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Raksha Jain, M.D.

Raksha Jain, M.D.

Titles and Appointments

Medical Director, Adult Cystic Fibrosis Program

Professor

Endowed Title
Dedman Family Scholar in Clinical Care
School
Medical School
Department
Internal Medicine
Graduate Programs
Molecular Microbiology

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Raksha Jain, M.D., M.S.C.I., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Pulmonary and Critical Care Medicine. A Dedman Family Scholar in Clinical Care, she also serves as Medical Director of the Adult Cystic Fibrosis Program.

    Originally from Dallas, Dr. Jain holds a bachelor's degree in molecular biology from the Massachusetts Institute of Technology in Cambridge, Massachusetts. She received her medical degree from the University of Texas Houston Health Science Center and completed internal medicine residency training at UT Southwestern Medical Center, where she served as Chief Resident. She then obtained advanced training through a fellowship in pulmonary and critical care at Washington University School of Medicine in St. Louis, where she also earned a master's degree in clinical investigation.

    Certified in pulmonology, critical care medicine, and internal medicine, by the American Board of Internal Medicine, Dr. Jain joined the UT Southwestern faculty in 2010. 

    Dr. Jain's research interests include new treatments for cystic fibrosis and gender disparities in airway diseases. She oversees multicenter clinical trials related to cystic fibrosis and conducts her own clinical and molecular scientific research. She has earned awards from the National Institutes of Health, Children’s Medical Center of Dallas, and the Cystic Fibrosis Foundation for her work on hormonal influences of lung disease in cystic fibrosis.

    At UT Southwestern, Dr. Jain is a member of various committees, including the Ambulatory Clinic Medical Directors Committee, the Department of Medicine Clinical Trials Working Group, and the Aston Clinical Research Operations Working Group. She is also the Chair of the Department of Medicine Clinical Scholars Incentive Plan Committee. 

    Dr. Jain is active in several professional societies, including the American Thoracic Society, the American College of Chest Physicians, the Texas Medical Association, the Dallas County Medical Society, the Society of Women's Health Research, the American Medical Association, the Southern Society for Clinical Investigation, and the European Cystic Fibrosis Society.

    Outside of UT Southwestern, Dr. Jain is the Chair of the Sexual Health, Reproduction, and Gender Researching Working Group through the Cystic Fibrosis Foundation Therapeutics Development Network.

  • Education
    Medical School
    University of Texas Health Science Center at Houston (2001)
    Residency
    UT Southwestern Medical Center (2004), Internal Medicine
    Residency
    UT Southwestern Medical Center (2005), Internal Medicine
    Fellowship
    Washington University School of Medicine (2009), Pulmonary Diseases & Critical Care Medicine
    Graduate School
    Washington University School of Medicine (2010)
    Other Post Graduate Training
    Washington University School of Medicine (2010)
    Other Post Graduate Training
    Washington University School of Medicine (2010)
    Graduate School
    Washington University School of Medicine (2010), Clinical Investigation
  • Research Interest
    • Gender disparities in lung diseases
    • Sex hormone influence on host immunity
    • Treatment advances for Cystic Fibrosis
  • Publications
    Impact of Cystic Fibrosis Transmembrane Conductance Regulator Modulators on Maternal Outcomes During and After Pregnancy
    Jain R, Peng G, Lee MJ, Keller A, Cosmich S, Reddy S, West NE, Kazmerski TM, Goralski JL, Flume PA, Roe AH, Hadjiliadis D, Uluer A, Mody S, Ladores S, Taylor-Cousar JL CHEST 2025 Feb 167 348-361
    Learning from the CFTR modulator baby boom
    Jain R, Goralski JL Journal of Cystic Fibrosis 2025
    Lentiviral Gene Therapy for Cystic Fibrosis A Promising Approach and First-in-Human Trial
    Davies JC, Polineni D, Boyd AC, Donaldson S, Gill DR, Griesenbach U, Hyde SC, Jain R, McLachlan G, Mall MA, Alton EW American journal of respiratory and critical care medicine 2024 Dec 210 1398-1408
    Outcomes in Black People with Cystic Fibrosis: A Registry Analysis
    Devarajan SR, Staggers KA, Wu TD, Jain R Annals of the American Thoracic Society 2024 Dec 21 1778-1781
    Pregnancy and fertility in people with cystic fibrosis following lung transplantation
    Taylor-Cousar JL, Sole A, Jain R Current Opinion in Pulmonary Medicine 2024 Nov 30 652-659
    Impact of Discontinuing Both Hypertonic Saline and Dornase Alfa after Elexacaftor-Tezacaftor-Ivacaftor in Cystic Fibrosis
    Mayer-Hamblett N, Gifford AH, Kloster M, Russell R, Braun AT, Gibson RL, Hoppe JE, Jain R, Linnemann RW, Liou TG, Lysinger J, Milla C, Riekert KA, Sawicki GS, Young J, Nichols D Annals of the American Thoracic Society 2024 Nov 21 1507-1515
    Sex Differences After Treatment With Ivacaftor in People With Cystic Fibrosis
    Holtrop M, Cosmich S, Lee MJ, Keller A, Jain R CHEST 2024 Nov 166 951-962
    Forced Expiratory Volume in 1 Second Variability Predicts Lung Transplant or Mortality in People with Cystic Fibrosis in the United States
    Todd JV, Morgan WJ, Szczesniak RD, Ostrenga JS, O’Connell OJ, Cromwell EA, Faro A, Jain R Annals of the American Thoracic Society 2024 Oct 21 1416-1420
    Concentrations of dehydroepiandrosterone-sulphate (DHEA-S) in people with cystic fibrosis on and off elexacaftor-tezacaftor-ivacaftor
    Abid S, Shaffer L, Bayat A, Lee M, Keller A, Jain R Journal of Cystic Fibrosis 2024 Sep 23 874-877
    Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol
    Kazmerski TM, Stransky OM, Lee MJ, Prangley KA, Jain R, Georgiopoulos AM, Shaw DS, Taylor-Cousar J BMJ Open Respiratory Research 2024 Aug 11
  • Honors & Awards
    • CFF Foundation Harry Shwachman Clinical Research Award
      (2015-2018)
    • LEAD Capstone Dean's Recognition Award - U.T. Southwestern Medical Center
      (2015)
    • CREW award recipient
      (2010)
    • Dedman Family Scholar in Clinical Care
      (2010)
    • American Thoracic Society Career Development Award
      (2009)
    • Multidisciplinary Clinical Research Career Development Award
      (2009)
    • University of Texas Houston Health Science Center Gold Headed Cane Award
      Humanism in Medicine (2001)
  • Professional Associations/Affiliations
    • American College of Chest Physicians
    • American Thoracic Society
    • Association for Clinical and Translational Science (2009)
    • Dallas County Medical Society
    • Society for Women's Health Research (2012)
    • Texas Medical Association