Ye Tao, Ph.D. - Faculty Profile

Biography

Ye Tao, Ph.D., Instructor of Radiation Oncology at UT Southwestern Medical Center, received his bachelor's degree from the Department of Chemical Engineering at Chongqing University in Chongqing, China. He then completed his Ph.D. in organic chemistry at the University of Houston, Texas. Dr. Tao conducted his postdoctoral research in the Department of Biochemistry at UT Southwestern Medical Center under the mentorship of Dr. Jef De Brabander.

Research Interest

Chemical biology related to novel cancer target identification
Structure-based anti-cancer drug design

Publications

Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3: Tao Y, Budhipramono A, Huang J, Fang M, Xie S, Kim J, Khivansara V, Dominski Z, Tong L, De Brabander JK, Nijhawan D Cell Chemical Biology 2024 Jan 31 139-149.e14
Homoallyl alcohol as an allylation reagent for termination of the Catellani-Lautens reaction via retro-allylation: Du X, Yang X, Wang H, Li X, Wang M, Li X, Tao Y, Yang Y, Tan X, Ren F, Zhou PX, Liang YM Organic Chemistry Frontiers 2022 Dec 10 898-904
Correction: Diastereoselective synthesis of 1,3-disubstituted isoindolines and sultams: Via bronsted acid catalysis (Chemical Communications (2018) 54 (11292-11295) DOI: 10.1039/c8cc04946g): Tao Y, Gilbertson SR Chemical Communications 2020 Feb 56 2211-2213
Diastereoselective synthesis of 1,3-disubstituted isoindolines and sultams via bronsted acid catalysis: Tao Y, Gilbertson SR Chemical Communications 2018 54 11292-11295
Two aromatic rings coupled a sulfur-containing group to favor protein electron transfer by instantaneous formations of Π∴S:Π虠Π:S∴Π or Π∴Π:S虠Π:Π∴S five-electron bindings: Sun W, Ren H, Tao Y, Xiao D, Qin X, Deng L, Shao M, Gao J, Chen X Journal of Physical Chemistry C 2015 Apr 119 9149-9158
Potent relay stations for electron transfer in proteins: π∴π Three-electron bonds: Sun W, Dai H, Tao Y, Xiao D, Zhang Y, Wei Z, Chen X Journal of Physical Chemistry C 2013 Sep 117 18325-18333
Aromatic residues regulating electron relay ability of S-containing amino acids by formations of Sπ multicenter three-electron bonds in proteins: Chen X, Tao Y, Li J, Dai H, Sun W, Huang X, Wei Z Journal of Physical Chemistry C 2012 Sep 116 19682-19688