Biography

Dr.Divakar received his MSc and PhD degree from University of Hyderabad, India. Dr. Divakar moved to USA as a postdoc researcher at Temple University (Philadelphia) and later at Icahn School of Medicine at Mount Sinai (New York). After postdoctoral training, he joined as an Instructor the Department of Oncological Sciences at Mount Sinai. He later joined Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver diseases at UT Southwestern as Assistant Professor.

He has been involved in development of anti-cancer agents such as small molecule inhibitors of RAS, CDK4/6, PI3K, ARK5, RAF, ARK5, Tubulin, CK2, PLK, Topoisomerases, Integrins and other various kinases, some of which are under evaluation in clinical trials. His current research focuses on identification of novel pathways and development of therapeutics for chronic liver diseases such as viral hepatitis, alcoholic and non-alcoholic fatty liver disease, cirrhosis, and liver cancer.

Research Interest

  • Animal models
  • Autophagy
  • Liver diseases
  • Signal transduction
  • Small molecule inhibitors
  • Tumor suppressors

Publications

Featured Publications LegendFeatured Publications

TACI Isoforms Regulate Ligand Binding and Receptor Function.
Garcia-Carmona Y, Ting AT, Radigan L, Athuluri Divakar SK, Chavez J, Meffre E, Cerutti A, Cunningham-Rundles C Front Immunol 2018 9 2125
An efficient targeted drug delivery through apotransferrin loaded nanoparticles.
Krishna AD, Mandraju RK, Kishore G, Kondapi AK PLoS ONE 2009 4 10 e7240
A study of the topoisomerase II activity in HIV-1 replication using the ferrocene derivatives as probes.
Kondapi AK, Satyanarayana N, Saikrishna AD Arch. Biochem. Biophys. 2006 Jun 450 2 123-32
Mechanism of action of ferrocene derivatives on the catalytic activity of topoisomerase IIalpha and beta--distinct mode of action of two derivatives.
Sai Krishna AD, Panda G, Kondapi AK Arch. Biochem. Biophys. 2005 Jun 438 2 206-16

Honors & Awards

  • Suzan Komen Postdoctoral Fellowship
    Icahn School of Medicine at Mount Sinai NY, USA (2012-2015)
  • Senior Research fellowship (SRF)
    Council for Scientific and Industrial Research (CSIR), India (2006-2008)
  • Junior Research fellowship (JRF)
    Council for Scientific and Industrial Research (CSIR), India (2004-2006)

Professional Associations/Affiliations

  • AASLD (2018)
  • AACR (2011)