Raksha Jain, M.D.
Associate Professor

Endowed Title Dedman Family Scholar in Clinical Care

Department Internal Medicine

Graduate Programs Molecular Microbiology

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Biography

Raksha Jain, M.D., is an Associate Professor in UT Southwestern Medical Center's Department of Internal Medicine and is a Dedman Family Scholar in Clinical Care. She is also the Medical Director of the Adult Cystic Fibrosis Program.

She has earned awards from the National Institutes of Health, Children’s Medical Center of Dallas, and the Cystic Fibrosis Foundation for her work on hormonal influences of lung disease in cystic fibrosis.

Dr. Jain obtained her bachelor of science degree at the Massachusetts Institute of Technology in molecular biology and received her medical degree at the University of Texas Houston Health Science Center. She completed her residency and chief residency in internal medicine at UT Southwestern and moved to Washington University in St. Louis for her fellowship in pulmonary and critical care medicine.

She oversees multicenter clinical trials related to cystic fibrosis and conducts her own clinical and molecular scientific research. Her research interests include new treatments for cystic fibrosis and gender disparities in airway diseases.

Dr. Jain is board certified in pulmonology, critical care medicine, and internal medicine by the American Board of Internal Medicine.

Education

Medical School: UT Health Science Center at Houston (2001)
Residency: UT Southwestern Medical Center (2004), Internal Medicine
Residency: UT Southwestern Medical Center (2005), Internal Medicine
Fellowship: Washington University School of Medicine (2009), Pulmonary Diseases & Critical Care Medicine
Graduate School: Washington University School of Medicine (2010), Clinical Investigation
Other Post Graduate Training: Washington University School of Medicine (2010)
Other Post Graduate Training: Washington University School of Medicine (2010)
Graduate School: Washington University School of Medicine (2010)

Research Interest

Gender disparities in lung diseases
Sex hormone influence on host immunity
Treatment advances for Cystic Fibrosis

Publications

Featured Publications

17ß-estradiol dysregulates innate immune responses to Pseudomonas aeruginosa respiratory infection and is modulated by estrogen receptor antagonism.: Abid S, Xie S, Bose M, Shaul PW, Terada LS, Brody SL, Thomas PJ, Katzenellenbogen JA, Kim SH, Greenberg DE, Jain R Infect. Immun. 2017 Aug
Lung transplantation and gender effects on survival of recipients with cystic fibrosis.: Raghavan D, Gao A, Ahn C, Kaza V, Finklea J, Torres F, Jain R J. Heart Lung Transplant. 2016 Jun
Gender differences in outcomes of patients with cystic fibrosis.: Harness-Brumley CL, Elliott AC, Rosenbluth DB, Raghavan D, Jain R J Womens Health (Larchmt) 2014 Dec 23 12 1012-20
Effects of puberty on cystic fibrosis related pulmonary exacerbations in women versus men.: Sutton S, Rosenbluth D, Raghavan D, Zheng J, Jain R Pediatr. Pulmonol. 2013 Mar
Sex Hormone-Dependent Regulation of Cilia Beat Frequency in Airway Epithelium.: Jain R, Ray JM, Pan JH, Brody SL American journal of respiratory cell and molecular biology 2011 Oct
Temporal relationship between primary and motile ciliogenesis in airway epithelial cells.: Jain R, Pan J, Driscoll JA, Wisner JW, Huang T, Gunsten SP, You Y, Brody SL Am. J. Respir. Cell Mol. Biol. 2010 Dec 43 6 731-9
Azithromycin is associated with increased survival in lung transplant recipients with bronchiolitis obliterans syndrome.: Jain R, Hachem RR, Morrell MR, Trulock EP, Chakinala MM, Yusen RD, Huang HJ, Mohanakumar T, Patterson GA, Walter MJ J. Heart Lung Transplant. 2010 May 29 5 531-7
Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor-mediated production of TGF-beta1.: Jain R, Shaul PW, Borok Z, Willis BC Am. J. Respir. Cell Mol. Biol. 2007 Jul 37 1 38-47
AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo.: Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller B, Greenberg D, ACS Infect Dis 2019 May
Impact of high- versus low-risk genotype on sinonasal radiographic disease in cystic fibrosis.: Halderman AA, Lee S, London NR, Day A, Jain R, Moore JA, Lin SY Laryngoscope 2018 Dec

Honors & Awards

CFF Foundation Harry Shwachman Clinical Research Award
(2015-2018)
LEAD Capstone Dean's Recognition Award - U.T. Southwestern Medical Center
(2015)
CREW award recipient
(2010)
Dedman Family Scholar in Clinical Care
(2010)
American Thoracic Society Career Development Award
(2009)
Multidisciplinary Clinical Research Career Development Award
(2009)
University of Texas Houston Health Science Center Gold Headed Cane Award
Humanism in Medicine (2001)

Professional Associations/Affiliations

Society for Women's Health Research (2012)
Association for Clinical and Translational Science (2009)
American College of Chest Physicians
American Thoracic Society
Dallas County Medical Society
Texas Medical Association