Jason Fleming, M.D. Deputy Dir Clinical Affairs Sccc Professor School Medical School Department Harold C. Simmons Comprehensive Cancer Center | Surgery You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Jason B. Fleming, M.D., is a Professor in the Department of Surgery at UT Southwestern Medical Center. He is an internationally recognized surgical oncologist specializing in pancreatic cancer and serves as Deputy Director for Clinical Affairs of the Harold C. Simmons Comprehensive Cancer Center. Dr. Fleming earned his medical degree at the University of Tennessee Center of Health Science. He completed a clinical residency in general surgery and a research fellowship in cancer research at UT Southwestern and the Hamon Center for Therapeutic Oncology Research. He also completed a clinical fellowship in surgical oncology at the University of Texas MD Anderson Cancer Center. Certified by the American Board of Surgery, he rejoined the UT Southwestern faculty in 2024. He previously spent six years as an Assistant and Associate Professor in UT Southwestern’s Department of Surgery, from 1999 to 2006 . Before his return to UT Southwestern, Dr. Fleming served as a Professor of Surgical Oncology and Chief of Pancreas Surgery at MD Anderson and then as Chair of the Department of Gastrointestinal Oncology at the Moffitt Cancer Center in Tampa, Florida. At UT Southwestern, Dr. Fleming directs all clinical operations at the Simmons Comprehensive Cancer Center (SCCC) and drives strategies to advance innovative, patient-centered cancer care across the health system. His goal is to promote and further establish SCCC as a national leader in multidisciplinary, evidence-based patient care, cancer clinical trials, and novel treatment approaches. He is a prolific academician, with over 300 peer-reviewed publications and contributions to numerous books. He has delivered many international, national, and regional invited lectures. He serves as principal investigator or co-investigator for numerous active research projects, with grant support from sources such as the National Institutes of Health, the National Cancer Institute, and the U.S. Army Medical Research Acquisition Activity’s Pancreatic Cancer Research Program. Dr. Fleming is a Fellow of the American College of Surgeons and a member of numerous other professional organizations, including the American Society of Clinical Oncology, the Society of Surgical Oncology, and the American Association for Cancer Research. He also serves on the editorial board for the journal Surgery Open Science and serves as an ad hoc reviewer for several other scholarly journals. The recipient of numerous awards, he has been named a Castle Connolly Top Doctor every year since 2013. When he’s not at work, Dr. Fleming is an avid reader of history and is learning game design. Most importantly, he enjoys spending time with friends and family. Education Medical School University of Tennessee Health Science Center (1990) Internship UT Southwestern Medical Center (1991) Research Fellowship UT Southwestern Medical Center (1995), Surgical Oncology Residency UT Southwestern Medical Center (1997), General Surgery Fellowship UT MD Anderson Cancer Center (1999) Research Interest Pancreatic Cancer Books Featured Books Current issues of borderline resectable pancreatic ductal adenocarcinoma. In Pancreatic Cancer, With Special Focus on Topical Issues and Surgical Techniques Denbo JW, Fleming JB (2017). Berlin, Springer-Verlag Definition and management of borderline resectable pancreatic cancer. In Pancreatic Cancer and Periampullary Neoplasms Denbo JW, Fleming JB (2016). Philadelphia,, Elsevier Molecular and genetic basis of pancreatic carcinogenesis: Which concepts may be clinically relevant. In Pancreatic Neoplasms Bernard V, Fleming JB, Maitra A (2016). Philadelphia, Elsevier Pancreatic cancer (exocrine). In 60 Years of Survival Outcomes at The University of Texas MD Anderson Cancer Center Fleming JB, Katz M, Hwang R, Varadhachary G (2013). New York, Springer Patient-derived xenograft model of pancreatic cancer. In Patient Derived Tumor Xenograft Models Rios Perez MV, Fleming JB (2016). United Kingdom, Elsevier Complex General Surgical Oncology: A Case-Based Approach Abbott DE, Fleming JB (2014). London, Future Medicine Ltd Cystic pancreatic lesions. In Oncologic Imaging: A Multidisciplinary Approach Bhosale P, Fleming JB, Das P, Javle M, Lee JH (2012). Philadelphia, Elsevier Pancreatic ductal adenocarcinoma. In Oncologic Imaging: A Multidisciplinary Approach Tamm EP, Fleming JB, Varadhachary GR (2012). Philadelphia, Elsevier Imaging of pancreatic adenocarcinoma: Update on staging/resectability. In Pancreatic Imaging, Radiologic Clinics of North America Tamm EP, Balachandran A, Bhosale PR, Katz MH, Fleming JB, Lee JH, Varadhachary GR (2012). Saunders Surgical management of sporadic gastrointestinal neuroendocrine tumors. In Neuroendocrine Tumors Callender GG, Fleming JB (2011). New York, Springer Borderline resectable pancreatic adenocarcinoma. In Pancreatic Cancer Katz MHG, Fleming JB, Lee JE, Pisters PWT (2011). New Delhi, India, Elsevier The recognition and surgical management of heritable lesions of the pancreas. In Surgical Oncology Clinics of North America Kim MP, Evans DP, Vu TM, Fleming JB (2009). Philadelphia, W.B. Saunders Advanced therapy in surgical oncology. In Gastric Cancer Chapter Fleming JB (2008). BC Decker Inc Unusual pancreatic tumors. In Current Surgical Therapy Phillips K, Fleming JB, Tamm EP, Evans DB (2008). Philadelphia, Mosby Elsevier Laparoscopy in the evaluation of patients with upper gastrointestinal malignancies. In Laparoscopic Surgery: Principles and Procedures Fleming JB (2001). Marcel Dekker Pancreas in Selected Readings. In General Surgery Fleming JB (2001). Cell signaling pathways in pancreatic cancer. In M.D. Anderson Solid Tumor Oncology Series: Pancreatic Cancer Fleming JB (2000). Springer-Verlag Sarcoma and lymphoma. In Selected Readings in General Surgery Fleming JB (2000). General oncology. In Selected Readings in General Surgery Fleming JB (1999). Signal transduction pathways in pancreatic cancer. In Methods in Molecular Medicine: Molecular Biology of Pancreatic Cancer Fleming JB, Breslin T, Evans D, Chiao P (1998). Humana Press Collected letters in surgery. In Question No. 651: Papillary Thyroid Cancer in Pregnancy Fleming JB, Evans D (1997). Radiation injury. In The Parkland Trauma Handbook Fleming JB (1994). CV Mosby Honors & Awards Jack Kolosky AwardMoffitt First Connect (2021) Moffitt Telly AwardMCC 360 Patient Experience Video (2020) Best Doctors In AmericaBest Doctors List (2019-2020) InductionAmerican College of Surgeons Master Surgeon Educators (2019) Top DoctorInternational Association of HealthCare Professionals (2018) Castle Connolly Top DoctorAmerican Registry, LLC and Castle Connolly Medical Ltd. (2013) Guide to America's Top SurgeonsConsumer Research Council of America (2012) Texas Super DoctorsTexas Monthly (2011) Professional Associations/Affiliations American Association for Cancer Research American College of Surgeons American Radium Society American Society of Clinical Oncology American Surgical Association Pancreas Club Society for Surgery of the Alimentary Tract Society of Surgical Oncology Society of University Surgeons Southern Surgical Society Western Surgical Society
