Spencer L. Bowen, Ph.D., is an Assistant Professor of Radiology at UT Southwestern Medical Center, and a member of its Radiology Research section who serves as a Positron Emission Tomography (PET) research scientist.

Dr. Bowen holds a bachelor's degree in biomedical engineering from the University of Washington in Seattle. He earned his doctoral degree in biomedical engineering from the University of California at Davis, and then worked as a research fellow at Massachusetts General Hospital in Charlestown, Massachusetts.

Prior to joining the UT Southwestern faculty in 2020, he served as a research assistant professor at the Fralin Biomedical Research Institute at VTC and the Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences in Roanoke, Virginia.

Dr. Bowen's research focuses on the development of nuclear tomographic scanner tools to enable precision imaging for the care and study of oncology, neurology, and cardiology patients. He investigates advanced acquisition techniques, reconstruction algorithms, and post-processing methods for quantitative hybrid (PET-CT and PET-MR) and standalone PET cameras.

His research activities have resulted in more than a dozen original scientific publications, have been featured on the cover of the Journal of Nuclear Medicine, and covered by the press.

Dr. Bowen serves as a reviewer for several publications, including the Journal of Nuclear Medicine Technology, Journal of Nuclear Medicine, Medical Physics, European Journal of Nuclear Medicine and Molecular Imaging - Physics, Physics in Medicine and Biology, and IEEE's Transactions on Nuclear Science and Transactions on Medical Imaging.

Research Interest

  • Advanced acquisition techniques, reconstruction algorithms, and post-processing methods for quantitative PET imaging


Featured Publications LegendFeatured Publications

Different partial volume correction methods lead to different conclusions: An (18)F-FDG-PET study of aging.
Greve DN, Salat DH, Bowen SL, Izquierdo-Garcia D, Schultz AP, Catana C, Becker JA, Svarer C, Knudsen GM, Sperling RA, Johnson KA, Neuroimage 2016 05 132 334-343
Effects of ferumoxytol on quantitative PET measurements in simultaneous PET/MR whole-body imaging: a pilot study in a baboon model.
Borra RJ, Cho HS, Bowen SL, Attenberger U, Arabasz G, Catana C, Josephson L, Rosen BR, Guimaraes AR, Hooker JM, EJNMMI Phys 2015 Dec 2 1 6
Masamune: a tool for automatic dynamic PET data processing, image reconstruction and integrated PET/MRI data analysis.
Chonde DB, Izquierdo-Garcia D, Chen K, Bowen SL, Catana C, EJNMMI Phys 2014 Jul 1 Suppl 1 A57
Quantification with a dedicated breast PET/CT scanner.
Bowen SL, Ferrero A, Badawi RD, Med Phys 2012 May 39 5 2694-707
High-resolution (18)F-FDG PET with MRI for monitoring response to treatment in rheumatoid arthritis.
Chaudhari AJ, Bowen SL, Burkett GW, Packard NJ, Godinez F, Joshi AA, Naguwa SM, Shelton DK, Hunter JC, Boone JM, Buonocore MH, Badawi RD, Eur. J. Nucl. Med. Mol. Imaging 2010 May 37 5 1047
An X-Ray computed tomography/positron emission tomography system designed specifically for breast imaging.
Boone JM, Yang K, Burkett GW, Packard NJ, Huang SY, Bowen S, Badawi RD, Lindfors KK, Technol Cancer Res Treat 2010 Feb 9 1 29-44
Simulation study of spatial resolution and sensitivity for the tapered depth of interaction PET detectors for small animal imaging.
St James S, Yang Y, Bowen SL, Qi J, Cherry SR, Phys Med Biol 2010 Jan 55 2 N63-74

Honors & Awards

  • Trainee Award
    IEEE Medical Imaging Conference (2011)
  • Trainee Award
    IEEE Medical Imaging Conference (2009)
  • Young Investigator Award, 2nd runner up
    Computer and Instrumentation Council, Society of Nuclear Medicine, Annual Meeting (2008)
  • Trainee Award
    IEEE Medical Imaging Conference (2006)

Professional Associations/Affiliations

  • Institute of Electrical and Electronics Engineers
  • Society of Nuclear Medicine and Molecular Imaging