Biography

2021-Present: Assistant Professor, UT Southwestern Medical Center, Dallas, TX

2016-2021: Postdoctoral Fellow (EMBO, HFSP Long-Term Postdoctoral Fellow), The Francis Crick Institute, London, UK

2015-2016: Postdoctoral Fellow (JSPS SPD), The Institute of Medical Science, The University of Tokyo, Japan

2010-2015: Graduate student, Graduate school of Medicine, Chiba University, Japan

Research Interest

  • Inter-organ Communication
  • Intestinal Neural Circuits
  • Neuro-Immune Circuits

Publications

Featured Publications LegendFeatured Publications

Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon.
Nakamura A, Kurihara S, Takahashi D, Ohashi W, Nakamura Y, Kimura S, Onuki M, Kume A, Sasazawa Y, Furusawa Y, Obata Y, Fukuda S, Saiki S, Matsumoto M, Hase K, Nat Commun 2021 04 12 1 2105
Enteric glia as a source of neural progenitors in adult zebrafish.
McCallum S, Obata Y, Fourli E, Boeing S, Peddie CJ, Xu Q, Horswell S, Kelsh RN, Collinson L, Wilkinson D, Pin C, Pachnis V, Heanue TA, Elife 2020 08 9
Linking neurons to immunity: Lessons from Hydra.
Obata Y, Pachnis V, Proc Natl Acad Sci U S A 2020 08 117 33 19624-19626
Commensal-bacteria-derived butyrate promotes the T-cell-independent IgA response in the colon.
Isobe J, Maeda S, Obata Y, Iizuka K, Nakamura Y, Fujimura Y, Kimizuka T, Hattori K, Kim YG, Morita T, Kimura I, Offermanns S, Adachi T, Nakao A, Kiyono H, Takahashi D, Hase K, Int Immunol 2020 04 32 4 243-258
Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice.
Kimura S, Kobayashi N, Nakamura Y, Kanaya T, Takahashi D, Fujiki R, Mutoh M, Obata Y, Iwanaga T, Nakagawa T, Kato N, Sato S, Kaisho T, Ohno H, Hase K, J Exp Med 2019 04 216 4 831-846
NALT M cells are important for immune induction for the common mucosal immune system.
Date Y, Ebisawa M, Fukuda S, Shima H, Obata Y, Takahashi D, Kato T, Hanazato M, Nakato G, Williams IR, Hase K, Ohno H, Int Immunol 2017 12 29 10 471-478
The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System.
Obata Y, Pachnis V, Gastroenterology 2016 11 151 5 836-844

Honors & Awards

  • HFSP Long-Term Fellowship
    (2017-2020)
  • EMBO Long-Term Fellowship
    (2016-2017)
  • Inoue Research Award for Young Scientists
    Inoue Foundation for Science (2016)
  • Ikushi Prize
    Japan Society for the Promotion of Science (JSPS) (2015)
  • Superlative Postdoctoral Fellow (SPD)
    Japan Society for the Promotion of Science (JSPS) (2015-2016)