Jie Deng, Ph.D., is a Professor in the Department of Radiation Oncology’s Division of Medical Physics & Engineering.

Prior to joining UT Southwestern, Dr. Deng was an Associate Professor of Diagnostic Radiology at Northwestern University and Rush University Medical Center. She is a certified magnetic resonance imaging (MRI) medical physicist by the American Board of Medical Physics.

Dr. Deng received her Ph.D. in biomedical engineering from Northwestern University. She also received her Master of Science in Law degree from Northwestern Pritzker Law School.

Dr. Deng has extensive clinical and research experience in MRI physics, quantitative MRI, oncological imaging, imaging processing, and AI applications in medical imaging. Specifically, she has been continuously working on clinical implementation, development, and improvement of advanced MRI technologies in tissue characterization, functional MRI for therapeutic response evaluation, AI-assisted disease diagnosis, and image quality improvement.

Research Interest

  • Adaptive radiotherapy
  • Artificial intelligence in modern radiation therapy
  • Functional oncological MRI
  • MRI-guided radiation therapy


3D cine-magnetic resonance imaging using spatial and temporal implicit neural representation learning (STINR-MR)
Shao HC, Mengke T, Deng J, Zhang Y Physics in medicine and biology 2024 May 69
Ability of dynamic gadoxetic acid-enhanced magnetic resonance imaging combined with water-specific T1 mapping to reflect inflammation in a rat model of early-stage nonalcoholic steatohepatitis
Wan Q, Peng H, Liu F, Liu X, Cheng C, Tie C, Deng J, Lyu J, Jia Y, Wang Y, Zheng H, Liang D, Liu X, Zou C Quantitative Imaging in Medicine and Surgery 2024 Feb 14 1591-1601
Rethinking the potential role of dose painting in personalized ultra-fractionated stereotactic adaptive radiotherapy
Peng H, Deng J, Jiang S, Timmerman R Frontiers in Oncology 2024 14
Bony structure enhanced synthetic CT generation using Dixon sequences for pelvis MR-only radiotherapy
Liang X, Yen A, Bai T, Godley A, Shen C, Wu J, Meng B, Lin MH, Medin P, Yan Y, Owrangi A, Desai N, Hannan R, Garant A, Jiang S, Deng J Medical physics 2023 Dec 50 7368-7382
Ultra-fast multi-parametric 4D-MRI image reconstruction for real-time applications using a downsampling-invariant deformable registration (D2R) model
Xiao H, Han X, Zhi S, Wong YL, Liu C, Li W, Liu W, Wang W, Zhang Y, Wu H, Lee HF, Cheung LY, Chang HC, Liao YP, Deng J, Li T, Cai J Radiotherapy and Oncology 2023 Dec 189
Automatic Localization of the Pons and Vermis on Fetal Brain MR Imaging Using a U-Net Deep Learning Model
Vahedifard F, Liu X, Adepoju JO, Zhao S, Ai HA, Marathu KK, Supanich M, Byrd SE, Deng J American Journal of Neuroradiology 2023 Oct 44 1191-1200
Ensemble learning and personalized training for the improvement of unsupervised deep learning-based synthetic CT reconstruction
Olberg S, Choi BS, Park I, Liang X, Kim JS, Deng J, Yan Y, Jiang S, Park JC Medical physics 2023 Mar 50 1436-1449
Image-based motion artifact reduction on liver dynamic contrast enhanced MRI
Wu Y, Liu J, White GM, Deng J Physica Medica 2023 Jan 105
MR image reconstruction from undersampled data for image-guided radiation therapy using a patient-specific deep manifold image prior
Grandinetti J, Gao Y, Gonzalez Y, Deng J, Shen C, Jia X Frontiers in Oncology 2022 Nov 12
Water Specific MRI T1 Mapping for Evaluating Liver Inflammation Activity Grades in Rats With Methionine-Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease
Wan Q, Peng H, Lyu J, Liu F, Cheng C, Qiao Y, Deng J, Zheng H, Wang Y, Zou C, Liu X Journal of Magnetic Resonance Imaging 2022 Nov 56 1429-1436

Professional Associations/Affiliations

  • American Association of Physicists in Medicine (AAPM) (2016)
  • American Society for Radiation Oncology (ASTRO) (2016)
  • International Society of Magnetic Resonance in Medicine (ISMRM) (2016)
  • Radiological Society of North America (RSNA) (2016)