Research Interest

  • DNA replication
  • Fluorescence imaging
  • Liquid-liquid phase separation
  • Protein intrinsic disorder

Publications

Featured Publications LegendFeatured Publications

Effect of C-terminal sequence on competitive semaphorin binding to neuropilin-1.
Parker MW, Linkugel AD, Vander Kooi CW, Journal of molecular biology 2013 Nov 425 22 4405-14
Mechanistic basis for the potent anti-angiogenic activity of semaphorin 3F.
Guo HF, Li X, Parker MW, Waltenberger J, Becker PM, Vander Kooi CW, Biochemistry 2013 Oct 52 43 7551-8
Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1.
Parker MW, Xu P, Li X, Vander Kooi CW, The Journal of biological chemistry 2012 Mar 287 14 11082-9
Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition.
Parker MW, Xu P, Guo HF, Vander Kooi CW, PloS one 2012 7 11 e49177
Furin processing of semaphorin 3F determines its anti-angiogenic activity by regulating direct binding and competition for neuropilin.
Parker MW, Hellman LM, Xu P, Fried MG, Vander Kooi CW, Biochemistry 2010 May 49 19 4068-75

Honors & Awards

  • Cancer Prevention & Research Institute of Texas (CPRIT) Scholar
    (2020)
  • Cecil H. and Ida Green Endowed Scholar in Biomedical Computational Science
    (2020)
  • NIH NRSA F32 Postdoctoral Fellow
    (2015-2018)
  • University of Kentucky Robert L. Lester Award
    (2014-2014)
  • University of Kentucky College of Medicine Research Incentive Award
    (2010-2013)
  • Western Colorado University Alumni Award for Excellence
    (2010-2010)
  • Western Colorado University Noddin-McKenny Award
    (2009-2009)
  • Western Colorado University Thornton Research Scholar
    (2008-2010)