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Shuang Liang, Ph.D.

Shuang Liang, Ph.D.

Assistant Professor

School
Medical School
Department
Immunology
  • Research Interest
    • Alcoholic & non-alcoholic steatohepatitis
    • Hepatocellular carcinoma
    • Liver fibrosis
    • Sterile inflammation
  • Publications

    Star Featured Publications

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    Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease.
    Fujiwara N, Kubota N, Crouchet E, Koneru B, Marquez CA, Jajoriya AK, Panda G, Qian T, Zhu S, Goossens N, Wang X, Liang S, Zhong Z, Lewis S, Taouli B, Schwartz ME, Fiel MI, Singal AG, Marrero JA, Fobar AJ, Parikh ND, Raman I, Li QZ, Taguri M, Ono A, Aikata H, Nakahara T, Nakagawa H, Matsushita Y, Tateishi R, Koike K, Kobayashi M, Higashi T, Nakagawa S, Yamashita YI, Beppu T, Baba H, Kumada H, Chayama K, Baumert TF, Hoshida Y, Sci Transl Med 2022 Jun 14 650 eabo4474
    Non-degradable collagen increases liver fibrosis but not hepatocellular carcinoma in mice.
    Baglieri J, Zhang C, Liang S, Liu X, Nishio T, Rosenthal SB, Dhar D, Su H, Cong M, Jia J, Hosseini M, Karin M, Kisseleva T, Brenner DA, Am J Pathol 2021 Jun
    IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.
    Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, Zhao P, Brodt P, Mckillop IH, Quehenberger O, Dennis E, Saltiel A, Tsukamoto H, Gao B, Karin M, Brenner DA, Kisseleva T, J. Hepatol. 2019 Dec
    Emerging Role of Mitochondrial DNA as a Major Driver of Inflammation and Disease Progression.
    Zhong F, Liang S, Zhong Z, Trends Immunol. 2019 Nov
    Activated Hepatic Stellate Cells and Portal Fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice.
    Nishio T, Hu R, Koyama Y, Liang S, Rosenthal SB, Yamamoto G, Karin D, Baglieri J, Ma HY, Xu J, Liu X, Dhar D, Iwaisako K, Taura K, Brenner DA, Kisseleva T, J. Hepatol. 2019 May
  • Honors & Awards
    • American Institute for Cancer Research Investigator-initiated Grant Award
      (2023)
    • CPRIT Individual Investigator Research Award
      (2020)
    • American Association for the Study of Liver Diseases (AASLD) Pinnacle Research Award
      (2019)
    • Keystone Symposia scholarship on Injury, Inflammation and Fibrosis
      (2017)
  • Professional Associations/Affiliations
    • American Association for the Study of Liver Diseases (2017)