Pancheng Xie, Ph.D.

 Featured Publications

Mammalian circadian clock proteins form dynamic interacting microbodies distinct from phase separation.

Xie P, Xie X, Ye C, Dean KM, Laothamatas I, Taufique SKT, Takahashi J, Yamazaki S, Xu Y, Liu Y, Proc Natl Acad Sci U S A 2023 Dec 120 52 e2318274120

Decoupling PER phosphorylation, stability and rhythmic expression from circadian clock function by abolishing PER-CK1 interaction.

An Y, Yuan B, Xie P, Gu Y, Liu Z, Wang T, Li Z, Xu Y, Liu Y, Nat Commun 2022 Jul 13 1 3991

High-throughput discovery of genetic determinants of circadian misalignment.

Zhang T, Xie P, Dong Y, Liu Z, Zhou F, Pan D, Huang Z, Zhai Q, Gu Y, Wu Q, Tanaka N, Obata Y, Bradley A, Lelliott CJ, Nutter LMJ, McKerlie C, Flenniken AM, Champy MF, Sorg T, Herault Y, Angelis MH, Durner VG, Mallon AM, Brown SDM, Meehan T, Parkinson HE, Smedley D, Lloyd KCK, Yan J, Gao X, Seong JK, Wang CL, Sedlacek R, Liu Y, Rozman J, Yang L, Xu Y, PLoS Genet. 2020 Jan 16 1 e1008577

Distinct Roles of HDAC3 in the Core Circadian Negative Feedback Loop Are Critical for Clock Function.

Shi G, Xie P, Qu Z, Zhang Z, Dong Z, An Y, Xing L, Liu Z, Dong Y, Xu G, Yang L, Liu Y, Xu Y Cell Rep 2016 Jan

eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons.

Yang Q, Yu CH, Zhao F, Dang Y, Wu C, Xie P, Sachs MS, Liu Y, Nucleic Acids Res. 2019 Aug

CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.

Lin R, Mo Y, Zha H, Qu Z, Xie P, Zhu ZJ, Xu Y, Xiong Y, Guan KL Mol. Cell 2017 Oct 68 1 198-209.e6

Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII.

Chu M, Li T, Shen B, Cao X, Zhong H, Zhang L, Zhou F, Ma W, Jiang H, Xie P, Liu Z, Dong N, Xu Y, Zhao Y, Xu G, Lu P, Luo J, Wu Q, Alitalo K, Koh GY, Adams RH, He Y Elife 2016 Dec 5

Correlated Evolution Between CK1d and the Serine Rich Motif Contributes to Regulating the Mammalian Circadian Clock.

Xing L, An Y, Shi G, Yan J, Xie P, Qu Z, Zhang Z, Liu Z, Pan D, Xu Y J. Biol. Chem. 2016 Nov

Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve.

Dong Z, Huang M, Liu Z, Xie P, Dong Y, Wu X, Qu Z, Shen B, Huang X, Zhang T, Li J, Liu J, Yanase T, Zhou C, Xu Y Cell Death Differ. 2016 May

Loss of ZBTB20 impairs circadian output and leads to unimodal behavioral rhythms.

Qu Z, Zhang H, Huang M, Shi G, Liu Z, Xie P, Li H, Wang W, Xu G, Zhang Y, Yang L, Huang G, Takahashi JS, Zhang WJ, Xu Y Elife 2016 5

• National Scholarship for Graduated Student
  Ministry of Education of China (2017-2017)
• National Scholarship for Undergraduate Students
  Ministry of Education of China (2012-2012)