Cheng Zhang, Ph.D. Instructor School Medical School Department Pathology Research Interest kidney cancer, hypoxia signaling, VHL, post-translational modification Publications Featured Publications Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis. Zhang C, Yu M, Hepperla AJ, Zhang Z, Raj R, Zhong H, Zhou J, Hu L, Fang J, Liu H, Liang Q, Jia L, Liao C, Xi S, Simon JM, Xu K, Liu Z, Nam Y, Kapur P, Zhang Q, J Clin Invest 2024 Apr 134 8 Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma. Hu L, Zhang Y, Guo L, Zhong H, Xie L, Zhou J, Liao C, Yao H, Fang J, Liu H, Zhang C, Zhang H, Zhu X, Luo M, von Kriegsheim A, Li B, Luo W, Zhang X, Chen X, Mendell JT, Xu L, Kapur P, Baldwin AS, Brugarolas J, Zhang Q, Mol Cell 2024 Feb 84 4 776-790.e5 Endothelial Mitochondria-Associated Membranes (MAMs) Isolation by Percoll Step Gradients. Baldini M, Zhang C, Yu J, Methods Mol Biol 2024 2782 113-122 Pulsatilla Saponins Inhibit Experimental Lung Metastasis of Melanoma via Targeting STAT6-Mediated M2 Macrophages Polarization. Yang X, Wu M, Yan X, Zhang C, Luo Y, Yu J, Molecules 2023 Apr 28 9 Tumor hypoxia: From basic knowledge to therapeutic implications. Liao C, Liu X, Zhang C, Zhang Q, Semin Cancer Biol 2023 Jan 88 172-186 Histone H3 proline 16 hydroxylation regulates mammalian gene expression. Liu X, Wang J, Boyer JA, Gong W, Zhao S, Xie L, Wu Q, Zhang C, Jain K, Guo Y, Rodriguez J, Li M, Uryu H, Liao C, Hu L, Zhou J, Shi X, Tsai YH, Yan Q, Luo W, Chen X, Strahl BD, von Kriegsheim A, Zhang Q, Wang GG, Baldwin AS, Zhang Q, Nat Genet 2022 Nov 54 11 1721-1735 An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma. Zhou J, Simon JM, Liao C, Zhang C, Hu L, Zurlo G, Liu X, Fan C, Hepperla A, Jia L, Tcheuyap VT, Zhong H, Elias R, Ye J, Henne WM, Kapur P, Nijhawan D, Brugarolas J, Zhang Q, Mol Cell 2022 Aug 82 16 3030-3044.e8 Enterobacter aerogenes ZDY01 inhibits choline-induced atherosclerosis through CDCA-FXR-FGF15 axis. Tang J, Qin M, Tang L, Shan D, Zhang C, Zhang Y, Wei H, Qiu L, Yu J, Food Funct 2021 Oct 12 20 9932-9946 MAP Kinase Phosphatase-5 Deficiency Protects Against Pressure Overload-Induced Cardiac Fibrosis. Zhong C, Min K, Zhao Z, Zhang C, Gao E, Huang Y, Zhang X, Baldini M, Roy R, Yang X, Koch WJ, Bennett AM, Yu J, Front Immunol 2021 12 790511 Tiliroside Ameliorates Ulcerative Colitis by Restoring the M1/M2 Macrophage Balance via the HIF-1α/glycolysis Pathway. Zhuang H, Lv Q, Zhong C, Cui Y, He L, Zhang C, Yu J, Front Immunol 2021 12 649463 Results 1-10 of 15 1 2 Next Last Honors & Awards American Heart Association (AHA) Postdoctoral Fellowship (2017-2019) Young Investigator Award (2018)CAAC-ATVB Metabolic Vascular Disease Symposium
