Andrew Z. Wang, M.D., Professor (Tenure), holds the A. Kenneth Pye Professorship in Cancer Research and is the Vice Chair for Translational Research and Commercialization in the Department of Radiation Oncology.

Dr. Wang earned two Bachelor of Science degrees in Biochemistry and Biology and a Bachelor of Arts degree in Mathematics from Indiana University with highest distinction. He obtained his medical degree from the Harvard-MIT Health Sciences and Technology (HST) program at Harvard Medical School. After an internship in internal medicine at St. Luke’s Roosevelt Hospital in New York, he completed clinical training in radiation oncology in the Harvard Radiation Oncology Program. During residency, he also completed a postdoctoral fellowship  at Massachusetts Institutes of Technology under the mentorship of Dr. Robert Langer. Following residency, Dr. Wang joined the faculty of University of North Carolina as Assistant Professor in the Department of Radiation Oncology in 2009, where he rose to the rank of Tenured Professor. Dr. Wang joined UTSW faculty in 08/2021.

Dr. Wang’s research program is focused on the application of biomedical engineering to cancer research. His group aims to develop novel cancer diagnostics and therapeutics to improve cancer treatment. His work is high impact and highly innovative and has resulted in 38 patents/patent applications  and three biotechnology startup companies. His work has been published in high impact journals such as Nature Nanotechnology, Advanced Materials, and Nature Biotechnology. Because of his research accomplishments, Dr. Wang has been elected as a member of the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows and the American Society for Clinical Investigation (ASCI).

Clinically, Dr. Wang specializes in the treatment of genitourinary and gastrointestinal cancers. He is familiar with different radiation techniques, including IMRT, IGRT, linac-based SRS, SBRT, and intraoperative radiotherapy and interstitial brachytherapy.


Medical School
Harvard Medical School (2004)
Columbia University/St. Luke's - Roosevelt Hospital Center (2005), Internal Medicine
Harvard/Brigham and Women's Hospital/Massachusetts General Hospital (2009)

Research Interest

  • Application of biomedical engineering to cancer research
  • cancer metastasis
  • Developing novel cancer diagnostics and therapeutics to improve cancer treatment
  • nanomedicine


Outcomes of surgical resection and intraoperative electron radiotherapy for patients with para-aortic recurrences of gastrointestinal and gynecologic malignancies
Hall J, Wilson J, Shumway J, Yanagihara TK, Tepper J, Calvo B, Wang AZ, Pearlstein K, Wang K, Kim HJ Radiation Oncology 2023 Dec 18
The role of immune cells in therapeutic angiogenesis: Concepts in tissue engineering
Azari Z, Gorgani S, Hosseini SA, Wang AZ, Kim HW, Kargozar S Current Opinion in Biomedical Engineering 2023 Dec 28
Nanostructured bioactive glasses: A bird's eye view on cancer therapy
Kargozar S, Moghanian A, Rashvand A, Miri AK, Hamzehlou S, Baino F, Mozafari M, Wang AZ Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2023 Nov 15
Chemotherapy-induced nanovaccines implement immunogenicity equivalence for improving cancer chemoimmunotherapy
Li R, Hao Y, Roche K, Chen G, Pan W, Wang AZ, Min Y Biomaterials 2023 Oct 301
Preliminary Evaluation of PTV Margins for Online Adaptive Radiation Therapy of the Prostatic Fossa
Morgan HE, Wang K, Yan Y, Desai N, Hannan R, Chambers E, Cai B, Lin MH, Sher DJ, Wang J, Wang AZ, Jiang S, Timmerman R, Park C“, Garant A Practical Radiation Oncology 2023 Jul 13 e345-e353
Effects of Bioactive Glasses (BGs) on Exosome Production and Secretion: A Critical Review
Gorgani S, Hosseini SA, Wang AZ, Baino F, Kargozar S Materials 2023 Jun 16
Circulating tumor cell abundance in head and neck squamous cell carcinoma decreases with successful chemoradiation and cetuximab treatment
Poellmann MJ, Bu J, Kim DW, Iida M, Hong H, Wang AZ, Wheeler DL, Kimple RJ, Hong S Cancer Letters 2023 May 562
Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients
Poellmann MJ, Bu J, Liu S, Wang AZ, Seyedin SN, Chandrasekharan C, Hong H, Kim YS, Caster JM, Hong S Biosensors and Bioelectronics 2023 Apr 226
Dynamic Cross-Task Representation Adaptation for Clinical Targets Co-Segmentation in CT Image-Guided Post-Prostatectomy Radiotherapy
Wang F, Xu X, Yang D, Chen RC, Royce TJ, Wang A, Lian J, Lian C IEEE Transactions on Medical Imaging 2023 Apr 42 1046-1055
Post-irradiation intratumoral heterogeneity modulates response to immune checkpoint inhibition therapy in a murine melanoma model
Wang J, Sud S, Qu Y, Li L, Zhang J, Marron D, Knape NM, Kim IJ, Wagner KT, Zhang T, Zhao Y, Guo G, Wang AZ Neoplasia (United States) 2023 Feb 36


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Honors & Awards

  • America's Top Doctors by Castle Connolly
  • Elected Member of the American Society for Clinical Investigation (ASCI)
  • American Institute for Medical and Biological Engineering (AIMBE) College of Fellows
  • ASCO Leadership Development Program
  • Associate Scientific Advisor, Science Translational Medicine
  • UNC Health Care and Faculty Physicians Award for Carolina Care Excellence
  • ASTRO Biology Basic Science Research Abstract Award
  • ASTRO Junior Faculty Basic Science Research Abstract Award
  • Betty and Doris Barrett Scholarship, Harvard Medical School
  • Howard Hughes Medical Institute Research Fellowship for Medical Students

Professional Associations/Affiliations

  • American Association for Cancer Research (AACR) (2007)
  • American Society for Radiation Oncology (ASTRO) (2006)
  • American Society of Clinical Oncology (ASCO) (2009)
  • Associate Editor, BMC Cancer (2018)
  • Journal of the National Cancer Institute, Member, Editorial Board (2017)
  • Nanomedicine: Nanotechnology, Biology, and Medicine, Associate Editor (2015)
  • The American Institute for Medical and Biological Engineering (AIMBE) (2019)
  • The American Society for Clinical Investigation (2020)