Chengheng Liao, Ph.D.

 Featured Publications

Von Hippel-Lindau protein signalling in clear cell renal cell carcinoma.

Liao C, Hu L, Zhang Q, Nat Rev Urol 2024 May

Tumor hypoxia: From basic knowledge to therapeutic implications.

Liao C, Liu X, Zhang C, Zhang Q, Semin Cancer Biol 2023 Jan 88 172-186

Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers.

Liao C, Glodowski CR, Fan C, Liu J, Mott KR, Kaushik A, Vu H, Locasale JW, McBrayer SK, DeBerardinis RJ, Perou CM, Zhang Q, Cancer Res 2021 Dec

ZHX2 promotes HIF1a oncogenic signaling in triple-negative breast cancer.

Fang W, Liao C, Shi R, Simon JM, Ptacek TS, Zurlo G, Ye Y, Han L, Fan C, Bao L, Ortiz CL, Lin HR, Manocha U, Luo W, Kim WY, Yang LW, Zhang Q, Elife 2021 Nov 10

Understanding the Oxygen-Sensing Pathway and Its Therapeutic Implications in Diseases.

Liao C, Zhang Q, Am J Pathol 2020 Aug 190 8 1584-1595

Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer.

Liao C, Zhang Y, Fan C, Herring LE, Liu J, Locasale JW, Takada M, Zhou J, Zurlo G, Hu L, Simon JM, Ptacek TS, Andrianov VG, Loza E, Peng Y, Yang H, Perou CM, Zhang Q, Cancer Discov 2020 Jul

Nitrogen regulator GlnR controls uptake and utilization of non-phosphotransferase-system carbon sources in actinomycetes.

Liao CH, Yao L, Xu Y, Liu WB, Zhou Y, Ye BC Proc. Natl. Acad. Sci. U.S.A. 2015 Dec 112 51 15630-5

Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis.

Zhang C, Yu M, Hepperla AJ, Zhang Z, Raj R, Zhong H, Zhou J, Hu L, Fang J, Liu H, Liang Q, Jia L, Liao C, Xi S, Simon JM, Xu K, Liu Z, Nam Y, Kapur P, Zhang Q, J Clin Invest 2024 Apr 134 8

Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma.

Hu L, Zhang Y, Guo L, Zhong H, Xie L, Zhou J, Liao C, Yao H, Fang J, Liu H, Zhang C, Zhang H, Zhu X, Luo M, von Kriegsheim A, Li B, Luo W, Zhang X, Chen X, Mendell JT, Xu L, Kapur P, Baldwin AS, Brugarolas J, Zhang Q, Mol Cell 2024 Jan

FOXP1 and KLF2 reciprocally regulate checkpoints of stem-like to effector transition in CAR T cells.

Zhu Z, Lou G, Teng XL, Wang H, Luo Y, Shi W, Yihunie K, Hao S, DeGolier K, Liao C, Huang H, Zhang Q, Fry T, Wang T, Yao C, Wu T, Nat Immunol 2023 Nov

• American Urological Association (AUA) Urology Care Foundation Research Scholar Award (2024)
  
• National Scholarship for Graduated Student, Ministry of Education of China (2014)
  

• American Association for Cancer Research (2020)
• American Urological Association (2024)