Koorosh Mirpour, M.D., Ph.D. Titles and Appointments Assistant Professor School Medical School Department Neurological Surgery Biography Dr. Koorosh Mirpour is an Assistant Professor at UT Southwestern Medical Center, specializing in electrophysiology and cognitive neuroscience. With over two decades of experience in neuroscience research, Dr. Mirpour focuses on uncovering the neural mechanisms underlying Parkinson’s disease, treatment-resistant depression (TRD), and cerebellar disorders. He is currently working closely with Pouratian Lab, directed by Dr. Nader Pouratian MD, PhD, Professor of Functional Neurosurgery and Chair of the Department. Dr. Mirpour previously conducted extensive research at UCLA, where he published influential studies on visual search behavior and neuronal processing. He holds an MD and PhD in Cognitive Neuroscience from the Institute for Studies in Theoretical Physics and Mathematics (IPM). Research Interests: Dr. Mirpour's research employs advanced electrophysiological methods, including local field potentials (LFP) and single-cell recordings, to study beta-frequency oscillations within the basal ganglia and their role in motor dysfunction in Parkinson’s disease. He actively participates in pioneering research studies examining deep brain stimulation (DBS) for motor disorders and treatment-resistant depression, collaborating closely with institutions such as Baylor College of Medicine. His work integrates statistics, modeling, and machine learning techniques to investigate neural mechanisms underlying brain diseases and develop individualized treatments aimed at enhancing patient outcomes. Publications Featured Publications Interaction of motor behaviour, cortical oscillations and deep brain stimulation in Parkinson disease. Mirpour K, Pouratian N, Brain 2024 Sep Behavior in a visual search task with moving dot stimuli. Alkan Y, Mirpour K, Bisley JW, J Neurophysiol 2022 May 127 6 1564-73 Functional neuroanatomy of cognition in Parkinson's disease. Mirpour K, Wolfe C, Florence TJ, Pouratian N, Prog Brain Res 2022 269 1 289-307 Neurons in FEF Keep Track of Items That Have Been Previously Fixated in Free Viewing Visual Search. Mirpour K, Bolandnazar Z, Bisley JW, J Neurosci 2019 Mar 39 11 2114-2124 B(RAIN)2-BRAIN integrated Resource for Anatomy and Intracranial Neurophysiology. Alijanpourotaghsara A, Mirpour K, Choi JW, Chitta KK, Shalaby A, Boswell M, Chilukuri S, Cohen SL, Byon R, Benam M, Kariv S, Lee J, Duncan D, Pouratian N, Sci Data 2025 Mar 12 1 442 Aperiodic (1/f) Neural Activity Robustly Tracks Symptom Severity Changes in Treatment-Resistant Depression. Hacker C, Mocchi MM, Xiao J, Metzger B, Adkinson J, Pascuzzi B, Mathura R, Oswalt D, Watrous A, Bartoli E, Allawala A, Pirtle V, Fan X, Danstrom I, Shofty B, Banks G, Zhang Y, Armenta-Salas M, Mirpour K, Provenza N, Mathew S, Cohn JF, Borton D, Goodman W, Pouratian N, Sheth SA, Bijanki KR, Biol Psychiatry Cogn Neurosci Neuroimaging 2025 Feb 10 2 186-194 Suppression of frontal eye field neuronal responses with maintained fixation. Mirpour K, Bolandnazar Z, Bisley JW, Proc Natl Acad Sci U S A 2018 Jan 115 4 804-809 Results 1-7 of 7 1