engineering to cancer research. His group aims to develop novel cancer diagnostics and therapeutics to improve cancer treatment. His work is high impact and highly innovative and has resulted in 38 patents/patent applications  and three biotechnology startup companies. His work has been published in high impact journals such as Nature Nanotechnology, Advanced Materials, and Nature Biotechnology. Because of his research accomplishments, Dr. Wang has been elected as a member of the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows and the American Society for Clinical Investigation (ASCI).

Clinically, Dr. Wang specializes in the treatment of genitourinary and gastrointestinal cancers. He is familiar with different radiation techniques, including IMRT, IGRT, linac-based SRS, SBRT, and intraoperative radiotherapy and interstitial brachytherapy.

Medical School

Harvard Medical School (2004)

Internship

Columbia University/St. Luke's - Roosevelt Hospital Center (2005), Internal Medicine

Residency

Harvard/Brigham and Women's Hospital/Massachusetts General Hospital (2009)

• Application of biomedical engineering to cancer research
• cancer metastasis
• Developing novel cancer diagnostics and therapeutics to improve cancer treatment
• nanomedicine

Outcomes of surgical resection and intraoperative electron radiotherapy for patients with para-aortic recurrences of gastrointestinal and gynecologic malignancies

Hall J, Wilson J, Shumway J, Yanagihara TK, Tepper J, Calvo B, Wang AZ, Pearlstein K, Wang K, Kim HJ Radiation Oncology 2023 Dec 18

The role of immune cells in therapeutic angiogenesis: Concepts in tissue engineering

Azari Z, Gorgani S, Hosseini SA, Wang AZ, Kim HW, Kargozar S Current Opinion in Biomedical Engineering 2023 Dec 28

Nanostructured bioactive glasses: A bird's eye view on cancer therapy

Kargozar S, Moghanian A, Rashvand A, Miri AK, Hamzehlou S, Baino F, Mozafari M, Wang AZ Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2023 Nov 15

Chemotherapy-induced nanovaccines implement immunogenicity equivalence for improving cancer chemoimmunotherapy

Li R, Hao Y, Roche K, Chen G, Pan W, Wang AZ, Min Y Biomaterials 2023 Oct 301

Preliminary Evaluation of PTV Margins for Online Adaptive Radiation Therapy of the Prostatic Fossa

Morgan HE, Wang K, Yan Y, Desai N, Hannan R, Chambers E, Cai B, Lin MH, Sher DJ, Wang J, Wang AZ, Jiang S, Timmerman R, Park C“, Garant A Practical Radiation Oncology 2023 Jul 13 e345-e353

Effects of Bioactive Glasses (BGs) on Exosome Production and Secretion: A Critical Review

Gorgani S, Hosseini SA, Wang AZ, Baino F, Kargozar S Materials 2023 Jun 16

Circulating tumor cell abundance in head and neck squamous cell carcinoma decreases with successful chemoradiation and cetuximab treatment

Poellmann MJ, Bu J, Kim DW, Iida M, Hong H, Wang AZ, Wheeler DL, Kimple RJ, Hong S Cancer Letters 2023 May 562

Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients

Poellmann MJ, Bu J, Liu S, Wang AZ, Seyedin SN, Chandrasekharan C, Hong H, Kim YS, Caster JM, Hong S Biosensors and Bioelectronics 2023 Apr 226

Dynamic Cross-Task Representation Adaptation for Clinical Targets Co-Segmentation in CT Image-Guided Post-Prostatectomy Radiotherapy

Wang F, Xu X, Yang D, Chen RC, Royce TJ, Wang A, Lian J, Lian C IEEE Transactions on Medical Imaging 2023 Apr 42 1046-1055

Post-irradiation intratumoral heterogeneity modulates response to immune checkpoint inhibition therapy in a murine melanoma model

Wang J, Sud S, Qu Y, Li L, Zhang J, Marron D, Knape NM, Kim IJ, Wagner KT, Zhang T, Zhao Y, Guo G, Wang AZ Neoplasia (United States) 2023 Feb 36

 Featured Books

Cancer Nanotherapeutics Administered by Non-Conventional Routes. In Nanotheranostics for cancer applications

Roche KC, Medik YB, Rodgers Z, Warner S, Wang AZ (2019). Springer Nature

Nanotechnology Approaches to Improving Cancer Immunotherapy. In Cancer Nanotechnology

Hagan CT 4th, Medik YB, Wang AZ (2018). Elsevier

Cancer nanotechnology in Radiation Oncology. In Precision Radiation Oncology

4. Caster JM, Zhang T, Patel AN, Newman NJ, Wang AZ (2018). Rutgers Press

Local and locally advanced rectal cancer. In Multidisciplinary Management of Gastrointestinal Cancers

O?Neil BH, Fajardo AD, Wang AZ, Shahda S (2018). World Scientific

Definitions of Biochemical Failure. In Prostate Cancer: A Comprehensive Perspective.

Zhang T, Wang AZ. (2013). Springer

Radioisotopes and Nanomedicine. In Radioisotopes: Application in Bio-medical Science

Sheets NC, Wang AZ. (2011). InTech

Nanoparticles for Cancer Diagnosis and Therapy. In Safety of Nanoparticles: From manufacturing to medical applications

Wang AZ, Gu FX, Farokhzad OC (2009). Springer

Biologically Targeted Nanoparticles as Cancer Therapeutics. In Bio-inspired Nanotechnology and Nanomaterials

Wang AZ, Radovic-Moreno AF, Farokhzad OC (2009). Nova Science Publishers

Underground Clinical Vignettes USMLE Step 2: Surgery. (4th Edition).

Kim, S.I., Swanson, T.A., Wang, AZ (Ed.) (2007). Lippincott Williams & Wilkins/Wolters Kluwer Health

• America's Top Doctors by Castle Connolly
  (2020)
• Elected Member of the American Society for Clinical Investigation (ASCI)
  (2020)
• American Institute for Medical and Biological Engineering (AIMBE) College of Fellows
  (2019)
• ASCO Leadership Development Program
  (2019)
• Associate Scientific Advisor, Science Translational Medicine
  (2016-2016)
• UNC Health Care and Faculty Physicians Award for Carolina Care Excellence
  (2016-2021)
• ASTRO Biology Basic Science Research Abstract Award
  
• ASTRO Junior Faculty Basic Science Research Abstract Award
  
• Betty and Doris Barrett Scholarship, Harvard Medical School
  
• Howard Hughes Medical Institute Research Fellowship for Medical Students
  

• American Association for Cancer Research (AACR) (2007)
• American Society for Radiation Oncology (ASTRO) (2006)
• American Society of Clinical Oncology (ASCO) (2009)
• Associate Editor, BMC Cancer (2018)
• Journal of the National Cancer Institute, Member, Editorial Board (2017)
• Nanomedicine: Nanotechnology, Biology, and Medicine, Associate Editor (2015)
• The American Institute for Medical and Biological Engineering (AIMBE) (2019)
• The American Society for Clinical Investigation (2020)