Kimberly Chan, Ph.D. Assistant Professor School Medical School Department Advanced Imaging Research Center | Biomedical Engineering | Radiology Graduate Programs Biomedical Engineering Biography Dr. Kimberly Chan is an Assistant Professor and NIH-FIRST scholar in the Advanced Imaging Research Center and Department of Biomedical Engineering at UT Southwestern Medical Center. Dr. Chan received a bachelor's degree in bioengineering with Honors from the University of California, Berkeley and a doctoral degree in biomedical engineering from the Johns Hopkins School of Medicine under the supervision of Dr. Richard Edden and Dr. Peter Barker. After completing her Ph.D. in 2019, she joined the University of Texas Southwestern (UTSW) as a Postdoctoral Researcher and later as an Instructor in the Advanced Imaging Research Center and Department of Psychiatry in Dr. Anke Henning's group. Dr. Chan's research focuses on the development and application of novel magnetic resonance spectroscopy techniques to answer key biological questions in clinical neuroscience and improve the diagnosis, disease monitoring, and treatment planning of neurological diseases and psychiatric disorders. Research Interest Development and clinical translation of next-generation 2HG magnetic resonance spectroscopy methods as diagnostic, prognostic, and treatment planning tools for precision oncology. Multimodal imaging to better understand the pathophysiology of mood disorders with an aim of forming a basis for improving diagnostics and treatment. Novel single-voxel and multi-voxel proton MRS methods to investigate brain metabolism and improve diagnostic medicine. Publications Featured Publications Magnetic Resonance Spectroscopy for Cervical Cancer: Review and Potential Prognostic Applications. Iqbal Z, Albuquerque K, Chan KL, Cancers (Basel) 2024 Jun 16 11 1H and 31P magnetic resonance spectroscopy reveals potential pathogenic and biomarker metabolite alterations in Lafora disease. Chan KL, Panatpur A, Messahel S, Dahshi H, Johnson T, Henning A, Ren J, Minassian BA, Brain Commun 2024 6 2 fcae104 Metabolic profile of complete spinal cord injury in pons and cerebellum: A 3T 1H MRS study. Richter JK, Vallesi V, Zölch N, Chan KL, Hunkeler N, Abramovic M, Hashagen C, Christiaanse E, Shetty G, Verma RK, Berger MF, Frotzler A, Eisenlohr H, Eriks Hoogland I, Scheel-Sailer A, Wyss PO, Sci Rep 2023 May 13 1 7245 Improved signal-to-noise performance of MultiNet GRAPPA 1 H FID MRSI reconstruction with semi-synthetic calibration data. Chan KL, Ziegs T, Henning A, Magn Reson Med 2022 10 88 4 1500-1515 Sensorimotor Cortex GABA Moderates the Relationship between Physical Exertion and Assessments of Effort. Hu EJ, Casamento-Moran A, Galaro JK, Chan KL, Edden RAE, Puts NAJ, Chib VS, J Neurosci 2022 Aug 42 31 6121-6130 Hippocampal and striatal responses during motor learning are modulated by prefrontal cortex stimulation. Gann MA, King BR, Dolfen N, Veldman MP, Chan KL, Puts NAJ, Edden RAE, Davare M, Swinnen SP, Mantini D, Robertson EM, Albouy G, Neuroimage 2021 Aug 237 118158 Improved prospective frequency correction for macromolecule-suppressed GABA editing with metabolite cycling at 3T. Chan KL, Hock A, Edden RAE, MacMillan EL, Henning A, Magn Reson Med 2021 Aug Multimodal Imaging and Visual Evoked Potentials Reveal Key Structural and Functional Features That Distinguish Symptomatic From Presymptomatic Huntington's Disease Brain. Thota SM, Chan KL, Pradhan SS, Nagabushana B, Priyanka GB, Sunil HV, Kanneganti V, Vasoya P, Vinnakote KM, Viswamitra S, Thambisetty M, Kumar D, Tiwari V, Joshy EV, Sivaramakrishnan V, Neurol India 2021 69 5 1247-1258 Comparison of Multivendor Single-Voxel MR Spectroscopy Data Acquired in Healthy Brain at 26 Sites. Považan M, Mikkelsen M, Berrington A, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DYT, Craven AR, Cuypers K, Dacko M, Duncan NW, Dydak U, Edmondson DA, Ende G, Ersland L, Forbes MA, Gao F, Greenhouse I, Harris AD, He N, Heba S, Hoggard N, Hsu TW, Jansen JFA, Kangarlu A, Lange T, Lebel RM, Li Y, Lin CE, Liou JK, Lirng JF, Liu F, Long JR, Ma R, Maes C, Moreno-Ortega M, Murray SO, Noah S, Noeske R, Noseworthy MD, Oeltzschner G, Porges EC, Prisciandaro JJ, Puts NAJ, Roberts TPL, Sack M, Sailasuta N, Saleh MG, Schallmo MP, Simard N, Stoffers D, Swinnen SP, Tegenthoff M, Truong P, Wang G, Wilkinson ID, Wittsack HJ, Woods AJ, Xu H, Yan F, Zhang C, Zipunnikov V, Zöllner HJ, Edden RAE, Barker PB, Radiology 2020 Feb 191037 Retrospective motion compensation for edited MR spectroscopic imaging. Chan KL, Barker PB, Neuroimage 2019 Nov 202 116141 Results 1-10 of 27 1 2 3 Next Last Honors & Awards 1st Place Poster and Presentation Award, ISMRM MR Spectroscopy Study Group (2017) Magnetic Resonance in Medicine Editor's Pick for the month of February (2017) 2nd Place, Best Presentation Award, 19th MR Division Retreat - Johns Hopkins University (2016) Educational stipend, International Society for Magnetic Resonance in Medicine (2016-2018) Poster Award, World Molecular Imaging Congress Annual Meeting (2015) National Science Foundation Graduate Research Fellowship Program Honorable Mention (2014) Dean's Honors List, University of California, Berkeley (2013) Honors in Bioengineering, University of California, Berkeley (2013) Summer Undergraduate Research Fellowship, Mayo Clinic Graduate School (2012) American Association for the Advancement of Science (AAAS) EntryPoint! Fellowship (2011) Berkeley Undergraduate Scholarship (2009-2013) Margaret Webb Memorial Scholarship (2009)
