Seher Yuksel, Ph.D.

 Featured Publications

Meibomian gland lipid alterations and ocular surface sequela in Awat2 knockout murine model of meibomian gland dysfunction and evaporative dry eye disease.

Hisey EA, Wong S, Park S, Gamarra KA, Adelman SA, Knickelbein KE, Quan M, Ferneding MH, McCorkell M, Daley N, Ureno V, Le S, Ardon M, Williams L, Puentes B, Bowman M, Motta MJ, Pham HQH, Wilkerson A, Yuksel S, Jester JV, Thomasy SM, Morgan JT, Butovich IA, Leonard BC, Ocul Surf 2024 Oct 34 489-503

Non-redundant role of leishmanolysin-like (Lmln) zinc-metallopeptidase in retinal homeostasis.

Ufret-Vincenty RL, Kirman DC, Ulker-Yilmazer G, Aredo B, Shrestha S, Turpin E, Yuksel S, Zegeye Y, Ludwig S, Moresco EMY, He YG, Beutler B, Am J Ophthalmol 2024 Aug

Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface.

Wilkerson A, Yuksel S, Acharya R, Butovich IA, Invest Ophthalmol Vis Sci 2024 Jul 65 8 2

E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration.

Zegeye Y, Aredo B, Yuksel S, Kirman DC, Kumar A, Chen B, Turpin E, Shresta S, He YG, Gautron L, Tang M, Li X, DiCesare SM, Hulleman JD, Xing C, Ludwig S, Moresco EMY, Beutler BA, Ufret-Vincenty RL, Sci Rep 2024 Feb 14 1 3010

Dysregulation of Lipid Metabolism in Aging Meibomian Glands and Its Molecular Markers.

Butovich IA, Wilkerson A, Yuksel S, Int J Mol Sci 2023 Aug 24 17

Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis.

Butovich IA, Wilkerson A, Goggans KR, Belyaeva OV, Kedishvili NY, Yuksel S, J Biol Chem 2023 Jun 299 6 104725

Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis.

Yuksel S, Aredo B, Zegeye Y, Zhao CX, Tang M, Li X, Hulleman JD, Gautron L, Ludwig S, Moresco EMY, Butovich IA, Beutler BA, Ufret-Vincenty RL, Commun Biol 2023 May 6 1 533

Probing dietary triacylglycerol metabolism and meibogenesis in mice: A stable isotope-labeled tracer liquid chromatography-tandem mass spectrometry study.

Butovich IA, Yuksel S, Wilkerson A, J Biol Chem 2023 Apr 299 4 103046

Novel Lipids of the Rabbit Harderian Gland Improve Tear Stability in an Animal Model of Dry Eye Disease.

Butovich IA, Yuksel S, Leonard B, Gadek T, Polans AS, Albert DM, J Ocul Pharmacol Ther 2021 Dec 37 10 545-555

Differential effects of dietary cholesterol and triglycerides on the lipid homeostasis in Meibomian glands.

Butovich IA, Wilkerson A, Yuksel S, J Steroid Biochem Mol Biol 2021 Jul 211 105894

• ARVO Retina Research Foundation/Joseph M. and Eula C. Lawrence Travel Award
  (2022)
• UT Southwestern Medical Center / The PDA Travel Award
  (2020)
• The Scientific and Technological Research Council of Türkiye TUBITAK-2219 International Postdoctoral Research Fellowship
  (2018-2019)

• American Association for The Advancement of Science (AAAS) (2022)
• American Society for Biochemistry and Molecular Biology (ASBMB) (2024)
• National Postdoctoral Association (NPA) (2021)
• The Association for Research in Vision and Ophthalmology (ARVO) (2018)
• Turkish Biochemical Society (The Constituent Society of the Federation of European Biochemical Societies (FEBS)) (2011)