Seher Yuksel, Ph.D.

 Featured Publications

Lipid Composition and Thermotropic Properties of Meibum of Animal Models and Humans with Meibomian Gland Dysfunction.

Butovich IA, Wojtowicz JC, Wilkerson A, Yuksel S, Int J Mol Sci 2025 Nov 26 23

Aging Affects Lipid Homeostasis in Lacrimal Glands by Upregulating Lipogenesis and Changing Its Specificity.

Yuksel S, Kumar P, Krenz SE, Scholand KK, Yu Z, Ivanova A, Makarenkova HP, Hamm-Alvarez SF, Butovich IA, de Paiva CS, Invest Ophthalmol Vis Sci 2025 Oct 66 13 1

Biosynthesis of fatty aldehydes and alcohols in the eye and their role in meibogenesis.

Yuksel S, Butovich IA, J Biol Chem 2025 Jun 110330

Dysregulation of Lipid Metabolism in Aging Meibomian Glands and Its Molecular Markers.

Butovich IA, Wilkerson A, Yuksel S, Int J Mol Sci 2023 Aug 24 17

Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis.

Butovich IA, Wilkerson A, Goggans KR, Belyaeva OV, Kedishvili NY, Yuksel S, J Biol Chem 2023 Jun 299 6 104725

Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis.

Yuksel S, Aredo B, Zegeye Y, Zhao CX, Tang M, Li X, Hulleman JD, Gautron L, Ludwig S, Moresco EMY, Butovich IA, Beutler BA, Ufret-Vincenty RL, Commun Biol 2023 May 6 1 533

Probing dietary triacylglycerol metabolism and meibogenesis in mice: A stable isotope-labeled tracer liquid chromatography-tandem mass spectrometry study.

Butovich IA, Yuksel S, Wilkerson A, J Biol Chem 2023 Apr 299 4 103046

Lipid composition determines thermotropic properties of meibum of animals and humans with Meibomian gland disorders.

Butovich IA, Wojtowicz JC, Wilkerson A, Yuksel S, bioRxiv 2025 Aug

Comparative Analysis of Age-Associated Changes in Meibum Composition, Distribution, and Function in Mice With Altered Hyaluronan Expression.

Verma S, Montoya PAG, Sun M, Puri S, Yuksel S, Wilkerson A, Gesteira TF, Butovich IA, Coulson-Thomas VJ, Invest Ophthalmol Vis Sci 2025 Jul 66 9 72

Exploring the activity of short-chain dehydrogenases/reductases SDR16C5 and SDR16C6 in fatty aldehyde biosynthetic pathway using liquid chromatography/mass spectrometry

Seher Yuksel, Olga Belyaeva, Natalia Kedishvili, Igor Butovich JBC 2025 301 5, Supplement 109397

• Journal Cover
  Investigative Ophthalmology & Visual Science (IOVS), October 2025 Vol.66, No.13 (2025)
• ARVO Retina Research Foundation/Joseph M. and Eula C. Lawrence Travel Award
  (2022)
• UT Southwestern Medical Center / The PDA Travel Award
  (2020)
• The Scientific and Technological Research Council of Türkiye TUBITAK-2219 International Postdoctoral Research Fellowship
  (2018-2019)
• Poster Award
  23rd National Biochemistry Congress, Türkiye (2011)

• American Association for The Advancement of Science (AAAS) (2022)
• American Society for Biochemistry and Molecular Biology (ASBMB) (2024)
• National Postdoctoral Association (NPA) (2021)
• The Association for Research in Vision and Ophthalmology (ARVO) (2018)
• Turkish Biochemical Society (The Constituent Society of the Federation of European Biochemical Societies (FEBS)) (2011)