Bin Cai, Ph.D.

Bin Cai, Ph.D., is an Associate Professor and Director of Advanced Physics Service in UT Southwestern Medical Center’s Department of Radiation Oncology’s Division of Medical Physics & Engineering.

Dr. Cai received his Ph.D. from Ohio University and completed his medical physics residency training at Washington University’s School of Medicine. Prior to joining UT Southwestern, Dr. Cai was an Assistant Professor of Radiation Oncology at Washington University. He is certified in therapeutic radiological physics by the American Board of Radiology.

Dr. Cai has extensive clinical and research experience in radiation therapeutic physics, imaging processing, and computational programming. Specifically, Dr. Cai has been continuously working on clinical implementation, development, and improvement of advanced radiation therapy treatment technologies and procedures, including both MR and CT online adaptive radiotherapy, biology-guided radiotherapy, AI-assisted radiotherapy process, automated quality assurance, as well as risk analysis/process improvement for radiotherapy workflow.

Graduate School

Ohio University (2011), Arts and Science

• Adaptive radiotherapy
• Automation and artificial intelligence in modern radiation therapy
• Biology-guided radiotherapy
• MR-guided radiotherapy

BIOGUIDE-X: A First-in-Human Study of the Performance of Positron Emission Tomography-Guided Radiation Therapy

Vitzthum LK, Surucu M, Gensheimer MF, Kovalchuk N, Han B, Pham D, Chang D, Shirvani SM, Aksoy D, Maniyedath A, Narayanan M, Da Silva AJ, Mazin S, Feghali KA, Iyengar P, Dan T, Pompos A, Timmerman R, Öz O, Cai B, Garant A International Journal of Radiation Oncology Biology Physics 2024 Apr 118 1172-1180

Simulation and pre-planning omitted radiotherapy (SPORT): a feasibility study for prostate cancer

Zhuang T, Parsons D, Desai N, Gibbard G, Keilty D, Lin MH, Cai B, Nguyen D, Chiu T, Godley A, Pompos A, Jiang S Biomedical Physics and Engineering Express 2024 Mar 10

Preliminary Evaluation of PTV Margins for Online Adaptive Radiation Therapy of the Prostatic Fossa

Morgan HE, Wang K, Yan Y, Desai N, Hannan R, Chambers E, Cai B, Lin MH, Sher DJ, Wang J, Wang AZ, Jiang S, Timmerman R, Park C“, Garant A Practical Radiation Oncology 2023 Jul 13 e345-e353

Phantom-based Quality Assurance of a Clinical Dose Accumulation Technique Used in an Online Adaptive Radiation Therapy Platform

Maraghechi B, Mazur T, Lam D, Price A, Henke L, Kim H, Hugo GD, Cai B Advances in Radiation Oncology 2023 May 8

Toward real-time automatic treatment planning (RTTP) with a one-step 3D fluence map prediction method and (nonorthogonal) convolution technique

Peng J, Yang C, Guo H, Shen L, Zhang M, Wang J, Zhang Z, Cai B, Hu W Computer Methods and Programs in Biomedicine 2023 Apr 231

Clinical experience on patient-specific quality assurance for CBCT-based online adaptive treatment plan

Shen C, Chen L, Zhong X, Gonzalez Y, Visak J, Meng B, Inam E, Parsons D, Godley A, Jiang S, Cai B, Lin MH Journal of applied clinical medical physics 2023 Apr 24

Evaluation of fan-beam kilovoltage computed tomography image quality on a novel biological-guided radiotherapy platform

Zhuang T, Gibbard G, Duan X, Tan J, Park Y, Lin MH, Sun Z, Oderinde OM, Lu W, Reynolds R, Godley A, Pompos A, Dan T, Garant A, Iyengar P, Timmerman R, Jiang S, Cai B Physics and Imaging in Radiation Oncology 2023 Apr 26

On the feasibility of improved target coverage without compromising organs at risk using online adaptive stereotactic partial breast irradiation (A-SPBI)

Montalvo SK, Kim N, Nwachukwu C, Alluri P, Parsons D, Lin MH, Cai B, Zhuang T, Hrycushko B, Chen L, Timmerman R, Rahimi A Journal of applied clinical medical physics 2023 Feb 24

Prospective imaging comparison of anatomic delineation with rapid kV cone beam CT on a novel ring gantry radiotherapy device

Henke LE, Fischer-Valuck BW, Rudra S, Wan L, Samson PS, Srivastava A, Gabani P, Roach MC, Zoberi I, Laugeman E, Mutic S, Robinson CG, Hugo GD, Cai B, Kim H Radiotherapy and Oncology 2023 Jan 178

Simulated computed tomography-guided stereotactic adaptive radiotherapy (CT-STAR) for the treatment of locally advanced pancreatic cancer

Schiff JP, Price AT, Stowe HB, Laugeman E, Chin RI, Hatscher C, Pryser E, Cai B, Hugo GD, Kim H, Badiyan SN, Robinson CG, Henke LE Radiotherapy and Oncology 2022 Oct 175 144-151

• American Association of Physicists in Medicine (AAPM) (2012)
• American Society for Radiation Oncology (ASTRO) (2016)
• Radiation Research Society (RRS) (2016)