Jinhai Yu, Ph.D. Assistant Professor School Medical School Department Center for Human Nutrition | Internal Medicine Biography Download Curriculum Vitae Jinhai Yu obtained his PhD in Cell Biology in 2014 from Institute of Biophysics, Chinese Academy of Sciences for research on lipid droplet biology in brown adipose tissue and adrenal gland. From 2014-2018 he was a postdoctoral research scientist in Tsinghua Univeristy where he studied fatty acids and mTOR signaling. From 2018-2021 he was a postdoctoral research scientist in the Center for Human Nutrition at UT Southwestern where he studied non-small cell lung cancer (NSCLC) associated Cachexia. Now he focuses on studying how STK11/LKB1 mutants in NSCLC cause cachexia through GDF15. Research Interest Cancer Cachexia, Lipid Metabolism, Lipid Droplet Publications Tumor loss-of-function mutations in STK11/LKB1 induce cachexia Iyengar P, Gandhi AY, Granados J, Guo T, Gupta A, Yu J, Llano EM, Zhang F, Gao A, Kandathil A, Williams D, Gao B, Girard L, Malladi V, Shelton JM, Evers BM, Hannan R, Ahn C, Minna JD, Infante RE JCI Insight 2023 8 Cytokine-Mediated STAT3 Transcription Supports ATGL/CGI-58-Dependent Adipocyte Lipolysis in Cancer Cachexia Gandhi AY, Yu J, Gupta A, Guo T, Iyengar P, Infante RE Frontiers in Oncology 2022 Jun 12 LIFR-α-dependent adipocyte signaling in obesity limits adipose expansion contributing to fatty liver disease Guo T, Gupta A, Yu J, Granados JZ, Gandhi AY, Evers BM, Iyengar P, Infante RE iScience 2021 Mar 24 The Adrenal Lipid Droplet is a New Site for Steroid Hormone Metabolism Yu J, Zhang L, Li Y, Zhu X, Xu S, Zhou XM, Wang H, Zhang H, Liang B, Liu P Proteomics 2018 Dec 18 Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions Xu D, Li Y, Wu L, Li Y, Zhao D, Yu J, Huang T, Ferguson C, Parton RG, Yang H, Li P Journal of Cell Biology 2018 Mar 217 975-995 HDAC6-mediated acetylation of lipid droplet-binding protein CIDEC regulates fat-induced lipid storage Li P, Qian H, Chen Y, Nian Z, Su L, Yu H, Chen FJ, Zhang X, Xu W, Zhou L, Liu J, Yu J, Yu L, Gao Y, Zhang H, Zhang H, Zhao S, Yu L, Xiao RP, Bao Y, Hou S, Li P, Li J, Deng H, Jia W Journal of Clinical Investigation 2017 Apr 127 1353-1369 The size matters: regulation of lipid storage by lipid droplet dynamics Yu J, Li P Science China Life Sciences 2017 Jan 60 46-56 Morphologically and Functionally Distinct Lipid Droplet Subpopulations Zhang S, Wang Y, Cui L, Deng Y, Xu S, Yu J, Cichello S, Serrero G, Ying Y, Liu P Scientific reports 2016 Jul 6 Differential roles of cell death-inducing DNA fragmentation factor-α-like effector (CIDE) proteins in promoting lipid droplet fusion and growth in subpopulations of hepatocytes Xu W, Wu L, Yu M, Chen FJ, Arshad M, Xia X, Ren H, Yu J, Xu L, Xu D, Li JZ, Li P, Zhou L Journal of Biological Chemistry 2016 Feb 291 4282-4293 Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment Yu J, Zhang S, Cui L, Wang W, Na H, Zhu X, Li L, Xu G, Yang F, Christian M, Liu P Biochimica et Biophysica Acta - Molecular Cell Research 2015 May 1853 918-928 Results 1-10 of 17 1 2 Next Last Honors & Awards China Postdoctoral International Academic Exchange Program Award (2016-2016) FASEB Science Research Conference Travel AwardFor FASEB Lipid Droplet Conference (2016-2016) National Natural Science Foundation of China Grant (2016-2017) China Postdoctoral Science Foundation Grant Award (2015-2016)
