Ying Xian, M.D., Ph.D. Section Head Research, Stroke & Cerebrovascular Diseases Associate Professor School Medical School Department Neurology Biography Joined UT Southwestern: 2021 Ying Xian, M.D., Ph.D., FAHA, is a tenured Associate Professor in the Department of Neurology at UT Southwestern Medical Center. Research: For more than a decade, Dr. Xian’s research has been focused on improving healthcare quality and outcomes in patients with cardiovascular disease and stroke. Before joining the UT Southwestern faculty in 2021, Dr. Xian served as the clinical lead for the AHA/ASA Get With The Guidelines Stroke (GWTG-Stroke) Registry and Society of Thoracic Surgeons (STS) National Database Analytical Center at Duke. He has led multiple groundbreaking comparative effectiveness and patient-centered outcomes research projects, with extensive experience with large national registries and data linkage with Medicare claims. Dr. Xian has authored or co-authored over 200 peer-reviewed publications and ranks among the World's Top 2% Scientists in clinical medicine by Stanford/Elsevier. He is the Principal Investigator of the National Institute on Aging (NIA) funded R01s to evaluate antithrombotic therapy for secondary stroke prevention and post-stroke dementia, and the AHA Clinical Research Program and Scientist Development Grant to investigate off-label/off-guideline thrombolytic therapy in stroke. Affiliations & Awards: He has been recognized for his research through the AHA QCOR Young Investigator Award and the Northwestern Junior Faculty Clinical Research Award. Dr. Xian has served on multiple committees of the AHA/ASA, including the GWTG Quality Improvement Subcommittee, Stroke Systems of Care Advisory Group, Stroke Council’s Quality and Outcomes Committee, Quality of Care and Outcomes Research (QCOR) Council’s Young Clinicians & Investigators Committee, and GWTG-Stroke Clinical Work Group. Background: Dr. Xian earned his medical degree at Beijing Medical University (Peking University Health Science Center), completed a residency in Internal Medicine, and a fellowship in Cardiology at Peking University People’s Hospital, and Fuwai Hospital, Peking Union Medical College. Dr. Xian obtained his Ph.D. degree in Health Services Research and Policy at the University of Rochester and received the American Heart Association/American Stroke Association (AHA/ASA) Pharmaceutical Roundtable-Spina Fellowship training in Cardiovascular Outcomes Research at Duke University. Research Interest Cardiovascular disease Cognitive impairment and dementia Comparative effectiveness research Global health Health services research Outcomes research Patient-centered outcomes research Primary and secondary prevention Quality improvement Stroke Publications Prediction of Large Vessel Occlusion Stroke Using Clinical Registries for Research de Havenon A, Ayodele I, Alhanti B, Mac Grory B, Xian Y, Fonarow G, Smith EE, Worrall BB Neurology 2024 Jun 102 e209424 Time to Anticoagulation Reversal and Outcomes after Intracerebral Hemorrhage Sheth KN, Solomon N, Alhanti B, Messe SR, Xian Y, Bhatt DL, Hemphill JC, Frontera JA, Chang RC, Danelich IM, Huang J, Schwamm L, Smith EE, Goldstein JN, Mac Grory B, Fonarow GC, Saver JL JAMA neurology 2024 Apr 81 363-372 Trends in Stroke Thrombolysis Care Metrics and Outcomes by Race and Ethnicity, 2003-2021 Man S, Solomon N, Mac Grory B, Alhanti B, Saver JL, Smith EE, Xian Y, Bhatt DL, Schwamm LH, Uchino K, Fonarow GC JAMA Network Open 2024 Feb 7 E2352927 Higher Procedural Volumes Are Associated with Faster Treatment Times, Better Functional Outcomes, and Lower Mortality in Patients Undergoing Endovascular Treatment for Acute Ischemic Stroke Nogueira RG, Haussen DC, Smith EE, Sun JL, Xian Y, Alhanti B, Blanco R, Mac Grory B, Doheim MF, Bhatt DL, Fonarow GC, Hassan AE, Joundi RA, Mocco J, Frankel MR, Schwamm LH Annals of Neurology 2024 Jan 95 146-155 Thrombolysis for ischaemic stroke despite direct oral anticoagulation Purrucker JC, Meinel TR, Wilson D, Xian Y, Wu TY, Seiffge DJ Stroke and Vascular Neurology 2024 Performance of Thrombectomy-Capable, Comprehensive, and Primary Stroke Centers in Reperfusion Therapies for Acute Ischemic Stroke: Report From the Get With The Guidelines-Stroke Registry Raychev R, Sun JL, Schwamm L, Smith EE, Fonarow GC, Messé SR, Xian Y, Chiswell K, Blanco R, Mac Grory B, Saver JL Circulation 2023 Dec 148 2019-2028 Association between perceived risk of Alzheimer's disease and related dementias and cognitive function among U.S. older adults Wang N, Xu H, West JS, Østbye T, Wu B, Xian Y, Dupre ME Archives of Gerontology and Geriatrics 2023 Dec 115 Atrial fibrillation as a novel risk factor for retinal stroke: A protocol for a population-based retrospective cohort study Lusk JB, Wilson L, Nalwade V, Song A, Schrag M, Biousse V, Li F, Poli S, Piccini J, Xian Y, O’Brien E, Grory BM PloS one 2023 Dec 18 Traditional Chinese Medicine Compound (Tongxinluo) and Clinical Outcomes of Patients with Acute Myocardial Infarction: The CTS-AMI Randomized Clinical Trial Yang Y, Li X, Chen G, Xian Y, Zhang H, Wu Y, Yang Y, Wu J, Wang C, He S, Wang Z, Wang Y, Wang Z, Liu H, Wang X, Zhang M, Zhang J, Li J, An T, Guan H, Li L, Shang M, Yao C, Han Y, Zhang B, Gao R, Peterson ED JAMA 2023 Oct 330 1534-1545 Vitamin K Antagonists and Intracranial Hemorrhage after Endovascular Thrombectomy - Reply Mac Grory B, Xian Y JAMA 2023 Oct 330 1490-1491 Results 1-10 of 226 1 2 3 4 5 Next Last Books Featured Books Data Resources. In Understanding Clinical Research Renato Lopes and Robert Harrington (2013). McGraw-Hill Education / Medical Honors & Awards 2nd Place Winner, Junior Faculty Clinical Category Young Investigator Research Award12th Annual Northwestern Cardiovascular Young Investigators' Forum (2016) FellowAmerican Heart Association (2016) Travel AwardInternational Stroke Conference (2016) Distinguished Clinical Research Achievement AwardClinical Research Forum. Fonarow GC, Zhao X, Smith EE, Saver JL, Reeves MJ, Bhatt DL, Xian Y, Hernandez AF, Peterson ED, and Schwamm LH. Door-to-needle times for tissue plasminogen activator administration and clinical outcomes in acute ischemic stroke before and after a quality improvement initiative. JAMA. 2014, 311(16), 1632-1640 (2015) 2nd Place Winner, Junior Faculty Clinical Track10th Annual Northwestern Cardiovascular Young Investigators' Forum (2014) Young Investigator FinalistAmerican Heart Association Epidemiology and Prevention|Nutrition, Physical Activity and Metabolism Scientific Sessions (2011) Young Investigator AwardAmerican Heart Association Quality of Care and Outcomes Research Interdisciplinary Council (2010) Bertram Scott Research FellowAmerican Heart Association Founders Affiliate (2008) Predoctoral FellowshipAmerican Heart Association Founders Affiliate (2008) Excellus Fellowship in Health Services Research and PolicyExcellus BCBS (2005) Dean's FellowshipUniversity of Rochester (2003) Professional Associations/Affiliations African Stroke Organization (2021) Alzheimer's Association (2024) American Heart Association (2007) European Stroke Organisation (2018) Gerontological Society of America (2021) World Stroke Organization (2019)