Baowei Fei, Ph.D.

Dr. Fei is Director of the Center for Imaging and Surgical Innovation (CISI), a Professor of Radiology at UT Southwestern Medical Center, a Professor of Bioengineering and Cecil H. and Ida Green Chair in Systems Biology Science at the University of Texas at Dallas. He is Director of Quantitative Bioimaging Laboratory (https://www.fei-lab.org). Before he was recruited to Dallas, Dr. Fei was Associate Professor with tenure in the Department of Radiology and Imaging Sciences and Department of Mathematics & Computer Science at Emory University where he was Director of the Precision Imaging – Quantitative, Molecular & Image-Guided Technologies Program. Dr. Fei was a Georgia Cancer Coalition Distinguished Scholar, served as a faculty member, and mentored Ph.D. students in the Joint Department of Biomedical Engineering at Emory University and Georgia Institute of Technology.

Dr. Fei received his Ph.D. and M.Sc. degrees from Case Western Reserve University in Ohio. With a prestigious scholarship from the U.S. Department of Defense Congressionally Directed Medical Research Program, Dr. Fei completed his post-doctoral training at the same institution. He then became an Assistant Professor in the Departments of Radiology and Biomedical Engineering at Case Western Reserve University.

Dr. Fei received numerous awards at the national and local levels. In 2013, Dr. Fei was selected as a Distinguished Investigator by the Academy for Radiology & Biomedical Imaging Research. In the same year, he as a faculty member received the Emory 1% Award. In 2010, he received the Young Investigator Award from the Society of Nuclear Medicine and Molecular Imaging. He was a recipient of the U.S. Department of Defense Post-Doctoral Traineeship Award. He was recognized as a Distinguished Scholar by the Georgia Cancer Coalition and the Governor of Georgia in 2009.

Dr. Fei is a national leader in quantitative imaging and image-guided interventions. He serves as Conference Chair for the International Conference of SPIE Medical Imaging – Image-Guided Procedures, Robotics Interventions, and Modeling from 2017-2020. The SPIE Medical Imaging Conference is the internationally recognized premier forum for reporting state-of-the-art research and development in medical imaging. Dr. Fei served as the Chair for the National Institute of Health (NIH) Study Section ZRG1 SBIB-J (56) on Imaging and Image-guided Interventions and as co-Chair for multiple NIH and Department of Defense (DOD) Study Section Panels. He served as an Associate Editor for Medical Physics, an Editorial Board Member for the Journal of Biomedical Optics and other five journals in the field of biomedical imaging, and a reviewer for more than 20 international journals in medical imaging. Dr. Fei is a Senior Member of the International Society for Optics and Photonics (SPIE) and the Institute of Electrical and Electronic Engineers (IEEE). He is also a member of American Association of Physicists in Medicine (AAPM), World Molecular Imaging Society (WMIS), and Society of Nuclear Medicine and Molecular Imaging (SNMMI). Dr. Fei has published more than 200 referred papers in biomedical imaging, image-guided interventions, and artificial intelligence.

Dr. Fei served as Principal Investigator (PI) of 20 research grants from the National Institute of Health (NIH), Department of Defense (DOD), foundations, industry, state and local programs, and other agencies. He also served as co-investigator for more than 20 other funded grants. Dr. Fei led and completed a first-in-human clinical trial on PET/ultrasound fusion targeted biopsy of the prostate and contributed to the improvement of prostate cancer detection and patient care. Dr. Fei currently serves as PI for multiple NIH and other grants. 

Dr. Fei enjoys mentoring undergraduate and graduate students, post-doctoral fellows, and visiting scholars when they undertake research projects. His graduate students received multiple national awards at the International Conference of SPIE Medical Imaging and other organization.  His trainees have become faculty members in academic institutions in the USA and other countries. Dr. Fei envisions that biomedical imaging will be a leading force in a new era of precision medicine where quantitative methods of engineering and systems sciences have a pivotal role in disease detection, diagnostics, and treatment. The mission of his research lab is to shape and advance the science and technology of biomedical imaging through innovative research and inspiring education, with the goal of becoming a destination laboratory internationally recognized as a first choice of both researchers and students.

Dr. Fei is a Fellow of the International Society for Optics and Photonics (SPIE) and a Fellow of the American Institute for Medical and Biological Engineering (AIMBE). 

For more information, please visit his lab website at https://www.fei-lab.org.

E-mail: Baowei.Fei@UTSouthwestern.edu 

• Cancer research: prostate, head and neck, breast, pancreas, and brain
• Cardiovascular diseases: heart failure
• Image-guided interventions: image-guided surgery, therapy, biopsy, and drug delivery
• Imaging: biomedical imaging, digital imaging
• Machine learning and artificial intelligence (AI) for biomedical imaging applications
• Multimodality imaging: hyperspectral imaging, magnetic resonance imaging (MRI), positron emission tomography (PET), computed tomography (CT), and ultrasound imaging
• Neurodegenerative disorders
• Quantitative imaging: image processing & analysis, segmentation, classification, and registration
• Translational imaging: cellular & molecular imaging, small animal imaging, and clinical imaging
• Virtual reality, augmented reality, mixed reality for biomedical and clinical applications

Featured Publications

Unsupervised super-resolution reconstruction of hyperspectral histology images for whole-slide imaging.

Ma L, Rathgeb A, Mubarak H, Tran M, Fei B, J Biomed Opt 2022 May 27 5

Automatic detection of head and neck squamous cell carcinoma on histologic slides using hyperspectral microscopic imaging.

Ma L, Little JV, Chen AY, Myers L, Sumer BD, Fei B, J Biomed Opt 2022 Apr 27 4

Brain tumor IDH, 1p/19q, and MGMT molecular classification using MRI-based deep learning: an initial study on the effect of motion and motion correction.

Nalawade SS, Yu FF, Bangalore Yogananda CG, Murugesan GK, Shah BR, Pinho MC, Wagner BC, Xi Y, Mickey B, Patel TR, Fei B, Madhuranthakam AJ, Maldjian JA, J Med Imaging (Bellingham) 2022 Jan 9 1 016001

The effect of image annotation with minimal manual interaction for semiautomatic prostate segmentation in CT images using fully convolutional neural networks.

Shahedi M, Dormer JD, Halicek M, Fei B, Med Phys 2021 Dec

Deep learning-based segmentation of the placenta and uterus on MR images.

Shahedi M, Spong CY, Dormer JD, Do QN, Xi Y, Lewis MA, Herrera C, Madhuranthakam AJ, Twickler DM, Fei B, J Med Imaging (Bellingham) 2021 Sep 8 5 054001

The Contribution of Thoracic Radiation Dose Volumes to Subsequent Development of Cardiovascular Disease in Cancer Survivors.

Reilly CM, Higgins M, Butler J, Esiashvili N, Fei B, Flynn T, Dormer JD, Schreibmann E, J Cardiovasc Nurs 2021 Jul

Special Series Guest Editorial: Artificial Intelligence and Machine Learning in Biomedical Optics.

Shabestri B, Anastasio MA, Fei B, Leblond F, J Biomed Opt 2021 May 26 5

MRI-Based Deep-Learning Method for Determining Glioma MGMT Promoter Methylation Status.

Yogananda CGB, Shah BR, Nalawade SS, Murugesan GK, Yu FF, Pinho MC, Wagner BC, Mickey B, Patel TR, Fei B, Madhuranthakam AJ, Maldjian JA, AJNR Am J Neuroradiol 2021 05 42 5 845-852

Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo.

MacDonald TJ, Liu J, Yu B, Malhotra A, Munson J, Park JC, Wang K, Fei B, Bellamkonda R, Arbiser J, Cancers (Basel) 2021 Mar 13 6

Development of a real-time spectral imaging system using in-site micro-LED-based illumination and high-speed micro-camera for endoscopic applications.

Modir N, Shahedi M, Dormer J, Fei B, Proc SPIE Int Soc Opt Eng 2021 Mar 11654

• Chair, NIH Study Section
  National Institute of Biomedical Imaging and Bioengineering (NIBIB) Special Emphasis Panel (ZEB1 OSR-F M2) P41 Center Grant Panel (2022)
• Chair, NIH Study Section
  National Institutes of Health (NIH) Section Special Emphasis Panel ZRG1 SBIB-C (2022)
• Chair, NIH Study Section
  National Institutes of Health (NIH) Special Emphasis Panel ZRG1 MOSS-V (2022)
• Faculty Research Award – Full Professor Category
  Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas (2022)
• Best Paper Award
  Intuitive Surgical and SPIE Medical Imaging: Image-guided procedures, robotic interventions, and modeling (2020)
• Editor’s Choice Article
  Sensors, Basel, Switzerland (2020)
• Federal Research Innovation and Expenditures Dynamo (FRIEND) Award
  Office of Research and Innovation, The University of Texas at Dallas (2020)
• Fellow
  The International Society for Optics and Photonics (SPIE) (2019)
• Fellow
  American Institute for Medical and Biological Engineering (AIMBE) (2019)
• Cecil H. and Ida Green Chair in Systems Biology Science
  The University of Texas at Dallas (2018)
• Chair, NIH Study Section
  on Integrating Biospecimens into Clinical Assay Development, National Institutes of Health (NIH) (2018)
• Conference Chair
  The SPIE Medical Imaging: Image-guided Procedures, Robotic Interventions, and Modeling (2017-2020)
• Chair of NIH Study Section
  on Early Phase Clinical Trials in Imaging and Image-guided Interventions, National Institutes of Health (NIH) (2016-2017)
• Distinguished Investigator Award
  The Academy for Radiology & Biomedical Imaging Research, Washington, DC (2013)
• The Emory 1% Faculty Award
  Emory University School of Medicine, Atlanta, GA (2013)
• The Outstanding Young Investigator Award
  Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA (2013)
• Distinguished Cancer Scholar
  Georgia Cancer Coalition and the Governor of Georgia (2009)
• Young Investigator Award - First Place
  Computer and Instrumentation Council, The Society of Nuclear Medicine and Molecular Imaging (2009)
• Postdoctoral Traineeship Award
  U.S. Department of Defense (DOD) Congressionally Directed Medical Research Programs

• American Association of Physicists in Medicine (AAPM) (2009)
• American Institute for Medical and Biological Engineering (AIMBE) (2019)
• Institute of Electrical and Electronic Engineers, Inc. (IEEE) (2002)
• International Society for Optics and Photonics (SPIE) (2002)
• Radiological Society of Northern America (RSNA) (2011)
• Society of Nuclear Medicine and Molecular Imaging (SNMMI) (2006)
• World Molecular Imaging Society (WMIS) (2009)