Subhransu Sahoo, Ph.D. Instructor School Medical School Department Pathology Graduate Programs Cancer Biology Research Interest Cancer Biology Cancer Genetics Gynecologic oncology Tumor Microenvironment Publications Featured Publications Endometrial polyps are non-neoplastic but harbor epithelial mutations in endometrial cancer drivers at low allelic frequencies. Sahoo SS, Aguilar M, Xu Y, Lucas E, Miller V, Chen H, Zheng W, Cuevas IC, Li HD, Hitrys D, Wachsmann MB, Bishop JA, Cantarell B, Gagan J, Koduru P, SoRelle JA, Castrillon DH, Mod Pathol 2022 Jul FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity. Sahoo SS, Ramanand SG, Gao Y, Abbas A, Kumar A, Cuevas IC, Li HD, Aguilar M, Xing C, Mani RS, Castrillon DH, J Clin Invest 2022 06 132 12 Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition. Cuevas IC, Sahoo SS, Kumar A, Zhang H, Westcott J, Aguilar M, Cortez JD, Sullivan SA, Xing C, Hayes DN, Brekken RA, Bae-Jump VL, Castrillon DH, Proc Natl Acad Sci U S A 2019 12 116 51 25880-25890 The Emerging Role of the Microenvironment in Endometrial Cancer. Sahoo SS, Zhang XD, Hondermarck H, Tanwar PS, Cancers (Basel) 2018 Oct 10 11 Adipose-Derived VEGF-mTOR Signaling Promotes Endometrial Hyperplasia and Cancer: Implications for Obese Women. Sahoo SS, Lombard JM, Ius Y, O'Sullivan R, Wood LG, Nahar P, Jaaback K, Tanwar PS, Mol Cancer Res 2018 02 16 2 309-321 Inhibition of extracellular matrix mediated TGF-? signalling suppresses endometrial cancer metastasis. Sahoo SS, Quah MY, Nielsen S, Atkins J, Au GG, Cairns MJ, Nahar P, Lombard JM, Tanwar PS, Oncotarget 2017 Sep 8 42 71400-71417 Reliable Identification of Endometrial Precancers Through Combined Pax2, ?-Catenin, and Pten Immunohistochemistry. Aguilar M, Chen H, Rivera-Colon G, Niu S, Carrick K, Gwin K, Cuevas IC, Sahoo SS, Li HD, Zhang S, Zheng W, Lucas E, Castrillon DH, Am J Surg Pathol 2022 03 46 3 404-414 A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response. Li HD, Lu C, Zhang H, Hu Q, Zhang J, Cuevas IC, Sahoo SS, Aguilar M, Maurais EG, Zhang S, Wang X, Akbay EA, Li GM, Li B, Koduru P, Ly P, Fu YX, Castrillon DH, JCI Insight 2020 07 5 14 Results 1-8 of 8 1 Professional Associations/Affiliations American Association for Cancer Research (2020) Society for Reproductive Biology (2018)
